{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T06:21:35Z","timestamp":1782800495995,"version":"3.54.5"},"reference-count":19,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T00:00:00Z","timestamp":1649894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Aortic stenosis is the most common primary valve lesion requiring surgery or, especially for older patients, transcatheter intervention (TAVI). We showcase a successful transfemoral TAVI procedure in a very high-risk patient and an extremely tortuous S-shaped descending aorta, characterized by heavy calcifications and multiple strong resistance points. We demonstrated that transfemoral TAVI using the \u201cbuddy stiff guidewire\u201d technique could be a feasible, simple, quick, and easy procedure able to straighten an extremely abdominal aorta tortuosity. With all techniques available and careful pre-procedural planning, and thanks to the flexibility of new generation TAVI delivery systems, it is possible to safely perform the procedure even in the most challenging patients.<\/jats:p>","DOI":"10.3390\/ijerph19084763","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T21:44:06Z","timestamp":1649972646000},"page":"4763","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Management of Transcatheter Aortic Valve Implantation and Complex Aorta Anatomy: The Importance of Pre-Procedural Planning"],"prefix":"10.3390","volume":"19","author":[{"given":"Alfredo","family":"Intorcia","sequence":"first","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Ambrosini","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Capasso","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Granata","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Magliulo","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giannignazio Luigi","family":"Carbone","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Capobianco","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Rotondi","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Lanni","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiore","family":"Manganelli","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio","family":"Di Lorenzo","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Surgery, \u201cSan Giuseppe Moscati\u201d Hospital, 83100 Avellino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/eurheartj\/ehab395","article-title":"2021 ESC\/EACTS Guidelines for the management of valvular heart disease: Developed by the Task Force for the management of valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"43","author":"Vahanian","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.ijcard.2014.08.053","article-title":"The prevalence of aortic stenosis in the elderly in Iceland and predictions for the coming decades: The AGES-Reykjav\u00edk study","volume":"176","author":"Danielsen","year":"2014","journal-title":"Int. J. Cardiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.athoracsur.2019.01.031","article-title":"Prognosis of Severe Asymptomatic Aortic Stenosis with and without Surgery","volume":"108","author":"Campo","year":"2019","journal-title":"Ann. Thorac. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1161\/01.CIR.0000047200.36165.B8","article-title":"Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: First human case description","volume":"106","author":"Cribier","year":"2002","journal-title":"Circulation"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1056\/NEJMoa1514616","article-title":"Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients","volume":"374","author":"Leon","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1056\/NEJMoa1814052","article-title":"Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients","volume":"380","author":"Mack","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJMoa1816885","article-title":"Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients","volume":"380","author":"Popma","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_8","first-page":"2936513","article-title":"Transcatheter Aortic Valve Implantation in an Extremely Tortuous S-Shaped Aorta","volume":"2017","author":"Liu","year":"2017","journal-title":"Case Rep. Cardiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s12928-020-00738-3","article-title":"Transfemoral transcatheter aortic valve implantation for bicuspid aortic stenosis with tortuous aorta after total arch replacement","volume":"37","author":"Hachinohe","year":"2020","journal-title":"Cardiovasc. Interv. Ther."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/gerona\/62.7.731","article-title":"Frailty: An emerging research and clinical paradigm\u2014Issues and controversies","volume":"62","author":"Bergman","year":"2007","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e024163","DOI":"10.1136\/bmjopen-2018-024163","article-title":"Frailty in patients undergoing transcatheter aortic valve implantation: A protocol for a systematic review","volume":"9","author":"Li","year":"2019","journal-title":"BMJ Open"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1016\/j.jacc.2019.09.054","article-title":"Femoral Versus Nonfemoral Peripheral Access for Transcatheter Aortic Valve Replacement","volume":"74","author":"Beurtheret","year":"2019","journal-title":"J. Am. Coll. 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Cardiovasc. Interv."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1111\/1755-5922.12023","article-title":"Predictive factors of vascular complications after transcatheter aortic valve implantation in patients treated with a default percutaneous strategy","volume":"31","author":"Vavuranakis","year":"2013","journal-title":"Cardiovasc. Ther."},{"key":"ref_17","first-page":"5402","article-title":"Meta-analysis of the impact on early and late mortality of TAVI compared to surgical aortic valve replacement in high and low- intermediate surgical risk patients","volume":"23","author":"Sergi","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"234","DOI":"10.23736\/S0025-7826.19.03531-2","article-title":"Inflammation, oxidative stress and gene expression: The postprandial approach in professional soccer players to reduce the risk of muscle injuries and early atherosclerosis","volume":"72","author":"Perrone","year":"2019","journal-title":"Med. Sport"},{"key":"ref_19","first-page":"90","article-title":"Buddy wire technique for successful transfemoral transcatheter aortic valve implantation through an extremely tortuous abdominal aorta: A basic technique in Asian patients?","volume":"3","author":"Naganuma","year":"2017","journal-title":"AsiaIntervention"}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/8\/4763\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:54:10Z","timestamp":1760136850000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/8\/4763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,14]]},"references-count":19,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022,4]]}},"alternative-id":["ijerph19084763"],"URL":"https:\/\/doi.org\/10.3390\/ijerph19084763","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,14]]}}}