{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:05:16Z","timestamp":1791889516300,"version":"4.3.4"},"reference-count":41,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Regenerative medicine combines elements of tissue engineering and molecular biology aiming to support the regeneration and repair processes of damaged tissues, cells and organs. The most commonly used preparation in regenerative medicine is platelet rich plasma (PRP) containing numerous growth factors present in platelet granularities. This therapy is increasingly used in various fields of medicine. This article is a review of literature on the use of PRP in gynecology and obstetrics. There is no doubt that the released growth factors and proteins have a beneficial effect on wound healing and regeneration processes. So far, its widest application is in reproductive medicine, especially in cases of thin endometrium, Asherman\u2019s syndrome, or premature ovarian failure (POF) but also in wound healing and lower urinary tract symptoms (LUTS), such as urinary incontinence or recurrent genitourinary fistula auxiliary treatment. Further research is, however, needed to confirm the effectiveness and the possibility of its application in many other disorders.<\/jats:p>","DOI":"10.3390\/ijerph19095284","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T11:45:55Z","timestamp":1650973555000},"page":"5284","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Platelet Rich Plasma in Gynecology\u2014Discovering Undiscovered\u2014Review"],"prefix":"10.3390","volume":"19","author":[{"given":"Dominika","family":"Streit-Cie\u0107kiewicz","sequence":"first","affiliation":[{"name":"2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8422-5594","authenticated-orcid":false,"given":"Aleksandra","family":"Ko\u0142ody\u0144ska","sequence":"additional","affiliation":[{"name":"2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Futyma-G\u0105bka","sequence":"additional","affiliation":[{"name":"Department of Dental and Maxillofacial Radiology, Medical University of Lublin, ul. Chod\u017aki 6, 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5311-3450","authenticated-orcid":false,"given":"Magdalena","family":"Grzybowska","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Gynecologic Oncology and Gynecologic Endocrinology, Medical University of Gda\u0144sk, Smoluchowskiego 17, 80-214 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8502-3030","authenticated-orcid":false,"given":"Jakub","family":"Go\u0142acki","sequence":"additional","affiliation":[{"name":"2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7864-666X","authenticated-orcid":false,"given":"Konrad","family":"Futyma","sequence":"additional","affiliation":[{"name":"2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1159\/000477353","article-title":"A review of platelet-rich plasma: History, biology, mechanism of action, and classification","volume":"1","author":"Alves","year":"2018","journal-title":"Skin. 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