{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:42:16Z","timestamp":1784594536267,"version":"3.55.0"},"reference-count":59,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T00:00:00Z","timestamp":1651190400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III and co-funded by the European Union (ERDF\/ESF, \u201cInvesting in your future\u201d and \u201cRecovery, Transformation and Resilience Plan\u201d), Research groups (RICAPPS), Government of Castilla y Le\u00f3n and intensification program","award":["RD21\/0016\/0010, GRS 1193\/B\/15, GRS 1821\/B\/18, INT\/M\/08\/9, INT\/M\/9\/19\/INT\/M\/14\/19"],"award-info":[{"award-number":["RD21\/0016\/0010, GRS 1193\/B\/15, GRS 1821\/B\/18, INT\/M\/08\/9, INT\/M\/9\/19\/INT\/M\/14\/19"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Sedentary behaviour is associated with a greater predisposition to developing cardiovascular diseases. The aim of the study was to analyse the relationship between sedentary time and early vascular ageing. A total of 501 participants (49.70% men) were recruited through random sampling stratified by age group and sex. Vascular ageing was evaluated considering three criteria: (1) the vascular ageing index (VAI); (2) the carotid\u2013femoral pulse wave velocity (cfPWV) 10th and 90th percentiles of the reference values in the European population by age; and (3) the Framingham\u2019s heart age. The carotid intima\u2013media thickness was measured using a Sonosite Micromaxx ultrasound, the presence of peripheral artery disease was assessed by calculating the ankle\u2013brachial index using a VaSera VS-1500, and the cfPWV was measured with a SphygmoCor\u00ae device. Weekly sedentary hours were evaluated through a sitting time questionnaire. The average age of the population was 55.90 \u00b1 14.24 years. The men spent more hours sitting per week (47.6 \u00b1 16.6 vs. 36.8 \u00b1 17.3 h\/W), at work (16.7 \u00b1 16.2 vs. 9.73 \u00b1 14.9 h\/W), and watching TV (21.6 \u00b1 12.5 vs. 18.7 \u00b1 11.9 h\/W). In the logistic regression analysis, the individuals with early vascular aging (EVA), with respect to those with healthy vascular aging (HVA), spent more hours sitting per week (OR = 1.03 vs. OR = 1.02; p &lt; 0.05) and watching TV (OR = 1.03 vs. OR = 1.03; p &lt; 0.05), using the criteria of the European guideline and VAI, and more hours sitting when commuting (OR = 1.04; p &lt; 0.05), using Framingham\u2019s heart age to define EVA. The results of this study indicate that sedentary time is associated with early vascular ageing. Therefore, reducing sedentary time would improve vascular health.<\/jats:p>","DOI":"10.3390\/ijerph19095450","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T16:49:57Z","timestamp":1651250997000},"page":"5450","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sedentary Behaviour and Its Relationship with Early Vascular Ageing in the General Spanish Population: A Cross-Sectional Study"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0311-898X","authenticated-orcid":false,"given":"In\u00e9s","family":"Llamas-Ramos","sequence":"first","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"},{"name":"Department of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain"},{"name":"Health Service of Castilla and Leon (SACyL), 37005 Salamanca, Spain"},{"name":"University Hospital of Salamanca, 37007 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5606-261X","authenticated-orcid":false,"given":"Roc\u00edo","family":"Llamas-Ramos","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"},{"name":"Department of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5816-4070","authenticated-orcid":false,"given":"Rosario","family":"Alonso-Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"},{"name":"Department of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8663-9339","authenticated-orcid":false,"given":"Leticia","family":"G\u00f3mez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaya","family":"Tamayo-Morales","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6571-9556","authenticated-orcid":false,"given":"Cristina","family":"Lugones-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3667-7155","authenticated-orcid":false,"given":"Emiliano","family":"Rodr\u00edguez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"},{"name":"Health Service of Castilla and Leon (SACyL), 37005 Salamanca, Spain"},{"name":"Department of Medicine, Universidad de Salamanca, 37007 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Garc\u00eda-Ortiz","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"},{"name":"Health Service of Castilla and Leon (SACyL), 37005 Salamanca, Spain"},{"name":"Department of Biomedical and Diagnostic Sciences, Universidad de Salamanca, 37007 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0133-6123","authenticated-orcid":false,"given":"Manuel A.","family":"G\u00f3mez-Marcos","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), Primary Care Research Unit of Salamanca (APISAL), 37005 Salamanca, Spain"},{"name":"Health Service of Castilla and Leon (SACyL), 37005 Salamanca, Spain"},{"name":"Department of Medicine, Universidad de Salamanca, 37007 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,29]]},"reference":[{"key":"ref_1","first-page":"233","article-title":"Sedentary lifestyle a disease from xxi century","volume":"31","author":"Rodulfo","year":"2019","journal-title":"Clin. 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