{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:30:35Z","timestamp":1789468235622,"version":"build-2803163510"},"reference-count":44,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>After anterior cruciate ligament reconstruction (ACLR), a progressive process is followed from rehabilitation to the return to sport including a crucial step known as the return to running. Return to running (RTR) can be predicted by an isokinetic knee strength assessment at 4 months post-surgery. All patients who had primarily undergone ACLR with a hamstring autograft procedure between 2010 and 2020 were included in this study. Four months after surgery, patients were evaluated using an isokinetic knee strength test. Patients were monitored until the 6th month post-surgery to see if they had returned to running. Comparisons were carried out between the two groups\u2014the RTR and the no-RTR. A multivariate logistic regression analysis was used to predict the RTR status from explicative parameters. Receiver Operating Characteristic (ROC) curves were established to identify cutoffs with their characteristics. A total of 413 patients were included and 63.2% returned to running at 4 months post-surgery. The mean Lysholm score, knee complication rate, and isokinetic parameters were statistically different between both groups. Using a multivariate logistic regression model and ROC curves, the best isokinetic parameter to assist with the decision to allow an RTR was the quadriceps limb symmetry index at 60\u00b0\/s with a cutoff of 65%. The hamstring LSI at 180\u00b0\/s could be added (cutoff of 80%) to slightly increase the prediction of an RTR. Quadriceps strength normalized to body weight at 60\u00b0\/s is a useful parameter (cutoff: 1.60 Nm\/kg) but measurements on both sides are necessary. Isokinetic parameters are objective parameters to allow a return to running at 4 months after ACLR with a hamstring procedure.<\/jats:p>","DOI":"10.3390\/ijerph19148245","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T09:41:10Z","timestamp":1657100470000},"page":"8245","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Relevant Strength Parameters to Allow Return to Running after Primary Anterior Cruciate Ligament Reconstruction with Hamstring Tendon Autograft"],"prefix":"10.3390","volume":"19","author":[{"given":"J\u00e9r\u00f4me","family":"Grondin","sequence":"first","affiliation":[{"name":"Service de M\u00e9decine Physique et R\u00e9adapatation Locomotrice et Respiratoire, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"Service de M\u00e9decine du Sport, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6563-8895","authenticated-orcid":false,"given":"Vincent","family":"Crenn","sequence":"additional","affiliation":[{"name":"Clinique Chirurgicale Orthop\u00e9dique et Traumatologique, CHU Nantes, Nantes Universit\u00e9, 44000 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0303-7293","authenticated-orcid":false,"given":"Marie","family":"Gernigon","sequence":"additional","affiliation":[{"name":"Complexit\u00e9, Innovation, Activit\u00e9s Motrices et Sportives\u2014CIAMS, Universit\u00e9 Paris-Saclay, CEDEX, 91405 Orsay, France"},{"name":"Complexit\u00e9, Innovation, Activit\u00e9s Motrices et Sportives\u2014CIAMS, Universit\u00e9 d\u2019Orl\u00e9ans, 45067 Orl\u00e9ans, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonis","family":"Quinette","sequence":"additional","affiliation":[{"name":"Clinique Chirurgicale Orthop\u00e9dique et Traumatologique, CHU Nantes, Nantes Universit\u00e9, 44000 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastien","family":"Louguet","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Physique et R\u00e9adapatation Locomotrice et Respiratoire, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"Service de M\u00e9decine du Sport, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Menu","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Physique et R\u00e9adapatation Locomotrice et Respiratoire, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"Service de M\u00e9decine du Sport, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"IRMS\u2014Institut R\u00e9gional de M\u00e9decine du Sport, 44093 Nantes, France"},{"name":"Inserm UMR 1229, Regenerative Medicine and Skeleton, RMeS, Nantes Universit\u00e9, 44042 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8139-814X","authenticated-orcid":false,"given":"Alban","family":"Fouasson-Chailloux","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Physique et R\u00e9adapatation Locomotrice et Respiratoire, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"Service de M\u00e9decine du Sport, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"IRMS\u2014Institut R\u00e9gional de M\u00e9decine du Sport, 44093 Nantes, France"},{"name":"Inserm UMR 1229, Regenerative Medicine and Skeleton, RMeS, Nantes Universit\u00e9, 44042 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Dauty","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Physique et R\u00e9adapatation Locomotrice et Respiratoire, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"Service de M\u00e9decine du Sport, CHU Nantes, Nantes Universit\u00e9, 44093 Nantes, France"},{"name":"IRMS\u2014Institut R\u00e9gional de M\u00e9decine du Sport, 44093 Nantes, France"},{"name":"Inserm UMR 1229, Regenerative Medicine and Skeleton, RMeS, Nantes Universit\u00e9, 44042 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.csm.2007.06.003","article-title":"Allograft Safety in Anterior Cruciate Ligament Reconstruction","volume":"26","author":"Cohen","year":"2007","journal-title":"Clin. 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