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Despite the potential of e-cigarettes to support cigarette cessation, their use increases health risks and risk for addiction, particularly in young people. Various federal, state, and local laws have impacted tobacco retail in general and e-cigarettes in particular. In the US, 2019\u20132020 federal laws increased in the minimum legal sales age for tobacco to 21 and banned flavored cartridge-based e-cigarettes. Many states and localities were early adopters of Tobacco 21 and implemented more comprehensive flavor restrictions than the federal ban. Meanwhile, cannabis retail is increasingly being legalized in the US\u2014while cannabis-based product regulation has notable gaps at the federal, state, and local levels. These regulatory complexities have impacted specialized retailers selling e-cigarettes, including \u201cvape shops\u201d that exclusively sell e-cigarettes, \u201csmoke shops\u201d that sell e-cigarettes and other tobacco (and potentially CBD\/THC and other un- or under-regulated products), and online retail. This commentary outlines public health concerns related to: (1) youth access; (2) consumer exposure to a broader range of tobacco products and marketing in retail settings where they may seek products to aid in cigarette cessation (i.e., such broad product exposure could hinder cessation attempts); (3) consumer exposure to un-\/under-regulated products (e.g., delta-8-THC, kratom); and (4) federal, state, and local regulations being undermined by consumer access to prohibited products online and via the mail. These concerns underscore the need for ongoing surveillance of how retailers and consumers respond to regulations.<\/jats:p>","DOI":"10.3390\/ijerph19148518","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T20:52:41Z","timestamp":1657659161000},"page":"8518","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Reshaping of the E-Cigarette Retail Environment: Its Evolution and Public Health Concerns"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8931-1961","authenticated-orcid":false,"given":"Carla J.","family":"Berg","sequence":"first","affiliation":[{"name":"Department of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, 950 New Hampshire Avenue, Washington, DC 20052, USA"},{"name":"George Washington Cancer Center, George Washington University, 800 22nd Street NW, #7000C, Washington, DC 20052, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Melena","sequence":"additional","affiliation":[{"name":"San Fernando Valley Partnership, Inc., 1131 Celis Street, San Fernando, CA 91340, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedner D.","family":"Wittman","sequence":"additional","affiliation":[{"name":"CLEW Associates, 950 Gilman Street, Berkeley, CA 94710, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Robles","sequence":"additional","affiliation":[{"name":"San Fernando Valley Partnership, Inc., 1131 Celis Street, San Fernando, CA 91340, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Henriksen","sequence":"additional","affiliation":[{"name":"Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, 3180 Porter Drive, Suite 125, Palo Alto, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,12]]},"reference":[{"key":"ref_1","unstructured":"Grand View Research (2021, November 06). 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