{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:35:40Z","timestamp":1765233340465,"version":"build-2065373602"},"reference-count":69,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Public Healthcare System (Andalusian Regional Ministry of Health and Families)","award":["PI-0107-2020"],"award-info":[{"award-number":["PI-0107-2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Background: There is currently a global consensus that the quality of comprehensive care for acutely hospitalised elderly people should include addressing functionality and mobility, cognitive status, prevention of pressure ulcers, urinary incontinence, falls and delirium, as well as pain control and medication-related problems. The aim of this study is to develop and validate a clinical prediction rule for multimorbid patients admitted to an acute care hospital unit for any of the five adverse events included in our vulnerability pentad: falls, pressure ulcers, urinary incontinence, pain and delirium. (2) Methods: Longitudinal analytical clinimetric study, with two cohorts. The study population will consist of multimorbid patients hospitalised for acute care, referred from the Emergency Room. A clinical prediction rule will be proposed, incorporating predictive factors of these five adverse outcomes described. This study has received funding, awarded in November 2020 (PI-0107-2020), and was approved in October 2019 by the Research Ethics Committee \u2033Costa del Sol\u2033. (3) Conclusions: Preventing adverse events in hospitalised patients is particularly important for those with multimorbidity. By applying a clinical prediction rule to detect specific risks, an estimate can be obtained of their probability of occurrence.<\/jats:p>","DOI":"10.3390\/ijerph19148581","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:17:10Z","timestamp":1657844230000},"page":"8581","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Development of a Clinical Prediction Rule for Adverse Events in Multimorbid Patients in Emergency and Hospitalisation"],"prefix":"10.3390","volume":"19","author":[{"given":"Marta","family":"Morales-Puerto","sequence":"first","affiliation":[{"name":"Hospital Costa del Sol, Servicio Andaluz de Salud, Autov\u00eda A7, Km, 187 Marbella, 29603 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Ruiz-D\u00edaz","sequence":"additional","affiliation":[{"name":"Hospital Costa del Sol, Servicio Andaluz de Salud, Autov\u00eda A7, Km, 187 Marbella, 29603 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0399-9561","authenticated-orcid":false,"given":"Marta","family":"Aranda-Gallardo","sequence":"additional","affiliation":[{"name":"Hospital Costa del Sol, Servicio Andaluz de Salud, Autov\u00eda A7, Km, 187 Marbella, 29603 M\u00e1laga, Spain"},{"name":"Department of Nursing, Faculty of Health Sciences, Universidad de M\u00e1laga, C\/Arquitecto Francisco Pe\u00f1alosa 3, 29017 M\u00e1laga, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), 29590 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7911-7487","authenticated-orcid":false,"given":"Jos\u00e9 Miguel","family":"Morales-Asencio","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, Universidad de M\u00e1laga, C\/Arquitecto Francisco Pe\u00f1alosa 3, 29017 M\u00e1laga, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), 29590 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Purificaci\u00f3n","family":"Alcal\u00e1-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Hospital Costa del Sol, Servicio Andaluz de Salud, Autov\u00eda A7, Km, 187 Marbella, 29603 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7890-6417","authenticated-orcid":false,"given":"Jos\u00e9 Antonio","family":"Rodr\u00edguez-Montalvo","sequence":"additional","affiliation":[{"name":"Hospital Costa del Sol, Servicio Andaluz de Salud, Autov\u00eda A7, Km, 187 Marbella, 29603 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1lvaro","family":"Le\u00f3n-Campos","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, Universidad de M\u00e1laga, C\/Arquitecto Francisco Pe\u00f1alosa 3, 29017 M\u00e1laga, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), 29590 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3913-3850","authenticated-orcid":false,"given":"Silvia","family":"Garc\u00eda-Mayor","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Health Sciences, Universidad de M\u00e1laga, C\/Arquitecto Francisco Pe\u00f1alosa 3, 29017 M\u00e1laga, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), 29590 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1906-3568","authenticated-orcid":false,"given":"Jos\u00e9 Carlos","family":"Canca-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Hospital Costa del Sol, Servicio Andaluz de Salud, Autov\u00eda A7, Km, 187 Marbella, 29603 M\u00e1laga, Spain"},{"name":"Department of Nursing, Faculty of Health Sciences, Universidad de M\u00e1laga, C\/Arquitecto Francisco Pe\u00f1alosa 3, 29017 M\u00e1laga, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), 29590 M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/j.ijnurstu.2009.06.015","article-title":"Cascade Iatrogenesis: Factors Leading to the Development of Adverse Events in Hospitalized Older Adults","volume":"46","author":"Thornlow","year":"2009","journal-title":"Int. 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