{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T19:23:26Z","timestamp":1779391406688,"version":"3.53.1"},"reference-count":49,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:00:00Z","timestamp":1658707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: The unprotected calcified Left Main disease represents a high-risk subset for percutaneous coronary intervention (PCI), and it is associated with a higher number of periprocedural complications and an increased rate of in-stent thrombosis and restenosis. Adequate lesion preparation plays a crucial role in achieving a favorable PCI outcome. Rotational Atherectomy (RA) is a well-established plaque-modifying method; nevertheless, the data regarding the effectiveness of RA in LM diseases is scarce. Recently, the novel ShockWave-Intravascular-Lithotripsy(S-IVL) device has been introduced to the PCI armamentarium in order to modify the calcified plaque. Methods: We performed a retrospective evaluation of 44 consecutive subjects who underwent the LM-PCI, and who were supported by either the RA or S-IVL. Results: The Rota group consisted of 29 patients with a mean syntax score of 28.0 \u00b1 7.5. The S-IVL group was composed of 15 subjects with a syntax score of 23.3 \u00b1 13.0 There were no statistical differences regarding MACE between the RA and Shockwave arms of the in-hospital group (10.3% vs. 6.7%), or in the six month (17.2% vs. 13.3%) follow-up group. Conclusions: RA and S-IVL could be safe and effective therapeutic strategies for calcified LM disease. Further studies with a higher number of participants and longer follow-up times are warranted to establish the potential benefits of RA and S-IVL for the management of LM stenosis.<\/jats:p>","DOI":"10.3390\/ijerph19159011","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T04:52:47Z","timestamp":1658724767000},"page":"9011","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Intravascular Lithotripsy as a Novel Treatment Method for Calcified Unprotected Left Main Diseases\u2014Comparison to Rotational Atherectomy\u2014Short-Term Outcomes"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0963-2712","authenticated-orcid":false,"given":"Piotr","family":"Rola","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences and Physical Culture, Witelon Collegium State University, 59-220 Legnica, Poland"},{"name":"Department of Cardiology, Provincial Specialized Hospital, 59-220 Legnica, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6670-6044","authenticated-orcid":false,"given":"Jan Jakub","family":"Kulczycki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3104-7728","authenticated-orcid":false,"given":"Adrian","family":"W\u0142odarczak","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences and Physical Culture, Witelon Collegium State University, 59-220 Legnica, Poland"},{"name":"Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9112-8012","authenticated-orcid":false,"given":"Mateusz","family":"Barycki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Provincial Specialized Hospital, 59-220 Legnica, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9886-0310","authenticated-orcid":false,"given":"Szymon","family":"W\u0142odarczak","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Szudrowicz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0141ukasz","family":"Furtan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Provincial Specialized Hospital, 59-220 Legnica, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artur","family":"Jastrz\u0119bski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maciej","family":"P\u0119cherzewski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2630-5016","authenticated-orcid":false,"given":"Maciej","family":"Lesiak","sequence":"additional","affiliation":[{"name":"1st Department of Cardiology, University of Medical Sciences, 61-848 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5472-028X","authenticated-orcid":false,"given":"Adrian","family":"Doroszko","sequence":"additional","affiliation":[{"name":"Clinical Department of Internal Medicine and Occupational Diseases, Hypertension and Clinical Oncology, Faculty of Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e007822","DOI":"10.1161\/CIRCINTERVENTIONS.119.007822","article-title":"Risk factors and long-term clinical outcomes of second-generation drug-eluting stent thrombosis","volume":"12","author":"Kuramitsu","year":"2019","journal-title":"Circ. 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