{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T06:50:25Z","timestamp":1762066225152,"version":"build-2065373602"},"reference-count":46,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2022,9,4]],"date-time":"2022-09-04T00:00:00Z","timestamp":1662249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Acad\u00e9mie de Recherche et d\u2019Enseignement Sup\u00e9rieu"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Objectives: to determine modifiable risk factors of exacerbations in chronic respiratory diseases with airways obstruction (i.e., asthma and COPD) in southern Vietnam. Methods: an environmental and health-related behavioural questionnaire was submitted to patients with both chronic respiratory symptoms and airways obstruction. An exacerbation was defined as any acute worsening in clinical symptoms requiring a change in treatment, in a patient receiving prophylactic therapy. Results: 235 patients were evaluated, including 131 (56%) chronic obstructive pulmonary disease (COPD) and 104 (44%) asthmatics. There were 75% males and 69% smokers. Occupational exposure accounted for 66%, mainly among construction and industry workers. Smoking was associated with more severe airways obstruction. Respiratory exacerbations were reported in 56\/235 patients (24%). The risk of exacerbation was increased in patients with a lower education level, exposure to occupational pollutants, cumulative smoking \u2265 20 pack year, housing space &lt; 10 m2, and poorly ventilated housing. Based on multivariate analysis, the risk of exacerbation remained significantly higher among patients with occupational exposure and low housing space per person. Conclusions: besides smoking cessation, more supportive policies, including improvement of occupational environment and housing design for better ventilation, are needed to prevent the severity of chronic respiratory diseases in Vietnam.<\/jats:p>","DOI":"10.3390\/ijerph191711088","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T05:17:23Z","timestamp":1662441443000},"page":"11088","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Identification of Modifiable Risk Factors of Exacerbations in Chronic Respiratory Diseases with Airways Obstruction in Vietnam"],"prefix":"10.3390","volume":"19","author":[{"given":"Thuy","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Family Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City 740500, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoa","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City 740500, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thanh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City 740500, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duc","family":"Vo","sequence":"additional","affiliation":[{"name":"Nguyen Tri Phuong Hospital, Ho Chi Minh City 740500, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Godin","sequence":"additional","affiliation":[{"name":"School of Public Health, Universit\u00e9 Libre de Bruxelles (ULB), 1050 Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1528-1277","authenticated-orcid":false,"given":"Olivier","family":"Michel","sequence":"additional","affiliation":[{"name":"Clinic of Immuno-Allergology, CHU Brugmann, Universit\u00e9 Libre de Bruxelles (ULB), 4 Place A-Van Gehuchten, 1020 Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S2213-2600(20)30157-0","article-title":"Chronic respiratory diseases: A global view","volume":"8","author":"Labaki","year":"2020","journal-title":"Lancet Respir. 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