{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T14:18:09Z","timestamp":1775744289086,"version":"3.50.1"},"reference-count":42,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:00:00Z","timestamp":1663113600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Studies on the survival rate of implant overdentures in medically compromised patients are limited because most studies exclude patients with systemic diseases affecting implant prognosis. This retrospective study aimed to evaluate the survival rate and clinical outcomes of dental implants used for overdentures in medically compromised patients. A total of 20 patients (9 men, 11 women; mean age: 67.55 \u00b1 6.84 years, range: 53\u201381 years) were included. Fourteen patients had more than two systemic diseases, and nine patients had more than three systemic diseases. The mean follow-up period was 39.05 months. Of the 60 implants, 2 failed, resulting in an implant survival rate of 96.6%. No statistical differences were found in implant survival rates according to sex, age, implant diameter, restored arch, or opposing dentition (p &gt; 0.05). A significant difference in mean marginal bone loss (MBL) was noted for restoring the arch (p = 0.022) and opposing dentition (p = 0.036). Implants placed in the mandible and with opposing removable partial dentures and complete dentures showed lower mean MBL. No significant differences in implant MBL were observed in terms of age, sex, or implant diameter (p &gt; 0.05). Favorable clinical outcomes can be expected from implant overdentures using two or four implants in edentulous patients with systemic diseases by ensuring that the patients have a sufficient healing period and regular checkups.<\/jats:p>","DOI":"10.3390\/ijerph191811571","type":"journal-article","created":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T20:50:45Z","timestamp":1663188645000},"page":"11571","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Survival Rates and Clinical Outcomes of Implant Overdentures in Old and Medically Compromised Patients"],"prefix":"10.3390","volume":"19","author":[{"given":"So-Hyun","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dentistry, Inha University Hospital, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon 22332, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0155-7746","authenticated-orcid":false,"given":"Nam-Sik","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Inha University Hospital, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon 22332, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5418-1052","authenticated-orcid":false,"given":"Hyo-Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Ulsan University Hospital, University of Ulsan College of Medicine, 877 Bangeojinsunwhando-ro, Dong-gu, Ulsan 44033, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,14]]},"reference":[{"key":"ref_1","unstructured":"Statistics Korea (2022, August 12). Population Projections for Korea (2020~2070), Available online: http:\/\/kostat.go.kr\/portal\/eng\/pressReleases\/8\/8\/index.board?bmode=read&bSeq=&aSeq=416209&pageNo=1&rowNum=10&navCount=10&currPg=&searchInfo=&sTarget=title&sTxt=."},{"key":"ref_2","unstructured":"Ministry of Health and Welfare (2022, August 12). National Survey of Older Koreans (2020), Available online: http:\/\/www.mohw.go.kr\/react\/jb\/sjb030301vw.jsp?PAR_MENU_ID=03&MENU_ID=032901&CONT_SEQ=366496&page=1."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"248","DOI":"10.5051\/jpis.2019.49.4.248","article-title":"The socioeconomic impact of Korean dental health insurance policy on the elderly: A nationwide cohort study in South Korea","volume":"49","author":"Seo","year":"2019","journal-title":"J. Periodontal Implant Sci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/ger.12085","article-title":"Epidemiology of oral health conditions in older people","volume":"31","author":"Thomson","year":"2014","journal-title":"Gerodontology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/cid.12772","article-title":"Mandibular implant-supported overdentures in (frail) elderly: Aprospective study with 20-year follow-up","volume":"21","author":"Bakker","year":"2019","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1007\/s00784-016-1746-y","article-title":"Implant placement under existing removable dental prostheses and its effect on masticatory performance","volume":"20","author":"Wolfart","year":"2016","journal-title":"Clin. Oral Investig."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1111\/j.1741-2358.2009.00314.x","article-title":"Oral implants in dependent elderly persons: Blessing or burden?","volume":"28","author":"Visser","year":"2011","journal-title":"Gerodontology"},{"key":"ref_8","first-page":"601","article-title":"The McGill consensus statement on overdentures. Mandibular two-implant overdentures as first choice standard of care for edentulous patients. Montreal, Quebec, 24\u201325 May 2002","volume":"17","author":"Feine","year":"2002","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jdent.2011.08.017","article-title":"Two implant retained overdentures\u2013a review of the literature supporting the McGill and York consensus statements","volume":"40","author":"Thomason","year":"2012","journal-title":"J. Dent."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/clr.12630","article-title":"EAO consensus conference: Economic evaluation of implant-supported prostheses","volume":"26","author":"Beikler","year":"2015","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/odi.12762","article-title":"The medically compromised patient: Are dental implants a feasible option?","volume":"24","author":"Vissink","year":"2018","journal-title":"Oral Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/clr.12531","article-title":"A systematic review and meta-analysis of removable and fixed implant-supported prostheses in edentulous jaws: Post-loading implant loss","volume":"27","author":"Kern","year":"2016","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/ID.0b013e3181676059","article-title":"Implant success, survival, and failure: The International Congress of Oral Implantologists (ICOI) Pisa Consensus Conference","volume":"17","author":"Misch","year":"2008","journal-title":"Implant Dent."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/adj.12282","article-title":"Implants for the ageing population","volume":"60","author":"Dudley","year":"2015","journal-title":"Aust. Dent. J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/clr.13288","article-title":"Effect of advanced age and\/or systemic medical conditions on dental implant survival: A systematic review and meta-analysis","volume":"29","author":"Schimmel","year":"2018","journal-title":"Clin. Oral Implants Res."},{"key":"ref_16","unstructured":"World Health Organization (2022, August 12). Definition, Diagnosis and Classification of Diabetes Mellitus and Its Complications: Report of a WHO Consultation. Part 1, Diagnosis and Classification of Diabetes Mellitus. Available online: https:\/\/apps.who.int\/iris\/handle\/10665\/66040."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1097\/ID.0000000000000478","article-title":"Survival analysis of implant in patients with diabetes mellitus: A systematic review","volume":"25","author":"Annibali","year":"2016","journal-title":"Implant Dent."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Sghaireen, M.G., Alduraywish, A.A., Srivastava, K.C., Shrivastava, D., Patil, S.R., Al Habib, S., Hamza, M., Ab Rahman, S., Lynch, E., and Alam, M.K. (2020). Comparative evaluation of dental implant failure among healthy and well-controlled diabetic patients\u2014A 3-year retrospective study. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17145253"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"s35","DOI":"10.11607\/jomi.19suppl.g3","article-title":"The effects of systemic diseases and medications on implant osseointegration: A systematic review","volume":"34","author":"Aghaloo","year":"2019","journal-title":"Int. J. Oral Maxillofac. Implant."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.tem.2020.05.005","article-title":"Obesity\/metabolic syndrome and diabetes mellitus on periimplantitis","volume":"31","author":"Bonfante","year":"2020","journal-title":"Trends Endocrinol. Metab."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"103436","DOI":"10.1016\/j.jdent.2020.103436","article-title":"Clinical, histological, and nanomechanical parameters of implants placed in healthy and metabolically compromised patients","volume":"100","author":"Granato","year":"2020","journal-title":"J. Dent."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1007\/s00784-016-1937-6","article-title":"Dental implants in medically complex patients\u2014A retrospective study","volume":"21","author":"Manor","year":"2017","journal-title":"Clin. Oral Investig."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.11607\/jomi.2014suppl.g1.3","article-title":"Systematic review on success of narrow-diameter dental implants","volume":"29","author":"Klein","year":"2014","journal-title":"Int. J. Oral Maxillofac. Implant."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1532-849X.2009.00453.x","article-title":"Implant-bone interface stress distribution in immediately loaded implants of different diameters: A three-dimensional finite element analysis","volume":"18","author":"Ding","year":"2009","journal-title":"J. Prosthodont."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0022-3913(08)60259-0","article-title":"The influence of implant diameter and length on stress distribution of osseointegrated implants related to crestal bone geometry: A three-dimensional finite element analysis","volume":"100","author":"Baggi","year":"2008","journal-title":"J. Prosthet. Dent."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1741-2358.2000.00045.x","article-title":"Success of dental implants in elderly people\u2014A literature review","volume":"17","year":"2000","journal-title":"Gerodontology"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jdent.2012.12.008","article-title":"Dental implants in the medically compromised patient","volume":"41","author":"Diz","year":"2013","journal-title":"J. Dent."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/jgs.15175","article-title":"Influence of poor oral health on physical frailty: A population-based cohort study of older British men","volume":"66","author":"Ramsay","year":"2018","journal-title":"J. Am. Geriatr. Soc."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/ageing\/26.6.445","article-title":"Influence of dental status on dietary intake and survival in community-dwelling elderly subjects","volume":"26","author":"Appollonio","year":"1997","journal-title":"Age Ageing"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/cid.12984","article-title":"General health status of Dutch elderly receiving implant-retained overdentures: A 9-year big data cross-sectional study","volume":"23","author":"Bakker","year":"2021","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jpor.2017.12.007","article-title":"Effects of tooth loss on brain structure: A voxel-based morphometry study","volume":"62","author":"Kobayashi","year":"2018","journal-title":"J. Prosthodont. Res"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Oh, B., Han, D.H., Han, K.T., Liu, X., Ukken, J., Chang, C., Dounis, K., and Yoo, J.W. (2018). Association between residual teeth number in later life and incidence of dementia: A systematic review and meta-analysis. BMC Geriatr., 18.","DOI":"10.1186\/s12877-018-0729-z"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"e752","DOI":"10.1111\/jopr.12943","article-title":"Implant placement under existing removable dental prostheses and the effect on follow-up and prosthetic maintenance","volume":"28","author":"Marotti","year":"2019","journal-title":"J. Prosthodont."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/cid.12351","article-title":"Influence of age on clinical performance of mandibular two-implant overdentures: A 10-year prospective comparative study","volume":"18","author":"Hoeksema","year":"2016","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1111\/cid.12190","article-title":"Implant tooth-supported removable partial denture with at least 15-year long-term follow-up","volume":"17","author":"Mijiritsky","year":"2015","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Yoo, S.Y., Kim, S.K., Heo, S.J., Koak, J.Y., and Jeon, H.R. (2021). Clinical performance of implant crown retained removable partial dentures for mandibular edentulism-a retrospective study. J. Clin. Med., 10.","DOI":"10.3390\/jcm10102170"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Nitschke, I., Wendland, A., Weber, S., Jockusch, J., Lethaus, B., and Hahnel, S. (2021). Considerations for the prosthetic dental treatment of geriatric patients in Germany. J. Clin. Med., 10.","DOI":"10.3390\/jcm10020304"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1034\/j.1600-0501.2003.140117.x","article-title":"Within-subject comparisons of maxillary fixed and removable implant prostheses: Patient satisfaction and choice of prosthesis","volume":"14","author":"Heydecke","year":"2003","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpor.2017.06.004","article-title":"A systematic review of studies comparing conventional complete denture and implant retained overdenture","volume":"62","author":"Kutkut","year":"2018","journal-title":"J. Prosthodont. Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1111\/j.1365-2842.2011.02220.x","article-title":"To splint or not to splint oral implants in the implant-supported overdenture therapy? A systematic literature review","volume":"38","author":"Stoumpis","year":"2011","journal-title":"J. Oral Rehabil."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.prosdent.2018.10.014","article-title":"Retrospective cohort analysis of maxillary overdentures retained by unsplinted implants","volume":"122","author":"Anadioti","year":"2019","journal-title":"J. Prosthet. Dent."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Cosola, S., Marconcini, S., Boccuzzi, M., Menchini Fabris, G.B., Covani, U., Pe\u00f1arrocha-Diago, M., and Pe\u00f1arrocha-Oltra, D. (2020). Radiological outcomes of bone-level and tissue-level dental implants: Systematic review. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17186920"}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/18\/11571\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:31:16Z","timestamp":1760142676000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/18\/11571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,14]]},"references-count":42,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2022,9]]}},"alternative-id":["ijerph191811571"],"URL":"https:\/\/doi.org\/10.3390\/ijerph191811571","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,14]]}}}