{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:15:04Z","timestamp":1792005304205,"version":"4.4.0"},"reference-count":35,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Guangxi key research and development project","award":["GXS AB18221010"],"award-info":[{"award-number":["GXS AB18221010"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: This study aims to determine the prevalence of TB among ambulatory people living with HIV in Guangxi Province, which experienced the biggest HIV epidemic in China. Methods: We undertook a longitudinal study in five HIV\/AIDS designated hospitals randomly selected from Guangxi Province; all newly diagnosed HIV\/AIDS outpatients from 2019 to 2021 were screened for TB and interviewed with a questionnaire. Results: A total of 4539 HIV\/AIDS outpatients were enrolled, with 2886 (63.6%) men and 1653 (26.4%) women. The prevalence of TB\/HIV coinfection was 0.8%, with a clear downward trend from 1.3% in 2019 to 0.4% in 2021 (p = 0.0011). The prevalence of LTBI was 24.3%, with no significant differences from 2019 to 2021. The percentages of AIDS, comorbidity, nine symptoms and abnormal chest X-ray of TB were higher than those of the other PLWH. Conclusion: The prevalence of TB among ambulatory people with HIV in Guangxi Province was 14 times higher than the general population, and the annual declined TB prevalence indicated the effectiveness of TB and HIV control and prevention over recent years. The findings proved that symptom screening was insufficient for TB diagnosis and highlighted the importance of systematic TB screening at every visit to a health facility.<\/jats:p>","DOI":"10.3390\/ijerph191912280","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T23:12:12Z","timestamp":1664320332000},"page":"12280","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Tuberculosis among Ambulatory People Living with HIV in Guangxi Province, China: A Longitudinal Study"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3415-6970","authenticated-orcid":false,"given":"Zhezhe","family":"Cui","sequence":"first","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8620-3869","authenticated-orcid":false,"given":"Fei","family":"Huang","sequence":"additional","affiliation":[{"name":"National Center for TB Control and Prevention, China CDC, Beijing 100013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dabin","family":"Liang","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Huang","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huifang","family":"Qin","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Ye","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwen","family":"Huang","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongxing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minying","family":"Huang","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Liang","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengxue","family":"Long","sequence":"additional","affiliation":[{"name":"School of Public Health, Guangxi Medical University, Nanning 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanlin","family":"Zhao","sequence":"additional","affiliation":[{"name":"National Center for TB Control and Prevention, China CDC, Beijing 100013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Lin","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.2174\/1568026621666210916170417","article-title":"\u201cBig Three\u201d Infectious Diseases: Tuberculosis, Malaria and HIV\/AIDS","volume":"21","author":"Makam","year":"2021","journal-title":"Curr. 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