{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:29:17Z","timestamp":1792189757336,"version":"4.4.0"},"reference-count":57,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T00:00:00Z","timestamp":1664928000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"MCIN\/AEI","award":["PID2019-103956RB-I00"],"award-info":[{"award-number":["PID2019-103956RB-I00"]}]},{"name":"MCIN\/AEI","award":["GV\/2021\/174"],"award-info":[{"award-number":["GV\/2021\/174"]}]},{"DOI":"10.13039\/501100003359","name":"Conselleria de Innovaci\u00f3n, Universidades, Ciencia y Sociedad Digital of Generalitat Valenciana (Spain)","doi-asserted-by":"publisher","award":["PID2019-103956RB-I00"],"award-info":[{"award-number":["PID2019-103956RB-I00"]}],"id":[{"id":"10.13039\/501100003359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003359","name":"Conselleria de Innovaci\u00f3n, Universidades, Ciencia y Sociedad Digital of Generalitat Valenciana (Spain)","doi-asserted-by":"publisher","award":["GV\/2021\/174"],"award-info":[{"award-number":["GV\/2021\/174"]}],"id":[{"id":"10.13039\/501100003359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: Transcranial direct current stimulation (tDCS) has emerged as a prevention method or minimizer of the normal cognitive deterioration that occurs during the aging process. tDCS can be used to enhance cognitive functions such as immediate memory, learning, or working memory in healthy subjects. The objective of this study was to analyze the effect of two 20-min sessions of anodal transcranial direct stimulation on immediate memory, learning potential, and working memory in healthy older adults. Methods: A randomized, single-blind, repeated-measures, sham-controlled design was used. The sample is made up of 31 healthy older adults, of whom 16 were in the stimulation group and 15 were in the sham group. The anode was placed on position F7, coinciding with the left dorsolateral prefrontal cortex region, and the cathode was placed on Fp2, the right supraorbital area (rSO). Results: When comparing the results of the treatment group and the sham group, differences were observed in working memory and learning potential; however, no differences in immediate memory were found. Conclusion: The results showed that tDCS is a non-invasive and safe tool to enhance cognitive processes in healthy older adults interested in maintaining some cognitive function.<\/jats:p>","DOI":"10.3390\/ijerph191912716","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T22:19:27Z","timestamp":1665267567000},"page":"12716","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Enhancing Immediate Memory, Potential Learning, and Working Memory with Transcranial Direct Current Stimulation in Healthy Older Adults"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8589-8697","authenticated-orcid":false,"given":"Encarnaci\u00f3n","family":"Satorres","sequence":"first","affiliation":[{"name":"Department of Developmental Psychology, Faculty of Psychology, University of Valencia, Av. Blasco Iba\u00f1ez 21, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6353-6035","authenticated-orcid":false,"given":"Juan C.","family":"Mel\u00e9ndez","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychology, Faculty of Psychology, University of Valencia, Av. Blasco Iba\u00f1ez 21, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Pitarque","sequence":"additional","affiliation":[{"name":"Department of Methodology, Faculty of Psychology, University of Valencia, Av. Blasco Iba\u00f1ez 21, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Real","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychology, Faculty of Psychology, University of Valencia, Av. Blasco Iba\u00f1ez 21, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireia","family":"Abella","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychology, Faculty of Psychology, University of Valencia, Av. Blasco Iba\u00f1ez 21, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Escudero","sequence":"additional","affiliation":[{"name":"Hospital General of Valencia, Av. Tres Cruces, 2, 46014 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.arr.2015.11.004","article-title":"Does transcranial direct current stimulation enhance cognitive and motor functions in the ageing brain? A systematic review and meta-analysis","volume":"25","author":"Summers","year":"2016","journal-title":"Ageing Res. Rev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.brs.2016.04.001","article-title":"Older adults improve on everyday tasks after working memory training and neurostimulation","volume":"9","author":"Stephens","year":"2016","journal-title":"Brain Stimul."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.bandc.2012.02.007","article-title":"Working memory training: Improving intelligence\u2013changing brain activity","volume":"79","year":"2012","journal-title":"Brain Cogn."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.brs.2018.12.977","article-title":"Sham tDCS: A hidden soucre of variability? Reflections for further blinded, controlled trails","volume":"12","author":"Fontenau","year":"2019","journal-title":"Brain Stimul."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.cortex.2016.10.016","article-title":"Limits to tDCS effects in language: Failures to modulate word production in healthy participants with frontal or temporal tDCS","volume":"86","author":"Westwood","year":"2017","journal-title":"Cortex"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1113\/jphysiol.2012.249730","article-title":"Partially non-linear stimulation intensity-dependent effects of direct current stimulation on motor cortex excitability in humans","volume":"591","author":"Batsikadze","year":"2013","journal-title":"J. Physiol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.brs.2011.06.007","article-title":"Transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex modulates declarative memory","volume":"5","author":"Javadi","year":"2012","journal-title":"Brain Stimul."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.brs.2016.04.006","article-title":"A systematic review and meta-analysis of the effects of transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex in healthy and neuropsychiatric samples: Influence of stimulation parameters","volume":"9","author":"Dedoncker","year":"2016","journal-title":"Brain Stimul."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/cercor\/bhx347","article-title":"Effects of anodal transcranial direct current stimulation over the ventrolateral prefrontal cortex on episodic memory formation and retrieval","volume":"29","author":"Medvedeva","year":"2019","journal-title":"Cereb. Cortex"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.neuropsychologia.2015.06.021","article-title":"Reprint of: Transcranial direct current stimulation (tDCS)\u2013 Application in neuropsychology","volume":"74","author":"Shin","year":"2015","journal-title":"Neuropsychologia"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1016\/j.neurobiolaging.2015.04.016","article-title":"Effects of noninvasive brain stimulation on cognitive function in healthy aging and Alzheimer\u2019s disease: A systematic review and meta-analysis","volume":"36","author":"Hsu","year":"2015","journal-title":"Neurobiol. Aging"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3389\/fnagi.2013.00049","article-title":"Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation","volume":"5","author":"Manenti","year":"2013","journal-title":"Front. Aging Neurosci."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1016\/j.neurobiolaging.2011.05.007","article-title":"Non-invasive brain stimulation improves object-location learning in the elderly","volume":"33","author":"Suttorp","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.neurobiolaging.2015.12.010","article-title":"Older adults get episodic memory boosting from noninvasive stimulation of prefrontal cortex during learning","volume":"39","author":"Sandrini","year":"2016","journal-title":"Neurobiol. Aging"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3389\/fnagi.2014.00289","article-title":"Noninvasive stimulation of prefrontal cortex strengthens existing episodic memories and reduces forgetting in the elderly","volume":"6","author":"Sandrini","year":"2014","journal-title":"Front. Aging Neurosci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.brs.2011.08.003","article-title":"Short duration transcranial direct current stimulation (tDCS) modulates verbal memory","volume":"5","author":"Javadi","year":"2012","journal-title":"Brain Stimul."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"107037","DOI":"10.1016\/j.nlm.2019.107037","article-title":"Transcranial direct current stimulation applied after encoding facilitates episodic memory consolidation in older adults","volume":"163","author":"Sandrini","year":"2019","journal-title":"Neurobiol. Learn Mem."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"8883046","DOI":"10.1155\/2020\/8883046","article-title":"Transcranial direct current stimulation enhances episodic memory in healthy older adults by modulating retrieval-specific activation","volume":"2020","author":"Huo","year":"2020","journal-title":"Neural. Plast."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.neuroimage.2013.07.083","article-title":"Battery powered thought: Enhancement of attention, learning, and memory in healthy adults using transcranial direct current stimulation","volume":"85","author":"Coffman","year":"2014","journal-title":"Neuroimage"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0028-3932(03)00124-6","article-title":"Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human","volume":"42","author":"Kincses","year":"2004","journal-title":"Neuropsychologia"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neuroimage.2015.05.019","article-title":"Focalised stimulation using high definition transcranial direct current stimulation (HD-tDCS) to investigate declarative verbal learning and memory functioning","volume":"117","author":"Nikolin","year":"2015","journal-title":"Neuroimage"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1162\/jocn_a_00657","article-title":"Transcranial direct current stimulation enhances verbal working memory training performance over time and near transfer outcomes","volume":"26","author":"Richmond","year":"2014","journal-title":"J. Cogn. Neurosci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s00221-005-2334-6","article-title":"Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory","volume":"166","author":"Fregni","year":"2005","journal-title":"Exp. Brain Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.brs.2018.01.003","article-title":"Effects of tDCS dosage on working memory in healthy participants","volume":"11","author":"Nikolin","year":"2018","journal-title":"Brain Stimul."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.brs.2015.10.006","article-title":"Effects of anodal transcranial direct current stimulation on working memory: A systematic review and meta-analysis of findings from healthy and neuropsychiatric populations","volume":"9","author":"Hill","year":"2016","journal-title":"Brain Stimul."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.neuropsychologia.2018.04.022","article-title":"Effects of prefrontal tDCS on executive function: Methodological considerations revealed by meta-analysis","volume":"117","author":"Imburgio","year":"2018","journal-title":"Neuropsychologia"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.brs.2018.11.008","article-title":"A systematic review and meta-analysis of the effects of transcranial direct current stimulation (tDCS) on episodic memory","volume":"12","author":"Galli","year":"2019","journal-title":"Brain Stimul."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini Mental State. A practical method for grading the cognitive state of patients for the clinical","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatry Res."},{"key":"ref_29","unstructured":"Benedet, M.J., and Alejandre, M.\u00c1. (1998). TAVEC: Test de Aprendizaje Verbal Espa\u00f1a-Complutense, TEA Ediciones."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1037\/0012-1649.25.2.247","article-title":"Testing-the-limits and the study of adult age differences in cognitive plasticity of a mnemonic skill","volume":"25","author":"Kliegl","year":"1989","journal-title":"Dev. Psychol."},{"key":"ref_31","unstructured":"Wechsler, D. (2001). Wechsler Intelligence Scale for Adults-III (WAIS-III), TEA Ediciones."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.neuroscience.2017.10.042","article-title":"Interaction of the left dorsolateral prefrontal cortex (l-DLPFC) and right orbitofrontal cortex (OFC) in hot and cold executive functions: Evidence from transcranial direct current stimulation (tDCS)","volume":"369","author":"Nejati","year":"2018","journal-title":"Neuroscience"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Goldstein, S., and Naglieri, J.A. (2014). The frontal lobes and executive functioning. Handbook of Executive Functioning, Springer.","DOI":"10.1007\/978-1-4614-8106-5"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1136\/jnnp.2007.141853","article-title":"Temporal cortex direct current stimulation enhances performance on a visual recognition memory task in Alzheimer disease","volume":"80","author":"Boggio","year":"2009","journal-title":"J. Neurol. Neurosurg. Psychiatr."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1007\/s10072-019-03903-6","article-title":"Effects on cognition of 20-day anodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex in patients affected by mild cognitive impairment: A case-control study","volume":"40","author":"Fileccia","year":"2019","journal-title":"Neurol. Sci."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"12477","DOI":"10.1038\/s41598-018-30127-z","article-title":"Cognitive effects of transcranial direct current stimulation combined with working memory training in fibromyalgia: A randomized clinical trial","volume":"8","author":"Santos","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/cns.12779","article-title":"No effect of transcranial direct current stimulation of the dorsolateral prefrontal cortex on short-term memory","volume":"24","author":"Wang","year":"2018","journal-title":"CNS Neurosci. Ther."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.brs.2012.12.005","article-title":"The role of timing in the induction of neuromodulation in perceptual learning by transcranial electric stimulation","volume":"6","author":"Pirulli","year":"2013","journal-title":"Brain Stimul."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"101065","DOI":"10.1016\/j.arr.2020.101065","article-title":"Effects of transcranial electrical stimulation on episodic memory in physiological and pathological ageing","volume":"61","author":"Sandrini","year":"2020","journal-title":"Ageing Res. Rev."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Mel\u00e9ndez, J.C., Satorres, E., Pitarque, A., Delhom, I., Real, E., and Escudero, J. (2021). Effectiveness of tDCS at improving recognition and reducing false memories in older adults. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18031317"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1073\/pnas.1221572110","article-title":"Using model-based functional MRI to locate working memory updates and declarative memory retrievals in the fronto-parietal network","volume":"110","author":"Borst","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3389\/fnins.2017.00452","article-title":"Anodal tDCS over the left DLPFC did not affect the encoding and retrieval of verbal declarative information","volume":"11","author":"Lara","year":"2017","journal-title":"Front. Neurosci."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Pisoni, A., Turi, Z., Raithel, A., Ambrus, G.G., Alekseichuk, I., Schacht, A., Paulus, W., and Antal, A. (2015). Separating recognition processes of declarative memory via anodal tDCS: Boosting old item recognition by temporal and new item detection by parietal stimulation. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0123085"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.conb.2015.07.009","article-title":"Memory engram storage and retrieval","volume":"35","author":"Tonegawa","year":"2015","journal-title":"Curr. Res. Neurobiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"104788","DOI":"10.1016\/j.bandl.2020.104788","article-title":"Multisession transcranial direct current stimulation facilitates verbal learning and memory consolidation in young and older adults","volume":"205","author":"Perceval","year":"2020","journal-title":"Brain Lang."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/j.brs.2020.09.004","article-title":"Age-related differences of motor cortex plasticity in adults: A transcranial direct current stimulation study","volume":"13","author":"Farnad","year":"2020","journal-title":"Brain Stimul."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3389\/fnagi.2014.00131","article-title":"The timing of cognitive plasticity in physiological aging: A tDCS study of naming","volume":"6","author":"Fertonani","year":"2014","journal-title":"Front. Aging Neurosci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1002\/hbm.21104","article-title":"Modulating functional connectivity patterns and topological functional organization of the human brain with transcranial direct current stimulation","volume":"32","author":"Nitsche","year":"2011","journal-title":"Hum. Brain Mapp."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.brs.2011.08.006","article-title":"Modulation of large-scale brain networks by transcranial direct current stimulation evidenced by resting-state functional MRI","volume":"5","author":"Clemente","year":"2012","journal-title":"Brain Stimul."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neures.2018.12.007","article-title":"Improving working memory and pain inhibition in older persons using transcranial direct current stimulation","volume":"148","author":"Deldar","year":"2019","journal-title":"Neurosci. Res."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Jones, K.T., Stephens, J.A., Alam, M., Bikson, M., and Berryhill, M.E. (2015). Longitudinal neurostimulation in older adults improves working memory. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0129751"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3389\/fnagi.2019.00340","article-title":"Effects of transcranial direct current stimulation paired with cognitive training on functional connectivity of the working memory network in older adults","volume":"11","author":"Nissim","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.brs.2019.04.008","article-title":"Combining electrical stimulation and cognitive control training to reduce concerns about subjective cognitive decline","volume":"12","author":"Stoynova","year":"2019","journal-title":"Brain Stimul."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bandc.2014.01.008","article-title":"Working memory improvement with noninvasive brain stimulation of the dorsolateral prefrontal cortex: A systematic review and meta-analysis","volume":"86","author":"Brunoni","year":"2014","journal-title":"Brain Cogn."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1162\/jocn_a_00956","article-title":"Does transcranial direct current stimulation improve healthy working memory? A meta-analytic review","volume":"28","author":"Mancuso","year":"2016","journal-title":"J. Cogn. Neurosci."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/s00259-003-1382-z","article-title":"The prefrontal cortex: Insights from functional neuroimaging using cognitive activation tasks","volume":"31","author":"Goethals","year":"2004","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1152\/jn.00041.2021","article-title":"Neural substrate and underlying mechanisms of working memory: Insights from brain stimulation studies","volume":"125","author":"Haque","year":"2021","journal-title":"J. Neurophysiol."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/19\/12716\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:46:37Z","timestamp":1760143597000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/19\/12716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,5]]},"references-count":57,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["ijerph191912716"],"URL":"https:\/\/doi.org\/10.3390\/ijerph191912716","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,5]]}}}