{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:53:03Z","timestamp":1791841983684,"version":"4.3.4"},"reference-count":34,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T00:00:00Z","timestamp":1666224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Infertility is a problem that affects millions of couples worldwide and has a significant impact on their quality of life. The recently introduced \u201cFertility Quality of Life Questionnaire (FertiQoL)\u201d quickly became a gold standard for evaluation of the quality of life of patients suffering from infertility. The aim of this study was to determine the quality of life of Kazakhstani women coping with infertility problems by FertiQoL and assess the validity of the questionnaire. This cross-sectional study involved women of reproductive age undergoing an in vitro fertilization (IVF) cycle at a large IVF center in Kazakhstan in the period from 1 September 2020 to 31 September 2021. A total of 453 women out of 500 agreed to participate in the study, and the response rate was 90.6%. The overall Core FertiQoL was 56.95 \u00b1 14.05, and the Treatment FertiQoL was 66.18 \u00b1 11.13 points. Respondents with secondary infertility had statistically significantly higher Emotional (p &lt; 0.001), Mind\u2013body (p = 0.03), Social (p &lt; 0.001), Environment (p = 0.02), and Treatment (p &lt; 0.001) domains of FertiQoL than women with primary infertility. Respondents with a low income had the lowest levels of Total FertiQoL (56.72 \u00b1 11.65). The longer duration of infertility of women undergoing IVF treatment presented the worse scale of Treatment and Total FertiQoL. Cronbach\u2019s alpha revealed good internal reliability for all FertiQoL subscales on the Kazakhstan women\u2019s questionnaire and averaged 0.8, which is an indicator of a high degree of reliability. The Total FertiQoL of Kazakhstan women undergoing IVF treatment was 59.6 \u00b1 11.5, which is considerably lower than European countries. We identified statistically significant differences across medical and demographic groups. As this questionnaire had validity in Kazakhstan survey it possibly be used for both medical counseling and future investigation in our country.<\/jats:p>","DOI":"10.3390\/ijerph192013568","type":"journal-article","created":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T22:19:53Z","timestamp":1666217993000},"page":"13568","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Quality-of-Life Assessment of Women Undergoing In Vitro Fertilization in Kazakhstan"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4861-7953","authenticated-orcid":false,"given":"Meruyert","family":"Suleimenova","sequence":"first","affiliation":[{"name":"Department of Public Health and Social Sciences, Kazakhstan Medical University \u201cKSPH\u201d, Almaty 050000, Kazakhstan"},{"name":"Department of Assisted Reproductive Technologies, International Clinical Centre of Reproduction \u201cPERSONA\u201d, Almaty 050000, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4792-5380","authenticated-orcid":false,"given":"Vyacheslav","family":"Lokshin","sequence":"additional","affiliation":[{"name":"Department of Assisted Reproductive Technologies, International Clinical Centre of Reproduction \u201cPERSONA\u201d, Almaty 050000, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1400-8436","authenticated-orcid":false,"given":"Natalya","family":"Glushkova","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Biostatistics and Evidence Based Medicine, Al-Farabi Kazakh National University, Almaty 050000, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sholpan","family":"Karibayeva","sequence":"additional","affiliation":[{"name":"Department of Assisted Reproductive Technologies, International Clinical Centre of Reproduction \u201cPERSONA\u201d, Almaty 050000, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3914-5154","authenticated-orcid":false,"given":"Milan","family":"Terzic","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Medicine, Nazarbayev University, Nur-Sultan 010000, Kazakhstan"},{"name":"Clinical Academic Department of Women\u2019s Health, Corporate Fund \u201cUniversity Medical Center\u201d, Nur-Sultan 010000, Kazakhstan"},{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Practice Committee of the American Society for Reproductive Medicine (2020). 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