{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:49:40Z","timestamp":1790455780656,"version":"4.1.0"},"reference-count":56,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000066","name":"U.S. National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R01ES010178"],"award-info":[{"award-number":["R01ES010178"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Women and children in rural regions of low-income countries are exposed to high levels of household air pollution (HAP) as they traditionally tend to household chores such as cooking with biomass fuels. Early life exposure to air pollution is associated with aeroallergen sensitization and developing allergic diseases at older ages. This prospective cohort study assigned HAP-reducing chimney stoves to 557 households in rural Guatemala at different ages of the study children. The children\u2019s air pollution exposure was measured using personal CO diffusion tubes. Allergic outcomes at 4\u20135 years old were assessed using skin prick tests and International Study of Asthma and Allergies in Childhood (ISAAC)-based questionnaires. Children assigned to improved stoves before 6 months old had the lowest HAP exposure compared to the other groups. Longer exposure to the unimproved stoves was associated with higher risks of maternal-reported allergic asthma (OR = 2.42, 95% CI: 1.11\u20135.48) and rhinitis symptoms (OR = 2.01, 95% CI: 1.13\u20133.58). No significant association was found for sensitization to common allergens such as dust mites and cockroaches based on skin prick tests. Reducing HAP by improving biomass burning conditions might be beneficial in preventing allergic diseases among children in rural low-income populations.<\/jats:p>","DOI":"10.3390\/ijerph192114064","type":"journal-article","created":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T04:57:34Z","timestamp":1667105854000},"page":"14064","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Biomass Smoke Exposure and Atopy among Young Children in the Western Highlands of Guatemala: A Prospective Cohort Study"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3861-9143","authenticated-orcid":false,"given":"Wenxin","family":"Lu","sequence":"first","affiliation":[{"name":"School of Public Health, University of California, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Ann","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Colorado, Aurora, CO 80045, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Mann","sequence":"additional","affiliation":[{"name":"School of Public Health, University of California, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alisa","family":"Jenny","sequence":"additional","affiliation":[{"name":"Institute for Global Health Sciences, University of California, San Francisco, CA 94158, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Romero","sequence":"additional","affiliation":[{"name":"Centro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City 01015, Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Kuster","sequence":"additional","affiliation":[{"name":"School of Nursing, University of California, San Francisco, CA 94158, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Canuz","sequence":"additional","affiliation":[{"name":"Centro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City 01015, Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Pillarisetti","sequence":"additional","affiliation":[{"name":"School of Public Health, University of California, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirk R.","family":"Smith","sequence":"additional","affiliation":[{"name":"School of Public Health, University of California, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2246-7002","authenticated-orcid":false,"given":"John","family":"Balmes","sequence":"additional","affiliation":[{"name":"School of Public Health, University of California, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8001-2057","authenticated-orcid":false,"given":"Lisa","family":"Thompson","sequence":"additional","affiliation":[{"name":"Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,28]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (WHO) (2022, July 28). 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