{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T07:49:01Z","timestamp":1785311341036,"version":"3.55.0"},"reference-count":60,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:00:00Z","timestamp":1667433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Robert Koch Institute, Germany","award":["LongCOV_521"],"award-info":[{"award-number":["LongCOV_521"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Post-COVID conditions in children and adolescents were mostly investigated as the incidence of individual or clusters of symptoms. We aimed to describe the findings of studies assessing key outcomes related to global wellbeing and recovery in children and adolescents from a public health perspective. We searched the Cochrane COVID-19 Study Register and WHO COVID-19 Global literature on coronavirus disease database on 5 November 2021 and tracked ongoing studies published after this date. We included observational studies on children and adolescents with a follow-up greater than 12 weeks and focused on the outcomes of quality of life, recovery\/duration of symptoms, school attendance and resource use\/rehabilitation. We assessed their methodological quality, and we prepared a narrative synthesis of the results. We included 21 longitudinal and 4 cross-sectional studies (6 with a control group) with over 68 thousand unvaccinated children and adolescents with mostly asymptomatic or mild disease. Study limitations included convenience sampling, a poor description of their study population and heterogeneous definitions of outcomes. Quality of life was not largely affected in adolescents following COVID-19, but there might be greater impairment in young children and in those with more severe forms of the disease (4 studies). There might also be an impairment in daily activities and increased school absenteeism following COVID-19, but the findings were heterogeneous (5 studies). A total of 22 studies provided highly variable estimates based on heterogeneous definitions of overall persistence of symptoms (recovery), ranging from 0 to 67% at 8\u201312 weeks and 8 to 51% at 6\u201312 months. We found limited data on resource use and the need for rehabilitation. One controlled study indicated that the quality of life of infected children and adolescents might not substantially differ from controls. All controlled studies found a higher burden of persistent symptoms in COVID-19 cases compared with test-negative controls or cases of influenza. There is limited evidence on the short and long-term well-being of children following SARS-CoV-2 infection. High-quality longitudinal studies with control groups are needed to describe the outcomes in this population, especially in vaccinated children and those affected by new variants of the virus.<\/jats:p>","DOI":"10.3390\/ijerph192114392","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T03:28:10Z","timestamp":1667532490000},"page":"14392","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Short and Long-Term Wellbeing of Children following SARS-CoV-2 Infection: A Systematic Review"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0411-899X","authenticated-orcid":false,"given":"Juan Victor Ariel","family":"Franco","sequence":"first","affiliation":[{"name":"Institute of General Practice, Medical Faculty, Heinrich-Heine-University D\u00fcsseldorf, 40225 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Ignacio","family":"Garegnani","sequence":"additional","affiliation":[{"name":"Research Department, Instituto Universitario Hospital Italiano de Buenos Aires, Buenos Aires 4234, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisela Viviana","family":"Oltra","sequence":"additional","affiliation":[{"name":"Research Department, Instituto Universitario Hospital Italiano de Buenos Aires, Buenos Aires 4234, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4154-5782","authenticated-orcid":false,"given":"Maria-Inti","family":"Metzendorf","sequence":"additional","affiliation":[{"name":"Institute of General Practice, Medical Faculty, Heinrich-Heine-University D\u00fcsseldorf, 40225 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7983-4870","authenticated-orcid":false,"given":"Leonel Fabrizio","family":"Trivisonno","sequence":"additional","affiliation":[{"name":"Department of Health Science, Universidad Nacional de La Matanza, Buenos Aires 1754, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Sgarbossa","sequence":"additional","affiliation":[{"name":"Department of Health Science, Universidad Nacional de La Matanza, Buenos Aires 1754, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Ducks","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Monitoring, Robert Koch-Institute, 13353 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Heldt","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Monitoring, Robert Koch-Institute, 13353 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebekka","family":"Mumm","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Monitoring, Robert Koch-Institute, 13353 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2264-2042","authenticated-orcid":false,"given":"Benjamin","family":"Barnes","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Monitoring, Robert Koch-Institute, 13353 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christa","family":"Scheidt-Nave","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Monitoring, Robert Koch-Institute, 13353 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1007\/s43440-020-00204-0","article-title":"SARS-CoV-2 therapeutics: How far do we stand from a remedy?","volume":"73","author":"Singh","year":"2021","journal-title":"Pharmacol. Rep."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1001\/jama.2020.12839","article-title":"Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review","volume":"324","author":"Wiersinga","year":"2020","journal-title":"JAMA"},{"key":"ref_3","unstructured":"(2022, May 17). Child Mortality and COVID-19. UNICEF DATA. Available online: https:\/\/data.unicef.org\/topic\/child-survival\/covid-19\/."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"113426","DOI":"10.1016\/j.socscimed.2020.113426","article-title":"How and why patients made Long Covid","volume":"268","author":"Callard","year":"2020","journal-title":"Soc. Sci. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"m3489","DOI":"10.1136\/bmj.m3489","article-title":"Long covid: How to define it and how to manage it","volume":"370","author":"Nabavi","year":"2020","journal-title":"BMJ"},{"key":"ref_6","unstructured":"World Health Organization (WHO) Clinical Case Definition Working Group on Post COVID-19 Condition (2021, October 22). A Clinical Case Definition of Post COVID-19 Condition by a Delphi Consensus, 6 October 2021. Available online: https:\/\/www.who.int\/publications\/i\/item\/WHO-2019-nCoV-Post_COVID-19_condition-Clinical_case_definition-2021.1."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1136\/archdischild-2021-323624","article-title":"Long COVID (post-COVID-19 condition) in children: A modified Delphi process","volume":"107","author":"Stephenson","year":"2022","journal-title":"Arch. Dis. Child."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e005427","DOI":"10.1136\/bmjgh-2021-005427","article-title":"Characterising long COVID: A living systematic review","volume":"6","author":"Michelen","year":"2021","journal-title":"BMJ Glob. Health"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"16144","DOI":"10.1038\/s41598-021-95565-8","article-title":"More than 50 long-term effects of COVID-19: A systematic review and meta-analysis","volume":"11","author":"Perelman","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_10","first-page":"e14357","article-title":"Frequency, signs and symptoms, and criteria adopted for long COVID-19: A systematic review","volume":"75","author":"Martimbianco","year":"2021","journal-title":"Int. J. Clin. Pract."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e2128568","DOI":"10.1001\/jamanetworkopen.2021.28568","article-title":"Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection","volume":"4","author":"Groff","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3331","DOI":"10.1111\/apa.16071","article-title":"Clinical characteristics of paediatric COVID-19 patients followed for up to 13 months","volume":"110","author":"Matteudi","year":"2021","journal-title":"Acta Paediatr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/00016489.2020.1855366","article-title":"Smell and taste loss in COVID-19 patients: Assessment outcomes in a Victorian population","volume":"141","author":"Horvath","year":"2021","journal-title":"Acta Otolaryngol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1017\/S1047951121003693","article-title":"Intriguing new faces of Covid-19: Persisting clinical symptoms and cardiac effects in children","volume":"32","author":"Erol","year":"2021","journal-title":"Cardiol. Young"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e482","DOI":"10.1097\/INF.0000000000003328","article-title":"How Common is Long COVID in Children and Adolescents?","volume":"40","author":"Zimmermann","year":"2021","journal-title":"Pediatr. Infect. Dis. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"9950","DOI":"10.1038\/s41598-022-13495-5","article-title":"Long-COVID in children and adolescents: A systematic review and meta-analyses","volume":"12","author":"Perelman","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jinf.2021.11.011","article-title":"Persistent symptoms following SARS-CoV-2 infection amongst children and young people: A meta-analysis of controlled and uncontrolled studies","volume":"84","author":"Behnood","year":"2021","journal-title":"J. Infect."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Franco, J.V.A., Garegnani, L.I., Oltra, G.V., Metzendorf, M.-I., Trivisonno, L.F., Sgarbossa, N., Ducks, D., Heldt, K., Mumm, R., and Barnes, B. (2022). Long-Term Health Symptoms and Sequelae Following SARS-CoV-2 Infection: An Evidence Map. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19169915"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/XEB.0000000000000054","article-title":"Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and cumulative incidence data","volume":"13","author":"Munn","year":"2015","journal-title":"Int. J. Evid.-Based Healthc."},{"key":"ref_20","unstructured":"Franco, J.V.A., Oltra, G., Metzendorf, M.-I., Garegnani, L.I., Ducks, D., Heldt, K., Mumm, R., Barnes, B., and Scheidt-Nave, C. (2021). LongCOV_521, RKI."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"l6890","DOI":"10.1136\/bmj.l6890","article-title":"Synthesis without meta-analysis (SWiM) in systematic reviews: Reporting guideline","volume":"368","author":"Campbell","year":"2020","journal-title":"BMJ"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1038\/s41591-021-01433-3","article-title":"Long COVID in a prospective cohort of home-isolated patients","volume":"27","author":"Blomberg","year":"2021","journal-title":"Nat. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"621019","DOI":"10.3389\/fped.2021.621019","article-title":"Can Asymptomatic or Non-Severe SARS-CoV-2 Infection Cause Medium-Term Pulmonary Sequelae in Children?","volume":"9","author":"Bottino","year":"2021","journal-title":"Front. Pediatr."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1111\/apa.15870","article-title":"Preliminary evidence on long COVID in children","volume":"110","author":"Buonsenso","year":"2021","journal-title":"Acta Paediatr."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s43168-020-00049-4","article-title":"Determinants of persistent post-COVID-19 symptoms: Value of a novel COVID-19 symptom score","volume":"15","author":"Galal","year":"2021","journal-title":"Egypt. J. Bronc."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"110823","DOI":"10.1016\/j.ijporl.2021.110823","article-title":"Dysphonia and dysphagia consequences of paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS)","volume":"148","author":"Halfpenny","year":"2021","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1002\/jmv.26871","article-title":"The comprehensive clinic, laboratory, and instrumental evaluation of children with COVID-19: A 6-months prospective study","volume":"93","author":"Isoldi","year":"2021","journal-title":"J. Med. Virol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S2352-4642(22)00004-9","article-title":"Long COVID symptoms in SARS-CoV-2-positive adolescents and matched controls (LongCOVIDKidsDK): A national, cross-sectional study","volume":"6","author":"Berg","year":"2022","journal-title":"Lancet Child Adolesc. Health"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S2352-4642(22)00154-7","article-title":"Long COVID symptoms in SARS-CoV-2-positive children aged 0\u201314 years and matched controls in Denmark (LongCOVIDKidsDK): A national, cross-sectional study","volume":"6","author":"Berg","year":"2022","journal-title":"Lancet Child Adolesc. Health"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"617689","DOI":"10.3389\/fmed.2021.617689","article-title":"Health Issues and Immunological Assessment Related to Wuhan\u2019s COVID-19 Survivors: A Multicenter Follow-Up Study","volume":"8","author":"Mei","year":"2021","journal-title":"Front. Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"663670","DOI":"10.3389\/fmed.2021.663670","article-title":"Clinical Characteristics and the Long-Term Post-recovery Manifestations of the COVID-19 Patients\u2014A Prospective Multicenter Cross-Sectional Study","volume":"8","author":"Chowdhury","year":"2021","journal-title":"Front. Med."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.cmi.2020.12.021","article-title":"Long-term persistence of olfactory and gustatory disorders in COVID-19 patients","volume":"27","author":"Nguyen","year":"2021","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2101341","DOI":"10.1183\/13993003.01341-2021","article-title":"Risk factors for post-COVID-19 condition in previously hospitalised children using the ISARIC Global follow-up protocol: A prospective cohort study","volume":"59","author":"Osmanov","year":"2021","journal-title":"Eur. Respir. J."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1007\/s00296-021-04932-1","article-title":"Short-term outcomes in children recovered from multisystem inflammatory syndrome associated with SARS-CoV-2 infection","volume":"41","author":"Patnaik","year":"2021","journal-title":"Rheumatol. Int."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S2352-4642(21)00138-3","article-title":"6-month multidisciplinary follow-up and outcomes of patients with paediatric inflammatory multisystem syndrome (PIMS-TS) at a UK tertiary paediatric hospital: A retrospective cohort study","volume":"5","author":"Penner","year":"2021","journal-title":"Lancet Child Adolesc. Health"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"e4058","DOI":"10.1093\/cid\/ciaa1792","article-title":"Long COVID in the Faroe Islands: A Longitudinal Study Among Nonhospitalized Patients","volume":"73","author":"Petersen","year":"2020","journal-title":"Clin. Infect. Dis."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1111\/jocn.15733","article-title":"Health-related quality of life of COVID-19 patients after discharge: A multicenter follow-up study","volume":"30","author":"Qu","year":"2021","journal-title":"J. Clin. Nurs."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1001\/jama.2021.11880","article-title":"Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents","volume":"326","author":"Radtke","year":"2021","journal-title":"JAMA"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Budhiraja, S., Aggarwal, M., Wig, R., Tyagi, A., Mishra, R.S., Mahajan, M., Kirtani, J., Tickoo, R., Bali, S., and Dewan, A. (2021). Long Term Health Consequences of COVID-19 in Hospitalized Patients from North India: A follow up study of upto 12 months. bioRxiv.","DOI":"10.1101\/2021.06.21.21258543"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Roessler, M., Tesch, F., Batram, M., Jacob, J., Loser, F., Weidinger, O., Wende, D., Vivirito, A., Toepfner, N., and Seifert, M. (2021). Post COVID-19 in children, adolescents, and adults: Results of a matched cohort study including more than 150,000 individuals with COVID-19. bioRxiv.","DOI":"10.1101\/2021.10.21.21265133"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1016\/S2352-4642(21)00124-3","article-title":"Post-acute COVID-19 outcomes in children with mild and asymptomatic disease","volume":"5","author":"Say","year":"2021","journal-title":"Lancet Child Adolesc. Health"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1186\/s13052-021-01127-z","article-title":"Clinical features of pediatric post-acute COVID-19: A descriptive retrospective follow-up study","volume":"47","author":"Smane","year":"2021","journal-title":"Ital. J. Pediatr."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S2352-4642(22)00022-0","article-title":"Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England (CLoCk): A national matched cohort study","volume":"6","author":"Stephenson","year":"2022","journal-title":"Lancet Child Adolesc. Health"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Taquet, M., Dercon, Q., Luciano, S., Geddes, J.R., Husain, M., and Harrison, P.J. (2021). Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19. PLoS Med., 18.","DOI":"10.1371\/journal.pmed.1003773"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Walsh-Messinger, J., Manis, H., Vrabec, A., Sizemore, B.J., Bishof, K., Debidda, M., Malaspina, D., and Greenspan, N. (2021). The kids are not alright: A preliminary report of Post-COVID syndrome in university students. J. Am. Coll. Health, 1\u20137.","DOI":"10.1101\/2020.11.24.20238261"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"fcaa205","DOI":"10.1093\/braincomms\/fcaa205","article-title":"Frequent neurocognitive deficits after recovery from mild COVID-19","volume":"2","author":"Woo","year":"2020","journal-title":"Brain Commun."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e14260","DOI":"10.1111\/ijcp.14260","article-title":"Clinical, sinonasal, and long-term smell and taste outcomes in mildly symptomatic COVID-19 patients","volume":"75","author":"Tarifi","year":"2021","journal-title":"Int. J. Clin. Pract."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Pazukhina, E., Andreeva, M., Spiridonova, E., Bobkova, P., Shikhaleva, A., El-Taravi, Y., Rumyantsev, M., Gamirova, A., Bairashevskaia, A., and Petrova, P. (2022). Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: A prospective, cohort study in Moscow (StopCOVID). BMC Med., 20.","DOI":"10.2139\/ssrn.4020142"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e042121","DOI":"10.1136\/bmjopen-2020-042121","article-title":"Prospective cohort study of children with suspected SARS-CoV-2 infection presenting to paediatric emergency departments: A Paediatric Emergency Research Networks (PERN) Study Protocol","volume":"11","author":"Funk","year":"2021","journal-title":"BMJ Open"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e2142322","DOI":"10.1001\/jamanetworkopen.2021.42322","article-title":"Outcomes of SARS-CoV-2\u2013Positive Youths Tested in Emergency Departments","volume":"5","author":"Funk","year":"2022","journal-title":"JAMA Netw. Open"},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Hirt, J., Janiaud, P., Gloy, V.L., Schandelmaier, S., Pereira, T.V., Contopoulos-Ioannidis, D., Goodman, S.N., Ioannidis, J., Munkholm, K., and Hemkens, L.G. (2022). Robustness of reported postacute health outcomes in children with SARS-CoV-2 infection: A systematic review. Arch. Dis. Child., online.","DOI":"10.1101\/2022.03.18.22272582"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Pellegrino, R., Chiappini, E., Licari, A., Galli, L., and Marseglia, G.L. (2022). Prevalence and clinical presentation of long COVID in children: A systematic review. Eur. J. Pediatr., 1\u201315.","DOI":"10.1007\/s00431-022-04600-x"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e066809","DOI":"10.1136\/bmj-2021-066809","article-title":"Healthcare use in 700,000 children and adolescents for six months after covid-19: Before and after register based cohort study","volume":"376","author":"Magnusson","year":"2022","journal-title":"BMJ"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Paterson, C., Davis, D., Roche, M., Bissett, B., Roberts, C., Turner, M., Baldock, E., and Mitchell, I. (2022). What are the long-term holistic health consequences of COVID-19 among survivors? An umbrella systematic review. J. Med. Virol., online.","DOI":"10.1002\/jmv.28086"},{"key":"ref_56","unstructured":"Lelii, F., Ford, B., Stocker, D., and Toon, S. (2022, June 24). COVID-19 Schools Infection Survey, England\u2014Office for National Statistics, Available online: https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/healthandsocialcare\/conditionsanddiseases\/bulletins\/covid19schoolsinfectionsurveyengland\/march2022."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/S2213-2600(22)00211-9","article-title":"Post-COVID-19 condition in children: A COS is urgently needed","volume":"10","author":"Munblit","year":"2022","journal-title":"Lancet Respir. Med."},{"key":"ref_58","first-page":"CD014962","article-title":"Remdesivir for the treatment of COVID-19","volume":"8","author":"Ansems","year":"2021","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_59","first-page":"CD015025","article-title":"Antibiotics for the treatment of COVID-19","volume":"10","author":"Popp","year":"2021","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_60","first-page":"CD015045","article-title":"Colchicine for the treatment of COVID-19","volume":"10","author":"Mikolajewska","year":"2021","journal-title":"Cochrane Database Syst. Rev."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/21\/14392\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:09:54Z","timestamp":1760144994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/21\/14392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,3]]},"references-count":60,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["ijerph192114392"],"URL":"https:\/\/doi.org\/10.3390\/ijerph192114392","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,3]]}}}