{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:14:17Z","timestamp":1787613257827,"version":"build-2736575974"},"reference-count":85,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T00:00:00Z","timestamp":1668729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health (NIH)","doi-asserted-by":"publisher","award":["R01DA044207"],"award-info":[{"award-number":["R01DA044207"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Cannabis use is prevalent among adolescents and young adults in the US. Virtually all modes of cannabis consumption involve the oral cavity, and previous studies have linked cannabis use with poorer oral health. We sought to identify associations between cannabis use and various oral health outcomes and behaviors among individuals 12\u201325 years of age, and to discuss implications for orthodontists who largely interact with this age group over an extended period of treatment time. We examined data from patient electronic health records (N = 14,657) obtained between 2015 and 2021. Associations between lifetime and current self-reported cannabis use and several oral health outcomes or related behaviors that reflect periodontal health, caries status, oral lesions, and physical integrity of tooth structure and restorations were examined in a bivariable and multivariable manner, controlling for patient age, sex, and self-reported tobacco and alcohol use. Reporting lifetime cannabis use was associated with higher risk for having oral lesions (aPR = 1.41, 95% CI: 1.07\u20131.85), bruxism (aPR = 1.31, 95% CI: 1.09\u20131.58), and frequent consumption of sugary beverages and snacks (aPR = 1.27, 95% CI: 1.12\u20131.41). Reporting current cannabis use was associated with higher risk for oral lesions (aPR = 1.45, 95% CI: 1.03\u20132.06) and frequent consumption of sugary beverages and snacks (aPR = 1.26, 95% CI: 1.07\u20131.48). Cannabis users aged 12\u201325 are at increased risk for bruxism, oral lesions, and frequent consumption of sugary beverages and snacks. Orthodontists and other dental professionals should probe for drug use and be cognizant of increased risk for oral health problems in patients that report actively using cannabis.<\/jats:p>","DOI":"10.3390\/ijerph192215261","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T03:05:11Z","timestamp":1668999911000},"page":"15261","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Associations between Oral Health and Cannabis Use among Adolescents and Young Adults: Implications for Orthodontists"],"prefix":"10.3390","volume":"19","author":[{"given":"Austin","family":"Le","sequence":"first","affiliation":[{"name":"Department of Population Health, New York University Grossman School of Medicine, New York, NY 10016, USA"},{"name":"Department of Orthodontics and Dentofacial Orthopedics, New York University College of Dentistry, New York, NY 10010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmund","family":"Khoo","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Oral Facial Genetics, Indiana University School of Dentistry, Indianapolis, IN 46202, USA"},{"name":"Eastman Institute of Oral Health, University of Rochester, Rochester, NY 14620, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.","family":"Palamar","sequence":"additional","affiliation":[{"name":"Department of Population Health, New York University Grossman School of Medicine, New York, NY 10016, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/add.13670","article-title":"Demographic trends among older cannabis users in the United States, 2006\u20132013","volume":"112","author":"Han","year":"2016","journal-title":"Addiction"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1001\/jamainternmed.2019.7517","article-title":"Trends in Cannabis Use among Older Adults in the United States, 2015\u20132018","volume":"180","author":"Han","year":"2020","journal-title":"JAMA Intern. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1001\/jamapsychiatry.2017.0724","article-title":"US Adult Illicit Cannabis Use, Cannabis Use Disorder, and Medical Marijuana Laws: 1991\u20131992 to 2012\u20132013","volume":"74","author":"Hasin","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1001\/jamapsychiatry.2019.3254","article-title":"Association Between Recreational Marijuana Legalization in the United States and Changes in Marijuana Use and Cannabis Use Disorder from 2008 to 2016","volume":"77","author":"Cerda","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.drugalcdep.2011.06.011","article-title":"Medical marijuana laws in 50 states: Investigating the relationship between state legalization of medical marijuana and marijuana use, abuse and dependence","volume":"120","author":"Wall","year":"2012","journal-title":"Drug Alcohol Depend."},{"key":"ref_6","unstructured":"Ferr\u00e9-Sadurn\u00ed, L. (The New York Times, 2021). New York Legalizes Recreational Marijuana, Tying Move to Racial Equity, The New York Times."},{"key":"ref_7","unstructured":"National Conference of State Legislatures (2020). Marijuana Overview, National Conference of State Legislatures."},{"key":"ref_8","unstructured":"Caron, C. (The New York Times, 2022). Psychosis, Addiction, Chronic Vomiting: As Weed Becomes More Potent, Teens Are Getting Sick, The New York Times."},{"key":"ref_9","unstructured":"Jacobs, A. (The New York Times, 2022). Use of Marijuana and Psychedelics Is Soaring Among Young Adults, Study Finds, The New York Times."},{"key":"ref_10","unstructured":"Reinl, J. (Daily Mail, 2022). America\u2019s $30bn legalized cannabis industry is causing an \u2018explosion\u2019 of teen users: Candy-themed products sold with minimal oversight increase risk of addiction and psychosis among kids, experts warn, Daily Mail."},{"key":"ref_11","unstructured":"Fillmore, R. (2022, August 28). Adolescents Using Cannabis Are at Risk for Cannabis Hyperemesis. Available online: https:\/\/www.hopkinsallchildrens.org\/ACH-News\/General-News\/Adolescents-Using-Cannabis-Are-at-Risk-for-Cannabi."},{"key":"ref_12","unstructured":"Archie, A. (2022). Young Adults Are Using Marijuana and Hallucinogens at the Highest Rates on Record, NPR."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1176\/appi.ajp.2021.21010073","article-title":"Association of Cannabis Use\u2013Related Predictor Variables and Self-Reported Psychotic Disorders: U.S. Adults, 2001\u20132002 and 2012\u20132013","volume":"179","author":"Livne","year":"2022","journal-title":"Am. J. Psychiatry"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2174\/1874473711104040241","article-title":"Cannabinoid Hyperemesis Syndrome","volume":"4","author":"Sawaya","year":"2011","journal-title":"Curr. Drug Abus. Rev."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.amepre.2020.04.008","article-title":"Marijuana Legalization and Youth Marijuana, Alcohol, and Cigarette Use and Norms","volume":"59","author":"Bailey","year":"2020","journal-title":"Am. J. Prev. Med."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Miech, R.A., Johnston, L.D., O\u2019Malley, P.M., Bachman, J.G., Schulenberg, J.E., and Patrick, M.E. (2020). Monitoring the Future National Survey Results on Drug Use, 1975\u20132019: Volume I, Secondary School Students, Institute for Social Research, The University of Michigan.","DOI":"10.3998\/2027.42\/150622"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1080\/10826084.2017.1334069","article-title":"Adolescent Marijuana Use and Perceived Ease of Access Before and After Recreational Marijuana Implementation in Colorado","volume":"53","author":"Harpin","year":"2017","journal-title":"Subst. Use Misuse"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S2215-0366(22)00161-4","article-title":"Association of cannabis potency with mental ill health and addiction: A systematic review","volume":"9","author":"Petrilli","year":"2022","journal-title":"Lancet Psychiatry"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1111\/add.15253","article-title":"Changes in delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) concentrations in cannabis over time: Systematic review and meta-analysis","volume":"116","author":"Freeman","year":"2021","journal-title":"Addiction"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00406-019-00983-5","article-title":"New trends in cannabis potency in USA and Europe during the last decade (2008\u20132017)","volume":"269","author":"Chandra","year":"2019","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"ref_21","unstructured":"PRSC Cannabis Concentration Workgroup (2020). Cannabis Concentration and Health Risks: A Report for the Washington State Prevention Research Subcommittee (PRSC), Alcohol and Drug Abuse Institute."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"107900","DOI":"10.1016\/j.drugalcdep.2020.107900","article-title":"Modes of marijuana use\u2014Smoking, vaping, eating, and dabbing: Results from the 2016 BRFSS in 12 States","volume":"209","author":"Schauer","year":"2020","journal-title":"Drug Alcohol Depend."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.15288\/jsad.2019.80.46","article-title":"Modes of Marijuana Consumption Among Colorado High School Students Before and After the Initiation of Retail Marijuana Sales for Adults","volume":"80","author":"Tormohlen","year":"2019","journal-title":"J. Stud. Alcohol Drugs"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.amepre.2015.05.027","article-title":"Toking, Vaping, and Eating for Health or Fun: Marijuana Use Patterns in Adults, U.S., 2014","volume":"50","author":"Schauer","year":"2016","journal-title":"Am. J. Prev. Med."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1001\/jamapediatrics.2019.2627","article-title":"Changes in Prevalence of Marijuana Consumption Modes Among Colorado High School Students From 2015 to 2017","volume":"173","author":"Tormohlen","year":"2019","journal-title":"JAMA Pediatr."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.ajodo.2008.01.012","article-title":"Orthodontic dental patients and expenditures\u20142004","volume":"134","author":"Guay","year":"2008","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1067\/mod.2000.103775","article-title":"Orthodontic dental visits during 1987 and 1996","volume":"118","author":"Manski","year":"2000","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"489.e9","DOI":"10.1016\/j.ajodo.2007.08.016","article-title":"Socio-demographics of adult orthodontic visits in the United States","volume":"133","author":"Whitesides","year":"2008","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ajodo.2005.11.005","article-title":"Psychiatry in orthodontics. Part 2: Substance abuse among adolescents and its relevance to orthodontic practice","volume":"129","author":"Neeley","year":"2006","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1001\/jama.299.5.525","article-title":"Cannabis Smoking and Periodontal Disease Among Young Adults","volume":"299","author":"Thomson","year":"2008","journal-title":"JAMA"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/jre.12639","article-title":"Is the use of Cannabis associated with periodontitis? A systematic review and meta-analysis","volume":"54","author":"Chisini","year":"2019","journal-title":"J. Periodontal Res."},{"key":"ref_32","first-page":"493","article-title":"Cannabis Use and Oral Health in a National Cohort of Adults","volume":"49","author":"Chaffee","year":"2021","journal-title":"J. Calif. Dent. Assoc."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1001\/jamapsychiatry.2016.0637","article-title":"Associations Between Cannabis Use and Physical Health Problems in Early Midlife: A Longitudinal Compar-ison of Persistent Cannabis vs Tobacco Users","volume":"73","author":"Meier","year":"2016","journal-title":"JAMA Psychiatry"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1902\/jop.2016.160370","article-title":"Relationship Between Frequent Recreational Cannabis (Marijuana and Hashish) Use and Periodontitis in Adults in the United States: National Health and Nutrition Examination Survey 2011 to 2012","volume":"88","author":"Shariff","year":"2017","journal-title":"J. Periodontol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1834-7819.2005.tb00343.x","article-title":"General and oral health implications of cannabis use","volume":"50","author":"Cho","year":"2005","journal-title":"Aust. Dent. J."},{"key":"ref_36","first-page":"576","article-title":"Cannabis and caries--does regular cannabis use increase the risk of caries in cigarette smokers?","volume":"119","author":"Imfeld","year":"2009","journal-title":"Schweiz Mon. Zahnmed."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.jadohealth.2012.11.002","article-title":"The Effect of Tobacco and Marijuana Use on Dental Health Status in Nevada Adolescents: A Trend Analysis","volume":"52","author":"Ditmyer","year":"2013","journal-title":"J. Adolesc. Health"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1600-0528.1993.tb00725.x","article-title":"Effects of cannabis smoking on oral soft tissues","volume":"21","author":"Darling","year":"1993","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1600-0714.1990.tb00852.x","article-title":"Effect of cannabis use on oral candidal carriage","volume":"19","author":"Darling","year":"1990","journal-title":"J. Oral Pathol. Med."},{"key":"ref_40","first-page":"66","article-title":"Candidiasis of the tongue in cannabis users: A report of 2 cases","volume":"68","author":"Faustino","year":"2020","journal-title":"Gen. Dent."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/pde.14101","article-title":"Oral erosions associated with surreptitious marijuana vaping in an adolescent boy","volume":"37","author":"Ali","year":"2020","journal-title":"Pediatr. Dermatol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"S561","DOI":"10.4103\/jpbs.JPBS_576_20","article-title":"Oral sensations among individuals with illicit drug dependence in rehabilitation centers: A cross-sectional study","volume":"13","author":"Nishat","year":"2021","journal-title":"J. Pharm. Bioallied Sci."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Habib, G., Steinberg, D., and Jabbour, A. (2021). The impact of medical cannabis consumption on the oral flora and saliva. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0247044"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1111\/jgs.17719","article-title":"Cannabis use, comorbidities, and prescription medication use among older adults in a large healthcare system in Los Angeles, CA 2019\u20132020","volume":"70","author":"Javanbakht","year":"2022","journal-title":"J. Am. Geriatr. Soc."},{"key":"ref_45","unstructured":"Substance Abuse and Mental Health Services Administration (2021). Key Substance Use and Mental Health Indicators in the United States: Results from the 2020 National Survey on Drug Use and Health (HHS Publication No. PEP21-07-01-003, NSDUH Series H-56), Substance Abuse and Mental Health Services Administration."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e20171330","DOI":"10.1542\/peds.2017-1330","article-title":"Synthetic Cannabinoid Use among High School Seniors","volume":"140","author":"Palamar","year":"2017","journal-title":"Pediatrics"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1902\/jop.2012.110664","article-title":"Update of the Case Definitions for Population-Based Surveillance of Periodontitis","volume":"83","author":"Eke","year":"2012","journal-title":"J. Periodontol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/j.0022-0337.2001.65.10.tb03444.x","article-title":"Sugar Consumption and Caries Risk: A Systematic Review","volume":"65","author":"Burt","year":"2001","journal-title":"J. Dent. Educ."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.3945\/ajcn.114.089656","article-title":"Added sugars and periodontal disease in young adults: An analysis of NHANES III data","volume":"100","author":"Lula","year":"2014","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s00784-020-03387-1","article-title":"Higher sugar intake is associated with periodontal disease in adolescents","volume":"25","author":"Moreira","year":"2020","journal-title":"Clin. Oral Investig."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1590\/1807-3107bor-2017.vol31.0102","article-title":"Oral health assessment for users of marijuana and cocaine\/crack substances","volume":"31","author":"Sordi","year":"2017","journal-title":"Braz. Oral Res."},{"key":"ref_52","first-page":"36","article-title":"Significance of cannabis use to dental practice","volume":"77","author":"Maloney","year":"2011","journal-title":"N. Y. State Dent. J."},{"key":"ref_53","first-page":"k2","article-title":"Oral Health Implications of Cannabis Smoking: A Rapid Evidence Review","volume":"86","author":"Keboa","year":"2020","journal-title":"J. Can. Dent. Assoc."},{"key":"ref_54","first-page":"26","article-title":"Periodontal and oral manifestations of marijuana use","volume":"92","author":"Rawal","year":"2013","journal-title":"J. Tenn. Dent. Assoc."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1365-263X.2010.01078.x","article-title":"Oral mucosal lesions during orthodontic treatment","volume":"21","author":"Baricevic","year":"2010","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0889-5406(95)70073-0","article-title":"Oral lesions caused by an orthodontic retainer: A case report","volume":"108","author":"Bishara","year":"1995","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_57","unstructured":"James, L. (2022, March 03). Bruxism: The Grind of the Matter\u2014Treatment Modalities. Available online: https:\/\/www.dentalcare.com\/en-us\/professional-education\/ce-courses\/ce485\/treatment-modalities."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.jrp.2010.03.006","article-title":"Teeth grinding: Is Emotional Stability related to bruxism?","volume":"44","author":"Sutin","year":"2010","journal-title":"J. Res. Pers."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0022-3913(91)90240-W","article-title":"The social and psychologic factors of bruxism","volume":"65","author":"Pingitore","year":"1991","journal-title":"J. Prosthet. Dent."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"590779","DOI":"10.3389\/fneur.2020.590779","article-title":"Is There Association Between Stress and Bruxism? A Systematic Review and Meta-Analysis","volume":"11","author":"Chemelo","year":"2020","journal-title":"Front. Neurol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s42238-022-00135-y","article-title":"A description of self-medication with cannabis among adults with legal access to cannabis in Quebec, Canada","volume":"4","author":"Asselin","year":"2022","journal-title":"J. Cannabis Res."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.jsat.2008.08.005","article-title":"Stress-related factors in cannabis use and misuse: Implications for prevention and treatment","volume":"36","author":"Hyman","year":"2009","journal-title":"J. Subst. Abus. Treat."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Wallis, D., Coatsworth, J.D., Mennis, J., Riggs, N.R., Zaharakis, N., Russell, M.A., Brown, A.R., Rayburn, S., Radford, A., and Hale, C. (2022). Predicting Self-Medication with Cannabis in Young Adults with Hazardous Cannabis Use. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19031850"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"103621","DOI":"10.1016\/j.jdent.2021.103621","article-title":"The efficacy of occlusal splints in the treatment of bruxism: A systematic review","volume":"108","author":"Hardy","year":"2021","journal-title":"J. Dent."},{"key":"ref_65","unstructured":"Somers, J. (2022, January 10). ClearCorrect: Bruxism. Available online: https:\/\/support.clearcorrect.com\/hc\/en-us\/articles\/217800658-Bruxism."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/14659891.2018.1508518","article-title":"Oral health implications of increased cannabis use among older adults: Another public health concern?","volume":"24","author":"Le","year":"2019","journal-title":"J. Subst. Use"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1017\/S0954422414000080","article-title":"The endocannabinoid system and appetite: Relevance for food reward","volume":"27","author":"Jager","year":"2014","journal-title":"Nutr. Res. Rev."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jds.2011.09.002","article-title":"Effects of orthodontic treatment with a fixed appliance on the caries experience of patients with high and low risk of caries","volume":"6","author":"Karadas","year":"2011","journal-title":"J. Dent. Sci."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1111\/adj.12671","article-title":"Prevention and caries risk management in teenage and orthodontic patients","volume":"64","author":"Walsh","year":"2019","journal-title":"Aust. Dent. J."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"125","DOI":"10.4103\/2278-0203.143233","article-title":"Orthodontic bracket designs and their impact on microbial profile and periodontal disease: A clinical trial","volume":"3","author":"Moolya","year":"2014","journal-title":"J. Orthod. Sci."},{"key":"ref_71","unstructured":"Substance Abuse and Mental Health Services Administration (2020). Key Substance Use and Mental Health Indicators in the United States: Results from the 2019 National Survey on Drug Use and Health (HHS Publication No. PEP20-07-01-001, NSDUH Series H-55), Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration."},{"key":"ref_72","unstructured":"Le, A., and Palamar, J.J. (2022). Underreported drug use among dental patients: A call for dental professionals to improve drug use screening. J. Am. Dent. Assoc., S0002-8177(22)00569-4. (Advance online publication)."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1111\/add.13004","article-title":"Screening for substance misuse in the dental care setting: Findings from a nationally representative survey of dentists","volume":"110","author":"Parish","year":"2015","journal-title":"Addiction"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"627","DOI":"10.14219\/jada.archive.2013.0174","article-title":"Substance-use screening and interventions in dental practices: Survey of practice-based research network dentists regarding current practices, policies and barriers","volume":"144","author":"McNeely","year":"2013","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"136","DOI":"10.3389\/fendo.2012.00136","article-title":"Role of cannabinoids in the regulation of bone remodeling","volume":"3","author":"Idris","year":"2012","journal-title":"Front. Endocrinol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/00220345211036072","article-title":"Potential Mechanisms Underlying Marijuana-Associated Periodontal Tissue Destruction","volume":"101","author":"Scott","year":"2021","journal-title":"J. Dent. Res."},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Michelogiannakis, D., and Rahman, I. (2022). Influence of E-Cigarette and Cannabis Vaping on Orthodontically Induced Tooth Movement and Periodontal Health in Patients Undergoing Orthodontic Therapy. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19116518"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"e215","DOI":"10.1016\/j.ajodo.2021.07.012","article-title":"Dronabinol inhibits alveolar bone remodeling in tooth movement of rats","volume":"161","author":"Klein","year":"2022","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/ejo\/cjp165","article-title":"Root resorption before and after orthodontic treatment: A clinical study of contributory factors","volume":"32","author":"Jiang","year":"2010","journal-title":"Eur. J. Orthod."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/j.1834-7819.1997.tb00138.x","article-title":"Enamel demineralization during orthodontic treatment. Aetiology and prevention","volume":"42","author":"Chang","year":"1997","journal-title":"Aust. Dent. J."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/sj.bdj.2016.416","article-title":"Cannabis: A joint problem for patients and the dental profession","volume":"220","author":"Joshi","year":"2016","journal-title":"Br. Dent. J."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/ADM.0000000000000246","article-title":"Under-reporting of Risky Drug Use Among Primary Care Patients in Federally Qualified Health Centers","volume":"10","author":"Bone","year":"2016","journal-title":"J. Addict. Med."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s13011-021-00398-3","article-title":"Validity of self-reported substance use: Research setting versus primary health care setting","volume":"16","author":"Khalili","year":"2021","journal-title":"Subst. Abus. Treat. Prev. Policy"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.drugalcdep.2015.08.028","article-title":"Self-reported use of novel psychoactive substances in a US nationally representative survey: Prevalence, correlates, and a call for new survey methods to prevent underreporting","volume":"156","author":"Palamar","year":"2015","journal-title":"Drug Alcohol Depend."},{"key":"ref_85","first-page":"923290","article-title":"Sources of Error in Substance Use Prevalence Surveys","volume":"2014","author":"Johnson","year":"2014","journal-title":"Int. Sch. Res. Not."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/22\/15261\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:21:19Z","timestamp":1760145679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/22\/15261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,18]]},"references-count":85,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["ijerph192215261"],"URL":"https:\/\/doi.org\/10.3390\/ijerph192215261","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,18]]}}}