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The aim of the present study was twofold: first, to assess the role of family climate, concerning participants\u2019 LGBT+ status during lockdown restrictions, in mediating the impact of the COVID-19 pandemic on personal quality of life and mental health (stress, depression, and anxiety); second, to assess how individual stable traits can moderate the relationship between the individual impact of COVID-19 on mental health outcomes. A total of 407 young adults aged 18 to 35 (M age = 25.03 years; SD = 4.68) who self-identified as being part of a sexual or gender minority took part in this study. Results highlight the association between negative family climate and internalizing symptoms of psychological distress, and its role as a partial mediator of the relationship between the impact of the COVID-19 pandemic at the individual level and mental health outcomes. Additionally, low personality trait levels of neuroticism significantly decreased the strength of the relationship between LGBT+ status during blocking restrictions and internalizing symptoms.<\/jats:p>","DOI":"10.3390\/ijerph192315795","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T03:28:49Z","timestamp":1669606129000},"page":"15795","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Influence of the COVID-19 Pandemic on Italian LGBT+ Young Adults\u2019 Mental Health: The Role of Neuroticism and Family Climate"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4218-1068","authenticated-orcid":false,"given":"Marina","family":"Miscioscia","sequence":"first","affiliation":[{"name":"Department of Developmental Psychology and Socialization, University of Padua, 35131 Padua, Italy"},{"name":"Department of Women\u2019s and Children\u2019s Health, University of Padua, 35128 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4017-4251","authenticated-orcid":false,"given":"Mikael","family":"Poli","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychology and Socialization, University of Padua, 35131 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9729-9234","authenticated-orcid":false,"given":"Alessio","family":"Gubello","sequence":"additional","affiliation":[{"name":"Faculty of Psychology and Education Sciences, Universit\u00e9 Libre de Bruxelles, 1050 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Simonelli","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychology and Socialization, University of Padua, 35131 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Gatta","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, University of Padua, 35128 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6402-3680","authenticated-orcid":false,"given":"Jorge","family":"Gato","sequence":"additional","affiliation":[{"name":"Faculty of Psychology and Education Sciences and Center for Psychology, University of Porto, Rua Alfredo Allen, 4200-135 Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4525-6267","authenticated-orcid":false,"given":"Paola","family":"Rigo","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychology and Socialization, University of Padua, 35131 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jad.2022.07.011","article-title":"The global evolution of mental health problems during the COVID-19 pandemic: A systematic review and meta-analysis of longitudinal studies","volume":"315","author":"Farahi","year":"2022","journal-title":"J. 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