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This study examined the microbiome\u2013gut\u2013brain axis and dementia-related research from a bibliometric perspective. Methods: A search for original research and review articles on the microbiome\u2013gut\u2013brain axis and dementia was conducted in the Web of Science Core Collection (WOSCC) database. The R package \u201cbibliometrix\u201d was used to collect information on countries, institutions, authors, journals, and keywords. VOSviewer software was used to visualize the co-occurrence network of keywords. Results: Overall, 494 articles met the study inclusion criteria, with an average of 29.64 citations per article. Corresponding authors of published articles were mainly from China, the United States and Italy. Zhejiang University in China and Kyung Hee University in Korea were the most active institutions, while the Journal of Alzheimer\u2019s Disease and Nutrients published the most articles in this field. Expected main search terms, \u201cParkinson disease\u201d and \u201cchain fatty-acids\u201d were high-frequency keywords that indicate current and future research directions in this field. Conclusions: This bibliometric study helped researchers to identify the key topics and trends in the microbiome\u2013gut\u2013brain axis and dementia-related research. High-frequency keywords identified in this study reflect current trends and possible future directions in this field related to methodologies, mechanisms and populations of interest.<\/jats:p>","DOI":"10.3390\/ijerph192416549","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T04:46:46Z","timestamp":1670561206000},"page":"16549","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Microbiome\u2013Gut\u2013Brain Axis and Dementia: A Bibliometric Analysis"],"prefix":"10.3390","volume":"19","author":[{"given":"He-Li","family":"Sun","sequence":"first","affiliation":[{"name":"Unit of Psychiatry, Department of Public Health and Medicinal Administration, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China"},{"name":"Centre for Cognitive and Brain Sciences, University of Macau, Macao SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Feng","sequence":"additional","affiliation":[{"name":"The National Clinical Research Center for Mental Disorders, Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100054, China"},{"name":"Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinge","family":"Zhang","sequence":"additional","affiliation":[{"name":"The National Clinical Research Center for Mental Disorders, Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100054, China"},{"name":"Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Centre for Cognitive and Brain Sciences, University of Macau, Macao SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Centre for Cognitive and Brain Sciences, University of Macau, Macao SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2005-9504","authenticated-orcid":false,"given":"Zhaohui","family":"Su","sequence":"additional","affiliation":[{"name":"School of Public Health, Institute for Human Rights, Southeast University, Nanjing 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5878-9193","authenticated-orcid":false,"given":"Teris","family":"Cheung","sequence":"additional","affiliation":[{"name":"School of Nursing, Hong Kong Polytechnic University, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Macau, Macao SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sha","family":"Sha","sequence":"additional","affiliation":[{"name":"The National Clinical Research Center for Mental Disorders, Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100054, China"},{"name":"Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Tao","family":"Xiang","sequence":"additional","affiliation":[{"name":"Unit of Psychiatry, Department of Public Health and Medicinal Administration, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China"},{"name":"Centre for Cognitive and Brain Sciences, University of Macau, Macao SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.4161\/gmic.1.4.12306","article-title":"Evaluating the latest high-throughput molecular techniques for the exploration of microbial gut communities","volume":"1","author":"Claesson","year":"2010","journal-title":"Gut Microbes"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1080\/19490976.2019.1638722","article-title":"Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health","volume":"11","author":"Parker","year":"2020","journal-title":"Gut Microbes"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12974-019-1494-4","article-title":"Antibiotics, gut microbiota, and Alzheimer\u2019s disease","volume":"16","author":"Angelucci","year":"2019","journal-title":"J. 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