{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T11:26:15Z","timestamp":1793618775350,"version":"4.5.0"},"reference-count":58,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: The likelihood of experiencing the impact of chronic disease rises with age, and cumulative functional deficits over time increase the risk of frailty in older adults. The exact causes of frailty are not clear, and research is needed to identify appropriate intervention measures to reduce risk of developing frailty in old age. Objective: To review the evidence on the relationship between frailty, dental status and chronic periodontitis and to determine if improvements in oral health of older adults can contribute to reversal of frailty. Results: The oral cavity is the entry point to the gastro-intestinal tract, and natural teeth facilitate efficient mastication of food prior to swallowing and subsequent digestion. The loss of natural teeth, which is gradual and cumulative over the life course, is associated with diminished nutritional intake, especially in older adults. Furthermore, chronic periodontitis has been postulated as a risk factor for frailty. The evidence supporting a strong relationship between oral health status and frailty is not clearcut. Cross sectional studies suggest an association with missing teeth and chronic periodontal inflammation. However, there are very few longitudinal studies and accordingly, it is not currently possible to claim a causal relationship. As yet, there is no evidence to suggest that improvements in oral health contribute to reversal of frailty. Conclusion: Longitudinal studies with robust designs are required to better inform the relationship across functional dentition, chronic periodontitis and frailty in older adults.<\/jats:p>","DOI":"10.3390\/ijerph20010502","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T08:42:22Z","timestamp":1672216942000},"page":"502","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Functional Dentition, Chronic Periodontal Disease and Frailty in Older Adults\u2014A Narrative Review"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6579-4233","authenticated-orcid":false,"given":"Gabriel Lee Keng","family":"Yan","sequence":"first","affiliation":[{"name":"Faculty of Dentistry, National University of Singapore, Singapore 119085, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei Na","family":"Tan","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, National University of Singapore, Singapore 119085, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mun Loke","family":"Wong","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, National University of Singapore, Singapore 119085, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong Meng","family":"Tay","sequence":"additional","affiliation":[{"name":"National University Centre for Oral Health, Singapore 119085, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5873-2728","authenticated-orcid":false,"given":"Patrick Finbarr","family":"Allen","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, National University of Singapore, Singapore 119085, Singapore"},{"name":"Department of Restorative Dentistry, Cork Dental School and Hospital, University College Cork, T12 DC4A Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"key":"ref_1","unstructured":"WHO (2017). 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