{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:49:05Z","timestamp":1789566545824,"version":"build-2803163510"},"reference-count":24,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T00:00:00Z","timestamp":1672272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Research Project of Anhui Universities","award":["KJ2021A0262"],"award-info":[{"award-number":["KJ2021A0262"]}]},{"name":"Natural Science Research Project of Anhui Universities","award":["2021YFC250104"],"award-info":[{"award-number":["2021YFC250104"]}]},{"name":"Natural Science Research Project of Anhui Universities","award":["2020JWZZHL-04"],"award-info":[{"award-number":["2020JWZZHL-04"]}]},{"name":"Natural Science Research Project of Anhui Universities","award":["2022GYKJ10"],"award-info":[{"award-number":["2022GYKJ10"]}]},{"name":"National Key Research and Development Program project","award":["KJ2021A0262"],"award-info":[{"award-number":["KJ2021A0262"]}]},{"name":"National Key Research and Development Program project","award":["2021YFC250104"],"award-info":[{"award-number":["2021YFC250104"]}]},{"name":"National Key Research and Development Program project","award":["2020JWZZHL-04"],"award-info":[{"award-number":["2020JWZZHL-04"]}]},{"name":"National Key Research and Development Program project","award":["2022GYKJ10"],"award-info":[{"award-number":["2022GYKJ10"]}]},{"name":"Emergency and Critical Care Nursing Specialty Construction Project of the First Affiliated Hospital of Anhui Medical University","award":["KJ2021A0262"],"award-info":[{"award-number":["KJ2021A0262"]}]},{"name":"Emergency and Critical Care Nursing Specialty Construction Project of the First Affiliated Hospital of Anhui Medical University","award":["2021YFC250104"],"award-info":[{"award-number":["2021YFC250104"]}]},{"name":"Emergency and Critical Care Nursing Specialty Construction Project of the First Affiliated Hospital of Anhui Medical University","award":["2020JWZZHL-04"],"award-info":[{"award-number":["2020JWZZHL-04"]}]},{"name":"Emergency and Critical Care Nursing Specialty Construction Project of the First Affiliated Hospital of Anhui Medical University","award":["2022GYKJ10"],"award-info":[{"award-number":["2022GYKJ10"]}]},{"name":"Anhui Zhongji Guoyi Medical Technology Co., Ltd.","award":["KJ2021A0262"],"award-info":[{"award-number":["KJ2021A0262"]}]},{"name":"Anhui Zhongji Guoyi Medical Technology Co., Ltd.","award":["2021YFC250104"],"award-info":[{"award-number":["2021YFC250104"]}]},{"name":"Anhui Zhongji Guoyi Medical Technology Co., Ltd.","award":["2020JWZZHL-04"],"award-info":[{"award-number":["2020JWZZHL-04"]}]},{"name":"Anhui Zhongji Guoyi Medical Technology Co., Ltd.","award":["2022GYKJ10"],"award-info":[{"award-number":["2022GYKJ10"]}]},{"name":"Open Program of the Hospital Management Institute, Anhui Medical University","award":["KJ2021A0262"],"award-info":[{"award-number":["KJ2021A0262"]}]},{"name":"Open Program of the Hospital Management Institute, Anhui Medical University","award":["2021YFC250104"],"award-info":[{"award-number":["2021YFC250104"]}]},{"name":"Open Program of the Hospital Management Institute, Anhui Medical University","award":["2020JWZZHL-04"],"award-info":[{"award-number":["2020JWZZHL-04"]}]},{"name":"Open Program of the Hospital Management Institute, Anhui Medical University","award":["2022GYKJ10"],"award-info":[{"award-number":["2022GYKJ10"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>In China, stroke is characterized by high incidence, recurrence, disability, economic burden, and mortality. Regular and effective medication therapy can reduce stroke recurrence. High medication literacy is vital for the success of tertiary prevention measures aimed at preventing recurrence and minimizing disability. A cross-sectional survey using a medication literacy questionnaire was conducted between January and May 2022 on 307 inpatients of a Class III Grade A hospital in Hefei, Anhui Province, China. The demographic and clinical data of the patients were obtained from medical records. The health literacy of the patients was moderate, with 36.8% exhibiting adequate medication literacy. Univariate analysis identified significant differences in the medication literacy of the patients, depending on education level, annual income, family history of stroke, number of health problems, age, daily medication times, and brain surgery history. Multiple regression analysis revealed that education level, annual income, family history of stroke, and number of health problems significantly influenced medication literacy. In patients with stroke who are older and have a low education level, more health problems, no history of surgery, or no family history of stroke or medication guidance, medication knowledge and attitude can be improved to enhance medication safety and guarantee tertiary-level prevention of stroke.<\/jats:p>","DOI":"10.3390\/ijerph20010620","type":"journal-article","created":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T03:31:17Z","timestamp":1672371077000},"page":"620","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Medication Literacy in Chinese Patients with Stroke and Associated Factors: A Cross-Sectional Study"],"prefix":"10.3390","volume":"20","author":[{"given":"Xiao","family":"Chang","sequence":"first","affiliation":[{"name":"The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Wang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Wang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houmian","family":"Tu","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiping","family":"Gong","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haifeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Health Management, Anhui Medical University, Hefei 230032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e897","DOI":"10.1016\/S2468-2667(21)00228-0","article-title":"Temporal trend and attributable risk factors of stroke burden in China, 1990-2019: An analysis for the Global Burden of Disease Study 2019","volume":"6","author":"Ma","year":"2021","journal-title":"Lancet Public Health"},{"key":"ref_2","unstructured":"GBD 2019 Stroke Collaborators (2021). Global, regional, and national burden of stroke and its risk factors, 1990\u20132019: A systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol., 20, 795\u2013820."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"722711","DOI":"10.3389\/fneur.2021.722711","article-title":"Association between Patient Activation and Medication Adherence in Patients with Stroke: A Cross-Sectional Study","volume":"12","author":"Sui","year":"2021","journal-title":"Front. Neurol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Donneyong, M.M., Fischer, M.A., Langston, M.A., Joseph, J.J., Juarez, P.D., Zhang, P., and Kline, D.M. (2021). Examining the Drivers of Racial\/Ethnic Disparities in Non-Adherence to Antihypertensive Medications and Mortality Due to Heart Disease and Stroke: A County-Level Analysis. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph182312702"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3390\/ijerph16020196","article-title":"Adherence to Treatment in Stroke Patients","volume":"16","author":"Emmanouela","year":"2019","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"P\u00e9rez-Jover, V., Mira, J.J., Carratala-Munuera, C., Gil-Guillen, V.F., Basora, J., L\u00f3pez-Pineda, A., and Orozco-Beltr\u00e1n, D. (2018). Inappropriate use of medication by elderly, polymedicated, or multipathological patients with chronic diseases. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15020310"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"202","DOI":"10.21037\/atm-22-453","article-title":"Evidence-based summary for the safety of multiple medication in elderly patients with ischemic stroke","volume":"10","author":"Tian","year":"2022","journal-title":"Ann. Transl. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/rnj.194","article-title":"SAFE Medication Management for Patients with Physical Impairments of Stroke, Part One","volume":"40","author":"Yetzer","year":"2015","journal-title":"Rehabil. Nurs."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/rnj.286","article-title":"SAFE Medication Management for Patients with Physical Impairments of Stroke, Part Two","volume":"42","author":"Yetzer","year":"2017","journal-title":"Rehabil. Nurs."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"822","DOI":"10.3389\/fphar.2019.00822","article-title":"Association Between Medication Literacy and Medication Adherence Among Patients with Hypertension","volume":"10","author":"Shi","year":"2019","journal-title":"Front. Pharmacol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.3389\/fphar.2019.01537","article-title":"Relationship Between Medication Literacy and Medication Adherence in patients with Coronary Heart Disease in Changsha, China","volume":"10","author":"Zheng","year":"2019","journal-title":"Front. Pharmacol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"569092","DOI":"10.3389\/fphar.2020.569092","article-title":"Mediating Effect of Self-Efficacy on the Relationship between Medication Literacy and Medication Adherence among Patients with Hypertension","volume":"11","author":"Shen","year":"2020","journal-title":"Front. Pharmacol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"691983","DOI":"10.3389\/fphar.2021.691983","article-title":"Relationship Between Medication Literacy and Frailty in Elderly patients with Coronary Heart Disease: A Cross-Sectional Study in China","volume":"12","author":"Qu","year":"2021","journal-title":"Front. Pharmacol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.sapharm.2017.11.005","article-title":"Defining and identifying concepts of medication literacy: An international perspective","volume":"14","author":"Pouliot","year":"2017","journal-title":"Res. Soc. Adm. Pharm."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1016\/j.sapharm.2021.06.003","article-title":"Medication literacy: A conceptual model","volume":"18","author":"Nascimento","year":"2022","journal-title":"Res. Soc. Adm Pharm."},{"key":"ref_16","first-page":"335","article-title":"Medication literacy: Why pharmacists should pay attention","volume":"69","author":"Pouliot","year":"2016","journal-title":"Can. J. Hosp. Pharm."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e231","DOI":"10.1331\/JAPhA.2012.11264","article-title":"Medication literacy in Spanish and English: Psychometric evaluation of a new assessment tool","volume":"52","author":"Sauceda","year":"2012","journal-title":"J. Am. Pharm. Assoc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1016\/j.asjsur.2022.04.054","article-title":"Clinical value of computerized tomography perfusion imaging in the diagnosis of acute ischemic stroke","volume":"45","author":"Hu","year":"2022","journal-title":"Asian J. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1177\/0300060516676726","article-title":"Medication literacy status of outpatients in ambulatory care settings in Changsha, China","volume":"45","author":"Zheng","year":"2017","journal-title":"J. Int. Med. Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s11739-019-02187-0","article-title":"The status of medication literacy and associated factors of hypertensive patients in China: A cross-sectional study","volume":"15","author":"Ma","year":"2020","journal-title":"Intern. Emerg. Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"705783","DOI":"10.3389\/fcvm.2021.705783","article-title":"Association Between Social Support and Medication Literacy in Chinese Patients with Coronary Heart Disease","volume":"8","author":"Qiao","year":"2021","journal-title":"Front. Cardiovasc. Med."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"e411","DOI":"10.1016\/S2214-109X(20)30004-8","article-title":"Correction to: Post-discharge prognosis of patients admitted to hospital for heart failure by world region, and national level of income and income disparity (REPORT-HF): A cohort study","volume":"8","author":"Tromp","year":"2020","journal-title":"Lancet Glob. Health"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Langlois, S., and Goudreau, J. (2022). Motivational Interviewing Implementation in Primary Care: A \u201cTerrifying Challenge\u201d Becoming a \u201cProfessional Revelation\u201d. Health Educ. Behav., 13.","DOI":"10.1177\/10901981221139808"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1001\/jamainternmed.2022.5074","article-title":"Effect of Computer-Tailored Print Feedback, Motivational Interviewing, and Motivational Enhancement Therapy on Engagement in Advance Care Planning: A Randomized Clinical Trial","volume":"182","author":"Fried","year":"2022","journal-title":"JAMA Intern. Med."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/1\/620\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:55:49Z","timestamp":1760147749000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/1\/620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,29]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["ijerph20010620"],"URL":"https:\/\/doi.org\/10.3390\/ijerph20010620","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,29]]}}}