{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:34:27Z","timestamp":1790836467513,"version":"4.1.0"},"reference-count":27,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,21]],"date-time":"2023-01-21T00:00:00Z","timestamp":1674259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"INAIL Italian Workers\u2019 Compensation Authority"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Introduction. Formaldehyde, a colorless and highly irritating substance, causes cancer of the nasopharynx and leukemia. Furthermore, it is one of the environmental mutagens to which humans are most abundantly exposed. Acetaldehyde was recently classified as carcinogen class 1B and mutagen class 2 in Annex VI EC regulation. Occupational exposure to the two aldehydes occurs in a wide variety of occupations and industries. The aim of this study is to deepen exposure to the two aldehydes in the non-traditional productive sectors of bakeries and pastry producers. Methods. The evaluation of exposure to formaldehyde and acetaldehyde was conducted in Italy in 2019, in specific tasks and positions of 11 bakeries and pastry producers (115 measures, of which 57.4% were in fixed positions and the rest were personal air sampling). The measurements were performed using Radiello\u00a9 radial diffusion samplers. A logarithmic transformation of the data was performed, and the correlation between the two substances was calculated. Moreover, linear models considering the log-formaldehyde as the outcome and adjusting for log-acetaldehyde values were used. Results. The study identified high levels of acetaldehyde and formaldehyde exposure in the monitored workplaces. Higher mean values were observed in the leavening phase (8.39 \u00b5g\/m3 and 3.39 \u00b5g\/m3 for log-transformed data acetaldehyde and formaldehyde, respectively). The adjusted univariate analyses show statistically significant factors for formaldehyde as the presence of yeast, the presence of type 1 flour, the use of barley, the use of fats, the type of production, the use of spelt, and the presence of type 0 flour. Conclusions. The measurements confirmed the release of formaldehyde and acetaldehyde in bakeries and pastry industries, especially in some phases of the work process, such as leavening.<\/jats:p>","DOI":"10.3390\/ijerph20031983","type":"journal-article","created":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T02:01:02Z","timestamp":1674439262000},"page":"1983","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Formaldehyde and Acetaldehyde Exposure in \u201cNon-Traditional\u201d Occupational Sectors: Bakeries and Pastry Producers"],"prefix":"10.3390","volume":"20","author":[{"given":"Lucia","family":"Miligi","sequence":"first","affiliation":[{"name":"Occupational and Environmental Epidemiology Branch, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4198-7035","authenticated-orcid":false,"given":"Sara","family":"Piro","sequence":"additional","affiliation":[{"name":"Occupational and Environmental Epidemiology Branch, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9114-5816","authenticated-orcid":false,"given":"Chiara","family":"Airoldi","sequence":"additional","affiliation":[{"name":"Occupational and Environmental Epidemiology Branch, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Di Rico","sequence":"additional","affiliation":[{"name":"Local Health Unit AUSL Modena, SPSAL-Department of Public Health, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Ricci","sequence":"additional","affiliation":[{"name":"Local Health Unit AUSL Modena, SPSAL-Department of Public Health, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy Ivan","family":"Paredes Alpaca","sequence":"additional","affiliation":[{"name":"Local Health Unit AUSL Modena, SPSAL-Department of Public Health, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"De Pasquale","sequence":"additional","affiliation":[{"name":"Local Health Unit AUSL Modena, SPSAL-Department of Public Health, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Veraldi","sequence":"additional","affiliation":[{"name":"Occupational and Environmental Epidemiology Branch, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Ranucci","sequence":"additional","affiliation":[{"name":"Occupational and Environmental Epidemiology Branch, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6364-2471","authenticated-orcid":false,"given":"Stefania","family":"Massari","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers\u2019 Compensation Authority (INAIL), 00143 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9068-2137","authenticated-orcid":false,"given":"Alessandro","family":"Marinaccio","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers\u2019 Compensation Authority (INAIL), 00143 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Stoppa","sequence":"additional","affiliation":[{"name":"Occupational and Environmental Epidemiology Branch, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Cenni","sequence":"additional","affiliation":[{"name":"Unit of Occupational Hygiene and Toxicology, Public Health Laboratory, Department of Prevention, AUSL South-East Tuscany, 53100 Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Trane","sequence":"additional","affiliation":[{"name":"Unit of Occupational Hygiene and Toxicology, Public Health Laboratory, Department of Prevention, AUSL South-East Tuscany, 53100 Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Peruzzi","sequence":"additional","affiliation":[{"name":"Unit of Occupational Hygiene and Toxicology, Public Health Laboratory, Department of Prevention, AUSL South-East Tuscany, 53100 Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina","family":"Aprea","sequence":"additional","affiliation":[{"name":"Unit of Occupational Hygiene and Toxicology, Public Health Laboratory, Department of Prevention, AUSL South-East Tuscany, 53100 Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,21]]},"reference":[{"key":"ref_1","unstructured":"International Agency for Research on Cancer (2012). 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