{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T09:26:10Z","timestamp":1784366770200,"version":"3.55.0"},"reference-count":93,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T00:00:00Z","timestamp":1674432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Postoperative pain is common following spine surgery, particularly complex procedures. The main anesthetic efforts are focused on applying multimodal analgesia beforehand, and regional anesthesia is a critical component of it. The purpose of this study is to examine the existing techniques for regional anesthesia in cervical spine surgery and to determine their effect and safety on pain reduction and postoperative patient\u2019s recovery. The electronic databases were searched for all literature pertaining to cervical nerve block procedures. The following peripheral, cervical nerve blocks were selected and described: paravertebral block, cervical plexus clock, paraspinal interfascial plane blocks such as multifidus cervicis, retrolaminar, inter-semispinal and interfacial, as well as erector spinae plane block and stellate ganglion block. Clinicians should choose more superficial techniques in the cervical region, as they have been shown to be comparably effective and less hazardous compared to paravertebral blocks<\/jats:p>","DOI":"10.3390\/ijerph20032098","type":"journal-article","created":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T01:29:45Z","timestamp":1674523785000},"page":"2098","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Ultrasound-Guided Blocks for Spine Surgery: Part 1\u2014Cervix"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3714-0117","authenticated-orcid":false,"given":"Kamil","family":"Adamczyk","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Intensive Therapy, Central Clinical Hospital of the Ministry of Interior and Administration in Warsaw, 02-507 Warsaw, Poland"},{"name":"Department of Anaesthesiology, National Institute of Geriatrics, Rheumatology and Rehabilitation in Warsaw, 02-637 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3629-7523","authenticated-orcid":false,"given":"Kamil","family":"Koszela","sequence":"additional","affiliation":[{"name":"Neuroorthopedics and Neurology Clinic and Polyclinic, National Institute of Geriatrics, Rheumatology and Rehabilitation, 02-637 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artur","family":"Zaczy\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Central Clinical Hospital of the Ministry of Interior and Administration in Warsaw, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Nied\u017awiecki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Central Clinical Hospital of the Ministry of Interior and Administration in Warsaw, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sybilla","family":"Brzozowska-Ma\u0144kowska","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, National Institute of Geriatrics, Rheumatology and Rehabilitation in Warsaw, 02-637 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1947-2775","authenticated-orcid":false,"given":"Robert","family":"Gasik","sequence":"additional","affiliation":[{"name":"Neuroorthopedics and Neurology Clinic and Polyclinic, National Institute of Geriatrics, Rheumatology and Rehabilitation, 02-637 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/ACO.0000000000000494","article-title":"Management of Complex Spine Surgery","volume":"30","author":"Lamperti","year":"2017","journal-title":"Curr. Opin. Anaesthesiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.jocn.2015.01.003","article-title":"Best Evidence in Multimodal Pain Management in Spine Surgery and Means of Assessing Postoperative Pain and Functional Outcomes","volume":"22","author":"Devin","year":"2015","journal-title":"J. Clin. Neurosci."},{"key":"ref_3","first-page":"557","article-title":"Analgesia after surgery of the spine in adults and adolescents","volume":"43","author":"Bernard","year":"1995","journal-title":"Cah. Anesthesiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.spinee.2010.10.023","article-title":"An Evidence-Based Clinical Guideline for the Diagnosis and Treatment of Cervical Radiculopathy from Degenerative Disorders","volume":"11","author":"Bono","year":"2011","journal-title":"Spine J."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1007\/s00586-017-5121-8","article-title":"National Clinical Guidelines for Non-Surgical Treatment of Patients with Recent Onset Neck Pain or Cervical Radiculopathy","volume":"26","author":"Kjaer","year":"2017","journal-title":"Eur. Spine J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.berh.2011.01.019","article-title":"The Epidemiology of Neck Pain","volume":"24","author":"Hoy","year":"2010","journal-title":"Best Pract. Res. Clin. Rheumatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"E251","DOI":"10.1097\/BSD.0000000000000284","article-title":"Cervical Radiculopathy: Epidemiology, Etiology, Diagnosis, and Treatment","volume":"28","author":"Woods","year":"2015","journal-title":"J. Spinal Disord Tech."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1097\/BRS.0000000000000307","article-title":"Preoperative Factors Affecting Length of Stay after Elective ACDF with and without Corpectomy: A Multivariate Analysis of an Academic Center Cohort","volume":"39","author":"Basques","year":"2014","journal-title":"Spine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"878","DOI":"10.3171\/2015.8.SPINE14284","article-title":"Anterior Cervical Discectomy and Fusion in the Outpatient Ambulatory Surgery Setting Compared with the Inpatient Hospital Setting: Analysis of 1000 Consecutive Cases","volume":"24","author":"Adamson","year":"2016","journal-title":"J. Neurosurg. Spine"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"E34","DOI":"10.1097\/BSD.0000000000000080","article-title":"Factors Affecting Length of Stay and Complications After Elective Anterior Cervical Discectomy and Fusion: A Study of 2164 Patients From The American College of Surgeons National Surgical Quality Improvement Project Database (ACS NSQIP)","volume":"29","author":"Gruskay","year":"2016","journal-title":"Clin. Spine Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1097\/BRS.0000000000001988","article-title":"Outpatient Anterior Cervical Discectomy and Fusion Is Associated with Fewer Short-Term Complications in One- A Nd Two-Level Cases","volume":"42","author":"Fu","year":"2017","journal-title":"Spine"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"E648","DOI":"10.1097\/BRS.0000000000001925","article-title":"Best Practices for Outpatient Anterior Cervical Surgery","volume":"42","author":"Mohandas","year":"2017","journal-title":"Spine"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1097\/BRS.0000000000001992","article-title":"Multimodal Analgesia Versus Intravenous Patient-Controlled Analgesia for Minimally Invasive Transforaminal Lumbar Interbody Fusion Procedures","volume":"42","author":"Singh","year":"2017","journal-title":"Spine"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1007\/s00586-013-2826-1","article-title":"A Comprehensive Multimodal Pain Treatment Reduces Opioid Consumption after Multilevel Spine Surgery","volume":"22","author":"Mathiesen","year":"2013","journal-title":"Eur. Spine J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1213\/01.ANE.0000068822.10113.9E","article-title":"Postoperative Pain Experience: Results from a National Survey Suggest Postoperative Pain Continues to Be Undermanaged","volume":"97","author":"Apfelbaum","year":"2003","journal-title":"Anesth. Analg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1007\/s00132-014-3040-5","article-title":"Pre- and Postoperative Fast-Track Treatment Concepts in Spinal Surgery: Patient Information and Patient Cooperation","volume":"43","author":"Fleege","year":"2014","journal-title":"Orthopade"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1097\/ALN.0000000000003143","article-title":"Multimodal Analgesic Regimen for Spine SurgeryA Randomized Placebo-Controlled Trial","volume":"132","author":"Maheshwari","year":"2020","journal-title":"Anesthesiology"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/gerona\/glp145","article-title":"Surgery-Induced Inflammation in Relation to Age, Muscle Endurance, and Self-Perceived Fatigue","volume":"65","author":"Bautmans","year":"2010","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.pain.2007.07.026","article-title":"The Roles of Sodium Channels in Nociception: Implications for Mechanisms of Pain","volume":"131","author":"Cummins","year":"2007","journal-title":"Pain"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3389\/fcimb.2017.00217","article-title":"Multiple Phenotypic Changes Define Neutrophil Priming","volume":"7","author":"Miralda","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/oxfordjournals.bja.a013387","article-title":"Wound Infiltration with Bupivacaine after Surgery to the Cervical Spine Using a Posterior Approach","volume":"84","author":"Pobereskin","year":"2000","journal-title":"Br. J. Anaesth."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1469-7580.2006.00537.x","article-title":"Clinically Oriented Anatomy","volume":"208","author":"Sperber","year":"2006","journal-title":"J. Anat."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"5","DOI":"10.4103\/0970-9185.76608","article-title":"Paravertebral Block","volume":"27","author":"Krishnan","year":"2011","journal-title":"J. Anaesthesiol. Clin. Pharmacol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1007\/BF01711404","article-title":"Other Experiences with Sympathectomy","volume":"2","author":"Kappis","year":"1923","journal-title":"Klin. Wochenschr."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/j.1365-2044.1979.tb06363.x","article-title":"Paravertebral Thoracic Block-a Reappraisal","volume":"34","author":"EASON","year":"1979","journal-title":"Anaesthesia"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.rapm.2003.10.005","article-title":"Paravertebral Approach to the Brachial Plexus: An Anatomic Improvement in Technique","volume":"28","author":"Boezaart","year":"2003","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/AAP.0b013e3181933af7","article-title":"Interscalene Perineural Catheter Placement Using an Ultrasound-Guided Posterior Approach","volume":"34","author":"Mariano","year":"2009","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_28","first-page":"64","article-title":"Ultrasound-Guided Posterior Approach for the Placement of a Continuous Interscalene Catheter","volume":"34","author":"Antonakakis","year":"2009","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_29","unstructured":"Butterworth, J.F., Mackey, D.C., and Wasnick, J.D. (2022). Morgan & Mikhail\u2019s Clinical Anesthesiology, McGraw-Hill Education. [7th ed.]."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1213\/01.ane.0000247714.67531.77","article-title":"Please Don\u2019t Blame the Block","volume":"104","author":"Boezaart","year":"2007","journal-title":"Anesth. Analg."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"29945724","DOI":"10.1259\/dmfr\/29945724","article-title":"Ultrasound-Guided Combined Intermediate and Deep Cervical Plexus Nerve Block for Regional Anaesthesia in Oral and Maxillofacial Surgery","volume":"42","author":"Perisanidis","year":"2013","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_32","first-page":"971","article-title":"A Simple Method for Blocking the Deep Cervical Nerve Plexus Using an Ultrasound-Guided Technique","volume":"39","author":"Saranteas","year":"2011","journal-title":"Anaesth. Intensive Care"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"4654803","DOI":"10.1155\/2017\/4654803","article-title":"Ultrasound-Guided versus Fluoroscopy-Guided Deep Cervical Plexus Block for the Treatment of Cervicogenic Headache","volume":"2017","author":"Wan","year":"2017","journal-title":"Biomed. Res. Int."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1177\/0310057X0603400201","article-title":"Ultrasound Guided Deep Cervical Plexus Block","volume":"34","author":"Sandeman","year":"2006","journal-title":"Anaesth. Intensive. Care"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1111\/j.1365-2044.2001.2084-2.x","article-title":"Somatic Paravertebral Nerve Blockade. Incidence of Failed Block and Complications","volume":"56","author":"Naja","year":"2001","journal-title":"Anaesthesia"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1097\/00000542-200012000-00033","article-title":"Permanent Loss of Cervical Spinal Cord Function Associated with Interscalene Block Performed under General Anesthesia","volume":"93","author":"Kleopa","year":"2000","journal-title":"Anesthesiology"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1515\/med-2019-0112","article-title":"Resuscitation Following a Bupivacaine Injection for a Cervical Paravertebral Block","volume":"14","author":"Vosylius","year":"2020","journal-title":"Open Med."},{"key":"ref_38","first-page":"ons99","article-title":"Postoperative Continuous Paravertebral Anesthetic Infusion for Pain Control in Posterior Cervical Spine Surgery: A Case-Control Study","volume":"66","author":"Elder","year":"2010","journal-title":"Neurosurgery"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1213\/01.ANE.0000180269.86543.98","article-title":"Carotid Endarterectomy Using Single Injection Posterior Cervical Paravertebral Block","volume":"101","author":"Boezaart","year":"2005","journal-title":"Anesth. Analg."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1213\/00000539-199912000-00006","article-title":"A Comparison of Two Techniques for Cervical Plexus Blockade: Evaluation of Efficacy and Systemic Toxicity","volume":"89","author":"Merle","year":"1999","journal-title":"Anesth. Analg."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"e6119","DOI":"10.1097\/MD.0000000000006119","article-title":"Cervical Plexus Anesthesia versus General Anesthesia for Anterior Cervical Discectomy and Fusion Surgery: A Randomized Clinical Trial","volume":"96","author":"Wang","year":"2017","journal-title":"Medicine"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s12630-015-0382-3","article-title":"L\u2019effet d\u2019un Bloc Du Plexus Cervical Superficiel Sur La Qualit\u00e9 de La R\u00e9cup\u00e9ration Postop\u00e9ratoire Apr\u00e8s Une Discectomie Cervicale Ant\u00e9rieure et Fusion: Une \u00c9tude Randomis\u00e9e Contr\u00f4l\u00e9e","volume":"62","author":"Mariappan","year":"2015","journal-title":"Can. J. Anesth."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1007\/s12630-015-0431-y","article-title":"Thoracolumbar Interfascial Plane (TLIP) Block: A Pilot Study in Volunteers","volume":"62","author":"Hand","year":"2015","journal-title":"Can. J. Anaesth."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.jclinane.2015.09.005","article-title":"Clinical Experiences of Ultrasound-Guided Thoracolumbar Interfascial Plane Block: A Clinical Experience","volume":"33","author":"Ueshima","year":"2016","journal-title":"J. Clin. Anesth."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jclinane.2015.11.019","article-title":"RETRACTED: Clinical Efficacy of Modified Thoracolumbar Interfascial Plane Block","volume":"30","author":"Ueshima","year":"2016","journal-title":"J. Clin. Anesth."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jclinane.2017.01.010","article-title":"RETRACTED: Blocking of Multiple Posterior Branches of Cervical Nerves Using a Cervical Interfascial Plane Block","volume":"38","author":"Ueshima","year":"2017","journal-title":"J. Clin. Anesth."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s12630-016-0767-y","article-title":"Multifidus Cervicis Plane Block Is Effective for Cervical Spine Surgery","volume":"64","author":"Ohgoshi","year":"2017","journal-title":"Can. J. Anesth."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00540-017-2439-7","article-title":"Novel Ultrasound-Guided Inter-Semispinal Plane Block: A Comparative Pilot Study in Healthy Volunteers","volume":"32","author":"Ohgoshi","year":"2018","journal-title":"J. Anesth."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/rapm-2021-102695","article-title":"Ultrasound-Guided Retrolaminar Cervical Block","volume":"47","author":"Hochberg","year":"2022","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s41983-020-00262-4","article-title":"The Efficacy of Ultrasound-Guided Multifidus Cervicis Plane Block versus Greater Occipital Nerve Block for Cervicogenic Headache","volume":"57","author":"Mohamed","year":"2021","journal-title":"Egypt. J. Neurol. Psychiatry Neurosurg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1129-2377-16-6","article-title":"Cervicogenic Headache: Too Important to Be Left Un-Diagnosed","volume":"16","author":"Fredriksen","year":"2015","journal-title":"J. Headache Pain"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2578396","DOI":"10.1155\/2019\/2578396","article-title":"Comparison of Clinical Efficacy and Anatomical Investigation between Retrolaminar Block and Erector Spinae Plane Block","volume":"2019","author":"Onishi","year":"2019","journal-title":"Biomed. Res. Int."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1111\/anae.14408","article-title":"Comparison of Injectate Spread and Nerve Involvement between Retrolaminar and Erector Spinae Plane Blocks in the Thoracic Region: A Cadaveric Study","volume":"73","author":"Yang","year":"2018","journal-title":"Anaesthesia"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1097\/BRS.0000000000004024","article-title":"A New Solution to an Old Problem: Ultrasound-Guided Cervical Retrolaminar Injection for Acute Cervical Radicular Pain: Prospective Clinical Pilot Study and Cadaveric Study","volume":"46","author":"Hochberg","year":"2021","journal-title":"Spine"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1097\/BRS.0000000000004397","article-title":"Ultrasound-Guided Cervical Retro-Laminar Block for Cervical Radicular Pain: A Comparative Analysis","volume":"47","author":"Khashan","year":"2022","journal-title":"Spine"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"110974","DOI":"10.1016\/j.jclinane.2022.110974","article-title":"Inter-Semispinal Plane (ISP) Block for Postoperative Analgesia Following Cervical Spine Surgery: A Prospective Randomized Controlled Trial","volume":"83","author":"Mostafa","year":"2022","journal-title":"J. Clin. Anesth."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s40140-019-00333-0","article-title":"Erector Spinae Plane (ESP) Block: A New Paradigm in Regional Anesthesia and Analgesia","volume":"9","author":"Chin","year":"2019","journal-title":"Curr. Anesthesiol. Rep."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/AAP.0000000000000451","article-title":"The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain","volume":"41","author":"Forero","year":"2016","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1136\/rapm-2019-100696","article-title":"Proposal to Standardize the Nomenclature for Paraspinal Interfascial Plane Blocks","volume":"44","author":"Xu","year":"2019","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"809","DOI":"10.4103\/ija.IJA_263_18","article-title":"Erector Spinae Plane Block: Relatively New Block on Horizon with a Wide Spectrum of Application\u2014A Case Series","volume":"62","author":"Jain","year":"2018","journal-title":"Indian J. Anaesth."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jclinane.2018.09.036","article-title":"The Erector Spinae Plane (ESP) Block: A Pooled Review of 242 Cases","volume":"53","author":"Tsui","year":"2019","journal-title":"J. Clin. Anesth."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"263","DOI":"10.4103\/sja.SJA_654_19","article-title":"Perioperative Analgesia with Erector Spinae Plane Block for Cervical Spine Instrumentation Surgery","volume":"14","author":"Goyal","year":"2020","journal-title":"Saudi. J. Anaesth."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"487","DOI":"10.4103\/0028-3886.314568","article-title":"Ultrasound-Guided Erector Spinae Plane Block for Perioperative Analgesia in Cervical and Thoracic Spine Surgeries\u2014A Case Series","volume":"69","author":"Goyal","year":"2021","journal-title":"Neurol. India"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1136\/rapm-2020-101807","article-title":"Cervical Erector Spinae Plane Block: Is It Feasible for Cervical Spine Surgeries?","volume":"46","author":"Kwon","year":"2021","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1136\/rapm-2020-101689","article-title":"Semispinalis Capitis Muscle Is a Key Factor in Defining Cervical Nerve Block Effect","volume":"46","author":"Ohgoshi","year":"2021","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1136\/rapm-2020-101788","article-title":"Novel Cervical Erector Spinae Plane Block: Interfascial Layers Remain Important in the Spread of Anesthetics","volume":"46","author":"Tsui","year":"2021","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_67","unstructured":"M\u00f6ller, T.B., and Reif, E. (2007). Pocket Atlas of Sectional Anatomy: Computed Tomography and Magnetic Resonance Imaging, Thieme Medical Publishers."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1007\/s00586-008-0696-8","article-title":"Surgical Anatomy of the Cervical Sympathetic Trunk during Anterolateral Approach to Cervical Spine","volume":"17","author":"Civelek","year":"2008","journal-title":"Eur. Spine J."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"372","DOI":"10.4103\/sja.SJA_617_16","article-title":"Ultrasound-Guided Stellate Ganglion Block for Resistant Ventricular Tachycardia","volume":"11","author":"Kumar","year":"2017","journal-title":"Saudi. J. Anaesth."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1111\/jce.14030","article-title":"Electrophysiologic Effects and Outcomes of Sympatholysis in Patients with Recurrent Ventricular Arrhythmia and Structural Heart Disease","volume":"30","author":"Cai","year":"2019","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Yoo, Y., Lee, C.S., Kim, Y.C., Moon, J.Y., and Finlayson, R.J. (2019). A Randomized Comparison between 4, 6 and 8 ML of Local Anesthetic for Ultrasound-Guided Stellate Ganglion Block. J. Clin. Med., 8.","DOI":"10.3390\/jcm8091314"},{"key":"ref_72","first-page":"467","article-title":"Effect of Early Stellate Ganglion Blockade for Facial Pain from Acute Herpes Zoster and Incidence of Postherpetic Neuralgia","volume":"15","author":"Makharita","year":"2012","journal-title":"Pain Physician"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"S302","DOI":"10.1016\/S0959-8049(16)30858-9","article-title":"Effects of Stellate Ganglion Block on Breast Cancer-Related Lymphedema: Comparison of Various Injectates","volume":"51","author":"Lee","year":"2015","journal-title":"Eur. J. Cancer"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1365-2044.1952.tb01454.x","article-title":"Stellate ganglion block","volume":"7","year":"1952","journal-title":"Anaesthesia"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/0002-9610(51)90324-8","article-title":"Stellate Ganglion Block: The Tissue Displacement Method","volume":"82","author":"Smith","year":"1951","journal-title":"Am. J. Surg."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.rapm.2006.03.006","article-title":"Skin Marking for Stellate Block With Fluoroscopic Guidance","volume":"31","author":"Ugur","year":"2006","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3389\/fnins.2019.00170","article-title":"CT-Guided Stellate Ganglion Pulsed Radiofrequency Stimulation for Facial and Upper Limb Postherpetic Neuralgia","volume":"13","author":"Ding","year":"2019","journal-title":"Front. Neurosci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1148\/radiology.188.3.8351337","article-title":"CT-Guided Injection of the Stellate Ganglion: Description of Technique and Efficacy of Sympathetic Blockade","volume":"188","author":"Erickson","year":"1993","journal-title":"Radiology"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/AAP.0b013e3181b494de","article-title":"Development and Validation of a New Technique for Ultrasound-Guided Stellate Ganglion Block","volume":"34","author":"Gofeld","year":"2009","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11916-014-0424-5","article-title":"Ultrasound-Guided Stellate Ganglion Block: Safety and Efficacy","volume":"18","author":"Narouze","year":"2014","journal-title":"Curr. Pain Headache Rep."},{"key":"ref_81","first-page":"323","article-title":"Ultrasound Imaging for Stellate Ganglion Block: Direct Visualization of Puncture Site and Local Anesthetic Spread: A Pilot Study","volume":"20","author":"Kapral","year":"1995","journal-title":"Reg. Anesth. J. Neural Blockade Obstet. Surg. Pain Control."},{"key":"ref_82","first-page":"1","article-title":"Stellate Ganglion Blockade-Techniques and Modalities","volume":"67","author":"Ghai","year":"2016","journal-title":"Acta Anaesthesiol. Belg."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"161","DOI":"10.4103\/1658-354X.168815","article-title":"Evaluation of New Approach to Ultrasound Guided Stellate Ganglion Block","volume":"10","author":"Ghai","year":"2016","journal-title":"Saudi. J. Anaesth."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"740","DOI":"10.3389\/fsurg.2021.797793","article-title":"Effects of Stellate Ganglion Block Through Different Approaches Under Guidance of Ultrasound","volume":"8","author":"Shan","year":"2022","journal-title":"Front. Surg."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1111\/j.1365-2044.2010.06487.x","article-title":"Cardiac Arrest Following Stellate Ganglion Block Performed under Ultrasound Guidance","volume":"65","author":"Rastogi","year":"2010","journal-title":"Anaesthesia"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.2165\/11634970-000000000-00000","article-title":"Opioid-Induced Bowel Dysfunction","volume":"72","author":"Brock","year":"2012","journal-title":"Drugs"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.clineuro.2014.08.036","article-title":"Constipation after Thoraco-Lumbar Fusion Surgery","volume":"126","author":"Stienen","year":"2014","journal-title":"Clin. Neurol. Neurosurg."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S1098-7339(06)80016-7","article-title":"Stellate Ganglion Block Alleviates Pseudo-Obstruction Symptoms Followed by Episodes of Hypermetropia: Case Report","volume":"22","author":"Devulder","year":"1997","journal-title":"Reg. Anesth."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3748\/wjg.v23.i3.533","article-title":"Efficacy and Safety of Stellate Ganglion Block in Chronic Ulcerative Colitis","volume":"23","author":"Zhao","year":"2017","journal-title":"World J. Gastroenterol."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"7628183","DOI":"10.1155\/2022\/7628183","article-title":"Effects of Ultrasound-Guided Stellate Ganglion Block on Postoperative Quality of Recovery in Patients Undergoing Breast Cancer Surgery: A Randomized Controlled Clinical Trial","volume":"2022","author":"Yang","year":"2022","journal-title":"J. Healthc. Eng."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.dld.2020.11.028","article-title":"Ultrasound-Guided Stellate Ganglion Block Alleviates Stress Responses and Promotes Recovery of Gastrointestinal Function in Patients","volume":"53","author":"Zhu","year":"2021","journal-title":"Dig. Liver Dis."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1016\/j.clinthera.2017.09.008","article-title":"Ultrasound-Guided Stellate Ganglion Block Improves Gastrointestinal Function After Thoracolumbar Spinal Surgery","volume":"39","author":"Peng","year":"2017","journal-title":"Clin. Ther."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1213\/ANE.0b013e3181f1d48f","article-title":"Ultrasound-Guided Deep or Intermediate Cervical Plexus Block: The Target Should Be the Posterior Cervical Space","volume":"111","author":"Choquet","year":"2010","journal-title":"Anesth. 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