{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:46:53Z","timestamp":1793112413606,"version":"4.5.0"},"reference-count":73,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: Evidence suggests increased anxious-depressive symptoms in the general population during the COVID-19 pandemic, also in its second wave. High symptom variability across individuals suggests that risk and protective factors, including coping strategies, can play a mediating role. Methods: General Anxiety Disorder-7, Patient Health Questionnaire-9, and Brief-COPE questionnaires were administered to people attending a COVID-19 point-of-care. Univariate and multivariate methods were used to test the association of symptoms with risk and protective factors. Results: A total of 3509 participants (27.5% with moderate-severe anxiety; 12% with depressive symptoms) were recruited. Sociodemographic and lifestyle factors, including age, sex, sleep, physical activity, psychiatric treatments, parenthood, employment, and religiosity were associated with affective symptoms. Avoidant (self-distraction, venting, behavioral disengagement) and approach (emotional support, self-blame but not positive reframing and acceptance) coping strategies predicted greater anxiety. Avoidant strategies, including venting, denial, behavioral disengagement, substance use, and self-blame, and the humor strategy were associated with more severe depressive symptoms, while the planning predicted the opposite. Conclusions: Coping strategies, in addition to socio-demographic and life-habit factors, could have contributed to modulating anxious and depressive symptoms during the second-wave of the COVID-19 pandemic, thus advocating for interventions aimed at promoting positive coping strategies to reduce the psychosocial toll of the pandemic.<\/jats:p>","DOI":"10.3390\/ijerph20042974","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T05:37:31Z","timestamp":1675834651000},"page":"2974","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Anxiety and Depression during the Second Wave of the COVID-19 Pandemic: The Role of Coping Strategies"],"prefix":"10.3390","volume":"20","author":[{"given":"Alessandro","family":"Miola","sequence":"first","affiliation":[{"name":"Department of Neuroscience (DNS), Padua Neuroscience Center, University of Padova, 35127 Padua, Italy"},{"name":"Medicine Faculty, University of Padova, 35127 Padua, Italy"},{"name":"Casa di Cura Parco dei Tigli, 35037 Teolo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Caiolo","sequence":"additional","affiliation":[{"name":"Medicine Faculty, University of Padova, 35127 Padua, Italy"},{"name":"Psychiatry Section, Military Department of Forensic Medicine, 35137 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1948-6971","authenticated-orcid":false,"given":"Giancarlo","family":"Pontoni","sequence":"additional","affiliation":[{"name":"Psychiatry Section, Psychophysiological Selection Office, Italian Army National Recruitment and Selection Center, 06034 Foligno, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Pozzan","sequence":"additional","affiliation":[{"name":"Medicine Faculty, University of Padova, 35127 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Moriglia","sequence":"additional","affiliation":[{"name":"Psyops Development Center, 28th (APICE) Regiment \u201cPavia\u201d, 61121 Pesaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Simionato","sequence":"additional","affiliation":[{"name":"Medicine Faculty, University of Padova, 35127 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Garofalo","sequence":"additional","affiliation":[{"name":"Psychiatry Section, Military Department of Forensic Medicine, 35137 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Perini","sequence":"additional","affiliation":[{"name":"Department of Neuroscience (DNS), Padua Neuroscience Center, University of Padova, 35127 Padua, Italy"},{"name":"Medicine Faculty, University of Padova, 35127 Padua, Italy"},{"name":"Casa di Cura Parco dei Tigli, 35037 Teolo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2102-416X","authenticated-orcid":false,"given":"Fabio","family":"Sambataro","sequence":"additional","affiliation":[{"name":"Department of Neuroscience (DNS), Padua Neuroscience Center, University of Padova, 35127 Padua, Italy"},{"name":"Medicine Faculty, University of Padova, 35127 Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Bonati, M., Campi, R., Zanetti, M., Cartabia, M., Scarpellini, F., Clavenna, A., and Segre, G. 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