{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:44:15Z","timestamp":1770749055241,"version":"3.50.0"},"reference-count":54,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T00:00:00Z","timestamp":1676592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Thematic Excellence Program 2021 Health Sub-program of the Ministry for Innovation and Technology in Hungary","award":["EGA-10"],"award-info":[{"award-number":["EGA-10"]}]},{"name":"Thematic Excellence Program 2021 Health Sub-program of the Ministry for Innovation and Technology in Hungary","award":["RRF-2.3.1-21-2022-00012"],"award-info":[{"award-number":["RRF-2.3.1-21-2022-00012"]}]},{"name":"National Laboratory on Human Reproduction","award":["EGA-10"],"award-info":[{"award-number":["EGA-10"]}]},{"name":"National Laboratory on Human Reproduction","award":["RRF-2.3.1-21-2022-00012"],"award-info":[{"award-number":["RRF-2.3.1-21-2022-00012"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Peripheral artery disease (PAD) is a progressive atherosclerotic disease significantly impacting functional status and health-related quality of life (HRQoL). This study aimed to investigate HRQoL among PAD patients in Hungary using the validated Hungarian version of the PADQoL questionnaire. Patients with symptomatic PAD were consecutively recruited from the Department of Angiology, Clinical Center, University of P\u00e9cs, Hungary. Demographics, risk factors, and comorbidities were registered. Disease severity was measured by Fontaine and WIFI stages. Descriptive statistical analysis, Chi-square test, and non-parametric tests were performed (p &lt; 0.05). Overall, 129 patients (mean age 67.6 \u00b1 11.9 years, men 51.9%) participated in our study. The Hungarian PADQoL demonstrated good internal consistency (\u03b1 range: 0.745\u20130.910). Factors on intimate and social relationships gave the best (89.15 \u00b1 20.91; 63.17 \u00b1 26.05) and sexual function (28.64 \u00b1 27.42), and limitations in physical functioning (24.68 \u00b1 11.40) the worst scores. PAD had a significant negative impact on the social relationships of patients aged 21\u201354 years (51.6 \u00b1 25.4). Fontaine stage IV patients experienced significantly lower HRQoL due to fear and uncertainty (46.3 \u00b1 20.9) and limited physical functioning (33.2 \u00b1 24.8). The Hungarian PADQoL identified central aspects of HRQoL. Advanced PAD was found to impact several areas of HRQoL, primarily physical functioning and psycho-social well-being, drawing attention to the importance of early diagnosis and management.<\/jats:p>","DOI":"10.3390\/ijerph20043558","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T02:27:24Z","timestamp":1676600844000},"page":"3558","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Disease-Specific Quality of Life among Patients with Peripheral Artery Disease in Hungary"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2744-0669","authenticated-orcid":false,"given":"Lilla","family":"Horv\u00e1th","sequence":"first","affiliation":[{"name":"Centre for Occupational Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imre","family":"Boncz","sequence":"additional","affiliation":[{"name":"Institute for Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 7621 P\u00e9cs, Hungary"},{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3698-8466","authenticated-orcid":false,"given":"Zsuzsanna","family":"K\u00edv\u00e9s","sequence":"additional","affiliation":[{"name":"Institute for Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 7621 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gergely","family":"Feh\u00e9r","sequence":"additional","affiliation":[{"name":"Department of Primary Health Care, University of P\u00e9cs, 7623 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"No\u00e9mi","family":"N\u00e9meth","sequence":"additional","affiliation":[{"name":"Institute for Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 7621 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanni Luca","family":"Kajos","sequence":"additional","affiliation":[{"name":"Institute for Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 7621 P\u00e9cs, Hungary"},{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Bir\u00f3","sequence":"additional","affiliation":[{"name":"1st Department of Internal Medicine, Medical School, Clinical Center, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krisztina","family":"Fendrik","sequence":"additional","affiliation":[{"name":"1st Department of Internal Medicine, Medical School, Clinical Center, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Koltai","sequence":"additional","affiliation":[{"name":"1st Department of Internal Medicine, Medical School, Clinical Center, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"K\u00e9sm\u00e1rky","sequence":"additional","affiliation":[{"name":"1st Department of Internal Medicine, Medical School, Clinical Center, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8979-1686","authenticated-orcid":false,"given":"D\u00f3ra","family":"Endrei","sequence":"additional","affiliation":[{"name":"Institute for Health Insurance, Faculty of Health Sciences, University of P\u00e9cs, 7621 P\u00e9cs, Hungary"},{"name":"1st Department of Internal Medicine, Medical School, Clinical Center, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.gheart.2013.12.008","article-title":"Global and Regional Burden of Death and Disability From Peripheral Artery Disease, 21 World Regions, 1990 to 2010","volume":"9","author":"Sampson","year":"2014","journal-title":"Global. Heart"},{"key":"ref_2","unstructured":"GBD 2016 Disease and Injury Incidence and Prevalence Collaborators (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990\u20132016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390, 1211\u20131259."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1161\/hc4601.099487","article-title":"Global Burden of Cardiovascular Diseases Part I: General considerations, the Epidemiologic Transition, Risk Factors, and Impact of Urbanisation","volume":"104","author":"Yusuf","year":"2001","journal-title":"Circulation"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(13)61249-0","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: A systematic review and analysis","volume":"382","author":"Fowkes","year":"2013","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/1358863X9700200310","article-title":"The epidemiology of peripheral arterial disease: Importance of identifying the population at risk","volume":"2","author":"Criqui","year":"1997","journal-title":"Vasc. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/1358863X9300400102","article-title":"The Epidemiology of peripheral arterial disease","volume":"4","author":"Leng","year":"1993","journal-title":"Vasc. Med. Rev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1161\/01.ATV.18.2.185","article-title":"Peripheral arterial disease in the elderly: The Rotterdam Study","volume":"18","author":"Meijer","year":"1998","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1093\/ije\/25.2.282","article-title":"The Prevalence of Asymptomatic and Unrecognised Peripheral Arterial Occlusive Disease","volume":"25","author":"Stoffers","year":"1996","journal-title":"Int. J. Epidemiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1177\/1358863X08089277","article-title":"National health care costs of peripheral artery disease in the Medicare population","volume":"13","author":"Hirsch","year":"2008","journal-title":"Vasc. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1177\/1358863X16631041","article-title":"Administrative data are not sensitive enough for the detection of peripheral artery disease in the community","volume":"21","author":"Hong","year":"2016","journal-title":"Vasc. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0140-6736(06)69369-0","article-title":"Financial deficits in the health services of the UK and Hungary","volume":"368","author":"Boncz","year":"2006","journal-title":"Lancet"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jval.2014.01.011","article-title":"Multicriteria Decision Analysis in the Reimbursement of New Medical Technologies: Real-World Experiences from Hungary","volume":"17","author":"Endrei","year":"2014","journal-title":"Value. Health"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/eurheartj\/ehx095","article-title":"2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)","volume":"39","author":"Aboyans","year":"2017","journal-title":"Eur. Heart J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1177\/1358863X13480001","article-title":"Methods of symptom evaluation and their impact on peripheral artery disease (PAD) symptom prevalence: A review","volume":"18","author":"Schorr","year":"2013","journal-title":"Vasc. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/oxfordjournals.aje.a116294","article-title":"Smoking, lipids, glucose intolerance, and blood pressure as risk factors for peripheral atherosclerosis compared with ischemic heart disease in the Edinburgh Artery Study","volume":"135","author":"Fowkes","year":"1992","journal-title":"Am. J. Epidemiol."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Piotrowska, R., M\u0229drzycka-D\u0105browska, W., Jarzynkowski, P., and Slusarz, R. (2022). Nicotine Dependence and the Level of Motivation for Ceasing Smoking in the Case of Patients Undergoing Vascular Surgeries Versus the Optimisation of Perioperative Care\u2014Pilot Survey. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph191610393"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Achim, A., Stanek, A., Homorodean, C., Spinu, M., Onea, H.L., Laz\u0103r, L., Marc, M., Ruzsa, Z., and Olinic, D.M. (2022). Approaches to Peripheral Artery Disease in Diabetes: Are There Any Differences?. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19169801"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2147\/VHRM.S209241","article-title":"The burden of critical limb ischaemia: Review of recent literature","volume":"15","author":"Duff","year":"2019","journal-title":"Vasc. Health. Risk. Man."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/eurheartj\/ehv006","article-title":"Peripheral arterial disease and critical limb ischaemia: Still poor outcomes and lack of guideline adherence","volume":"36","author":"Reinecke","year":"2015","journal-title":"Eur. Heart J."},{"key":"ref_20","first-page":"24","article-title":"The impact of peripheral artery disease on quality of life. [A perif\u00e9ri\u00e1s ver\u0151\u00e9rbetegs\u00e9g hat\u00e1sa az \u00e9letmin\u0151s\u00e9gre]","volume":"18","author":"Brodszky","year":"2011","journal-title":"\u00c9rbetegs\u00e9gek"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Kim, M., Kim, Y., Ryu, G.W., and Choi, M. (2021). Functional Status and Health-Related Quality of Life in Patients with Peripheral Artery Disease: A Cross-Sectional Study. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph182010941"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Hassan, E.B., Phu, S., Warburton, E., Humaith, N., and Wijeratne, T. (2021). Frailty in Stroke-A Narrated Review. Life, 11.","DOI":"10.3390\/life11090891"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1046\/j.1525-1497.2003.20527.x","article-title":"Depressive Symptoms and Lower Extremity Functioning in Men and Women with Peripheral Arterial Disease","volume":"18","author":"Greenland","year":"2003","journal-title":"J. Gen. Intern. Med."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"T\u00f3th-Vajna, G., T\u00f3th-Vajna, Z., Balog, P., and Konkoly Thege, B. (2020). Depressive symptomatology and personality traits in patients with symptomatic and asymptomatic peipheral arterial disease. BMC Cardiovasc. Disord., 20.","DOI":"10.1186\/s12872-020-01586-y"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"109963","DOI":"10.1016\/j.jpsychores.2020.109963","article-title":"Mental health concerns in patients with symptomatic peripheral artery disease: Insights from the PORTRAIT registry","volume":"131","author":"Thomas","year":"2020","journal-title":"J. Psychosom. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ejvs.2018.04.017","article-title":"International Variations in Amputation Practice: A VASCUNET Report","volume":"56","author":"Behrendt","year":"2018","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.ejvs.2019.10.021","article-title":"Lower Limb Amputations and Revascularisation Procedures in the Hungarian Population; A 14 Year Retrospective Cohort Study","volume":"59","author":"Ferenci","year":"2020","journal-title":"Eur. J. Vasc. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/028134398750003142","article-title":"Risk factors and cardiovascular diseases associated with asymptomatic peripheral artery occlusive disease: The Limburg PAOD study","volume":"16","author":"Hooi","year":"1998","journal-title":"Scan. J. Prim. Health Care."},{"key":"ref_29","first-page":"1381","article-title":"A summary of data of screening of the lower limb peripheral arterial diseases in the region of Northern Hungary. (Tapasztalataink az als\u00f3 v\u00e9gtagi perif\u00e9ri\u00e1s art\u00e9ri\u00e1s \u00e9rbetegs\u00e9g sz\u0171r\u00e9s\u00e9r\u0151l az \u00c9szak-Magyarorsz\u00e1gi r\u00e9gi\u00f3ban.)","volume":"161","author":"Gombos","year":"2020","journal-title":"Orv. Hetil."},{"key":"ref_30","unstructured":"Cigan, V., Kraki\u0107, A.-M., and Omr\u010den, D. (2019, January 21\u201323). Translation Challenges During the Linguistic Validation of PADQoL (Peripheral Artery Disease Quality of Life) Questionnaire into Hungarian. Proceedings of the IV International Conference from Theory to Practice in Language For Specific Purposes, Zagreb, Croatia."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1024\/0301-1526\/a000845","article-title":"Simple assessment of quality of life and lower limb functional capacity during cilostazol treatment\u2014Results of the SHOrt-tERm cIlostazol eFFicacy and quality of life (SHERIFF) study","volume":"49","author":"Farkas","year":"2020","journal-title":"Vasa"},{"key":"ref_32","first-page":"28","article-title":"The significance of measuring quality of life in peripheral artery disease. (Az \u00e9letmin\u0151s\u00e9g m\u00e9r\u00e9s\u00e9nek jelent\u0151s\u00e9ge perif\u00e9ri\u00e1s ver\u0151\u00e9rbetegs\u00e9gben)","volume":"18","author":"Brodszky","year":"2011","journal-title":"\u00c9rbetegs\u00e9gek"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jvs.2004.11.022","article-title":"Comparison of generic and disease-specific questionnaires for the assessment of quality of life in patients with peripheral artery disease","volume":"41","author":"Ouwendijk","year":"2005","journal-title":"J. Vasc. Surg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1177\/1358863X12466708","article-title":"The PADQoL: Development and Validation of a PAD-specific quality of life questionnaire","volume":"17","author":"Lindquist","year":"2012","journal-title":"Vasc. Med."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1524-4733.2005.04054.x","article-title":"Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient-Reported Outcomes (PRO) Measures: Report of the ISPOR Task Force for Translation and Cultural Adaptation","volume":"8","author":"Wild","year":"2005","journal-title":"Value. Health"},{"key":"ref_36","first-page":"9","article-title":"Enhancing Cross-Cultural Appropriateness for Newly Developed Patient-Reported Outcome (PRO) Instruments: The Use of Translatability Assessment","volume":"44","author":"Conway","year":"2010","journal-title":"Pro Newsl."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1097\/00007632-200012150-00014","article-title":"Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures","volume":"25","author":"Beaton","year":"2000","journal-title":"Spine"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"S567","DOI":"10.1016\/j.jval.2019.09.862","article-title":"Cross-Cultural Adaptation and Validation of the Peripheral Artery Disease Quality of Life (PADQoL) Questionnaire into Hungarian: Piloting Results","volume":"22","author":"Boncz","year":"2019","journal-title":"Value Health"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1556\/650.2020.31920","article-title":"Hungarian Adaptation of the Peripheral Artery Disease Quality of Life Questionnaire. (A perif\u00e9ri\u00e1s \u00e9rbetegek \u00e9letmin\u0151s\u00e9g\u00e9t vizsg\u00e1l\u00f3 angol nyelv\u0171 k\u00e9rd\u0151\u00edv Magyar adapt\u00e1l\u00e1sa)","volume":"161","author":"Boncz","year":"2020","journal-title":"Orv. Hetil."},{"key":"ref_40","first-page":"499","article-title":"Surgical Treatment of peripheral circulation disorders","volume":"21","author":"Fontaine","year":"1954","journal-title":"Helv. Chir. Acta."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jvs.2013.08.003","article-title":"The society for vascular surgery lower extremity threatened limb classification system: Risk stratification based on Wound, Ischaemia, and foot Infection (WIFI)","volume":"59","author":"Mills","year":"2014","journal-title":"J. Vasc. Surg."},{"key":"ref_42","first-page":"1","article-title":"WIFI classification: The Society for Vascular Surgery lower extremity threatened limb classification system, a literature review","volume":"19","author":"Cerqueira","year":"2020","journal-title":"J. Vasc. Bras."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1161\/STROKEAHA.118.023534","article-title":"Stroke in Patients with Peripheral Artery Disease","volume":"50","author":"Kolls","year":"2019","journal-title":"Stroke"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s10198-014-0602-8","article-title":"Changes in the health status of the population of Central and Eastern European countries between 1990 and 2010","volume":"15","author":"Boncz","year":"2014","journal-title":"Eur. J. Health Econ."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Anghel, R., Adam, C.A., Marcu, D.T.M., Mitu, O., Roca, M., Tinica, G., and Mitu, F. (2022). Cardiac Rehabilitation in Peripheral Artery Disease in a Tertiary Center-Impact on Arterial Stiffness and Functional Status after 6 Months. Life, 12.","DOI":"10.3390\/life12040601"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1556\/oh.2010.28817","article-title":"Epidemiology of smoking in Hungary\u2014A representative national study","volume":"151","author":"Tombor","year":"2010","journal-title":"Orv. Hetil."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1001\/jama.2018.8357","article-title":"Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle-Brachial Index, US Preventive Services Task Force Recommendation Statement","volume":"320","author":"Curry","year":"2018","journal-title":"JAMA"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Horv\u00e1th, L., N\u00e9meth, N., Feh\u00e9r, G., K\u00edv\u00e9s, Z., Endrei, D., and Boncz, I. (2022). The Epidemiology of Peripheral Artery Disease: Narrative Review. Life, 12.","DOI":"10.3390\/life12071041"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ejvs.2015.02.019","article-title":"Trends in major lower limb amputation related to peripheral arterial disease in Hungary: A Nationwide Study (2004-2012)","volume":"50","author":"Ferenci","year":"2015","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1177\/1538574420952923","article-title":"Erectile Dysfunction in Peripheral Vascular Disease: Endovascular Revascularisation as a Potential Therapeutic Target","volume":"54","author":"Benarargama","year":"2020","journal-title":"Vasc. Endovasc. Surg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.atherosclerosis.2021.04.020","article-title":"Psychosocial factors and subsequent risk of hospitalisations with peripheral artery disease: The Atherosclerotic Risk in communities [ARIC] Study","volume":"329","author":"Honda","year":"2021","journal-title":"Atheroclerosis"},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Abaraogu, U.O., Ezenwankwo, E.F., Dall, P., and Seenan, C.A. (2018). Living a burdensome and demanding life: A qualitative systematic review of the patients experiences of peripheral arterial disease. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0207456"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/1358863X07084911","article-title":"The impact of peripheral arterial disease on health-related quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) Program","volume":"13","author":"Regensteiner","year":"2008","journal-title":"Vasc. Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e013538","DOI":"10.1161\/JAHA.119.013538","article-title":"Job Strain as a Risk Factor for Peripheral Artery Disease: A Multi-Cohort Study","volume":"9","author":"Pentti","year":"2020","journal-title":"JAHA"}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/4\/3558\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:39:06Z","timestamp":1760121546000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/4\/3558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,17]]},"references-count":54,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["ijerph20043558"],"URL":"https:\/\/doi.org\/10.3390\/ijerph20043558","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,17]]}}}