{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T10:42:43Z","timestamp":1763116963179,"version":"build-2065373602"},"reference-count":8,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Background: The aim of this study was to assess the RV (right ventricle) and LV (left ventricle) Tei index in large for gestational age (LGA) fetuses with a single 360-degree umbilical coil of the umbilical cord around the fetal neck identified by ultrasound in the third trimester of gestation. (2) Methods: The RV and LV Tei index for the cardiac function were measured in 297 singleton pregnancies, and we identified 25 LGA fetuses. There were 48% of LGA fetuses with a nuchal umbilical cord\u2014LGA\/NC\u2014larger for gestational age fetuses with a nuchal cord. NC was detected with a color Doppler during a transverse scan of the fetal neck, when the umbilical cord formed a U shape. All fetuses had normal anatomy and normal uterine, placental, umbilical, intracardiac and cerebral Doppler waveforms values for their gestational age. (3) Results: The RV Tei index was significantly higher in the LGA subgroup vs. AGA (0.6 \u00b1 0.2 vs. 0.50 \u00b1 0.2; p value = 0.01), but in LGA fetuses with a single coil of the nuchal cord, there were not any significant changes in the Tei indexes. (4) Conclusions: The Tei index might not be impacted by the presence of the nuchal cord in LGA fetuses.<\/jats:p>","DOI":"10.3390\/ijerph20053778","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T02:07:44Z","timestamp":1676945264000},"page":"3778","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Presence of a Single Nuchal Cord in the Third Trimester May Not Affect Tei Index in LGA Fetuses"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8266-4585","authenticated-orcid":false,"given":"Julia","family":"Murlewska","sequence":"first","affiliation":[{"name":"Department of Prenatal Cardiology, Polish Mother\u2019s Memorial Hospital Research Institute, 93-338 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6004-5401","authenticated-orcid":false,"given":"Przemys\u0142aw","family":"Poszwa","sequence":"additional","affiliation":[{"name":"Institute of Materials Technology, Poznan University of Technology, 61-138 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oskar","family":"Sylwestrzak","sequence":"additional","affiliation":[{"name":"Department of Prenatal Cardiology, Polish Mother\u2019s Memorial Hospital Research Institute, 93-338 Lodz, Poland"},{"name":"Department of Diagnoses and Prevention Fetal Malformations, Medical University of Lodz, 90-419 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0238-2172","authenticated-orcid":false,"given":"Maria","family":"Respondek-Liberska","sequence":"additional","affiliation":[{"name":"Department of Prenatal Cardiology, Polish Mother\u2019s Memorial Hospital Research Institute, 93-338 Lodz, Poland"},{"name":"Department of Diagnoses and Prevention Fetal Malformations, Medical University of Lodz, 90-419 Lodz, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis","family":"Wood","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40748-017-0068-7","article-title":"Nuchal cord and its implications","volume":"3","author":"Peesay","year":"2017","journal-title":"Matern. Health Neonatol. Perinatol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1515\/jpm-2020-0316","article-title":"The effect of nuchal umbilical cord on fetal cardiac and cerebral circulation-cross-sectional study","volume":"49","author":"Murlewska","year":"2021","journal-title":"J. Perinat. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/uog.1959","article-title":"A modified myocardial performance (Tei) index based on the use of valve clics improves reproducibility of fetal left cardiac function assessment","volume":"26","author":"Carreras","year":"2005","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/uog.3947","article-title":"Gestational-age-adjusted reference values for the modified myocardial performance index for evaluation of fetal left cardiac function","volume":"29","author":"Kottman","year":"2007","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_5","unstructured":"McKinney, W. (July, January 28). Data Structures for Statistical Computing in Python. Proceedings of the 9th Python in Science Conference, Austin, TX, USA."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Virtanen, P., Gommers, R., Oliphant, T.E., Haberland, M., Reddy, T., Cournapeau, D., Burovski, E., Peterson, P., Weckesser, W., and Bright, J. (2020). SciPy 1.0: Fundamental Algorithms for Scientific Computing in Python. Nat. Methods, in press.","DOI":"10.1038\/s41592-020-0772-5"},{"key":"ref_7","first-page":"2927","article-title":"Assessments of M-mode color echocardiography on fetal right ventricular diastolic function with umbilical cord around neck","volume":"21","author":"Shi","year":"2017","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1002\/uog.1874","article-title":"Is fetal cerebral vascular resistance affected by the presence of nuchal cord(s) in the third trimester of pregnancy?","volume":"25","author":"Sherer","year":"2005","journal-title":"Ultrasound Obstet. Gynecol."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/5\/3778\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:37:51Z","timestamp":1760121471000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/5\/3778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,21]]},"references-count":8,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["ijerph20053778"],"URL":"https:\/\/doi.org\/10.3390\/ijerph20053778","relation":{},"ISSN":["1660-4601"],"issn-type":[{"type":"electronic","value":"1660-4601"}],"subject":[],"published":{"date-parts":[[2023,2,21]]}}}