{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:27:54Z","timestamp":1787840874902,"version":"build-2784847793"},"reference-count":41,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Intensive rehabilitation programs improve motor and non-motor symptoms in people with Parkinson\u2019s disease (PD), however, it is not known whether transfer to daily-living walking occurs. The effects of multidisciplinary-intensive-outpatient rehabilitation (MIOR) on gait and balance in the clinic and on everyday walking were examined. Forty-six (46) people with PD were evaluated before and after the intensive program. A 3D accelerometer placed on the lower back measured daily-living walking during the week before and after the intervention. Participants were also stratified into \u201cresponders\u201d and \u201cnon-responders\u201d based on daily-living-step-counts. After the intervention, gait and balance significantly improved, e.g., MiniBest scores (p &lt; 0.001), dual-task gait speed increased (p = 0.016) and 6-minute walk distance increased (p &lt; 0.001). Many improvements persisted after 3 months. In contrast, daily-living number of steps and gait quality features did not change in response to the intervention (p &gt; 0.1). Only among the \u201cresponders\u201d, a significant increase in daily-living number of steps was found (p &lt; 0.001). These findings demonstrate that in people with PD improvements in the clinic do not necessarily carry over to daily-living walking. In a select group of people with PD, it is possible to ameliorate daily-living walking quality, potentially also reducing fall risk. Nevertheless, we speculate that self-management in people with PD is relatively poor; therefore, to maintain health and everyday walking abilities, actions such as long-term engaging in physical activity and preserving mobility may be needed.<\/jats:p>","DOI":"10.3390\/ijerph20053806","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T02:57:38Z","timestamp":1677034658000},"page":"3806","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Multidisciplinary Intensive Rehabilitation Program for People with Parkinson\u2019s Disease: Gaps between the Clinic and Real-World Mobility"],"prefix":"10.3390","volume":"20","author":[{"given":"Moriya","family":"Cohen","sequence":"first","affiliation":[{"name":"Center for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv 6492416, Israel"},{"name":"Ezra Lemarpeh Center, Bnei Brak 5111501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talia","family":"Herman","sequence":"additional","affiliation":[{"name":"Center for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv 6492416, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Ganz","sequence":"additional","affiliation":[{"name":"Center for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv 6492416, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inbal","family":"Badichi","sequence":"additional","affiliation":[{"name":"Ezra Lemarpeh Center, Bnei Brak 5111501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Gurevich","sequence":"additional","affiliation":[{"name":"Movement Disorders Unit, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv 6492416, Israel"},{"name":"Sagol School of Neuroscience, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel"},{"name":"Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1608-0776","authenticated-orcid":false,"given":"Jeffrey M.","family":"Hausdorff","sequence":"additional","affiliation":[{"name":"Center for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv 6492416, Israel"},{"name":"Sagol School of Neuroscience, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel"},{"name":"Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel"},{"name":"Rush Alzheimer\u2019s Disease Center and Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/1545968314542981","article-title":"Intensive rehabilitation treatment in early Parkinson\u2019s disease: A randomized pilot study with a 2-year follow-up","volume":"29","author":"Frazzitta","year":"2015","journal-title":"Neurorehabil. 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