{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:46:06Z","timestamp":1787028366080,"version":"build-2736575974"},"reference-count":42,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>The use of autogenic drainage (AD) in patients with cystic fibrosis (CF) has been officially approved; therefore, the purpose of this study was to compare the efficiency of the leading therapeutic techniques based on AD in patients with CF; Among patients with CF assessments were made of spirometric parameters, percent blood oxygen saturation, and the general feeling of the patients (Borg, VAS, and mMRC dyspnea scale) before and after therapy using AD, using AD in connection with a belt or a Simeox device and AD in combination with both a belt and Simeox device simultaneously. The best therapeutic effects were generated by the combination of AD with the belt and with the Simeox device. The greatest improvements were observed for FEV1, FVC, PEF, FET, saturation, and patient comfort. In patients &lt;10.5 years of age, the increase in the level of FEV3 and FEV6 was significant in comparison to older patients. Due to their efficacy, therapies connected with AD should be applied not only in hospital departments but also during daily patient care. Given the particular benefits observed in patients &lt;10.5 years of age, it is important to guarantee real accessibility to this form of physiotherapy, especially in this age group.<\/jats:p>","DOI":"10.3390\/ijerph20053822","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T02:57:38Z","timestamp":1677034658000},"page":"3822","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of Autogenic Drainage in Improving Pulmonary Function in Patients with Cystic Fibrosis"],"prefix":"10.3390","volume":"20","author":[{"given":"Magdalena","family":"\u017bak","sequence":"first","affiliation":[{"name":"Physiotherapist\u2019s Office Children\u2019s Therapy in Szczecin, 71-502 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugues","family":"Gauchez","sequence":"additional","affiliation":[{"name":"Centre de Kin\u00e9sith\u00e9rapie Respiratoire et Fonctionnelle du Nord in Marcq en Baroeul, 59700 Marcq-en-Bar\u0153ul, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Boberski","sequence":"additional","affiliation":[{"name":"Institute of Respiratory and Neurodevelopmental Support for Children in Szczecin, 71-502 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Stangret","sequence":"additional","affiliation":[{"name":"Department of Medical Biology, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7513-8640","authenticated-orcid":false,"given":"Agnieszka","family":"Kempinska-Podhorodecka","sequence":"additional","affiliation":[{"name":"Department of Medical Biology, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jcf.2014.03.009","article-title":"European Cystic Fibrosis Society Standards of Care: Framework for the Cystic Fibrosis Centre","volume":"13","author":"Conway","year":"2014","journal-title":"J. Cyst. Fibros."},{"key":"ref_2","unstructured":"Chevaillier, J. (2016). Autogenic Drainage: The Flow and Breathing Level Modulation Concept, Servei de Publicacions de la Universitat Aut\u00f2noma de Barcelona."},{"key":"ref_3","first-page":"11","article-title":"Recommandations des journ\u00e9es internationales de kin\u00e9sith\u00e9rapie respiratoire instrumentale (JIKRI)","volume":"209","author":"Barthe","year":"2001","journal-title":"Cah. De Kin\u00e9sith\u00e9rapie"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.rmr.2015.12.004","article-title":"Manual airway clearance techniques in adults and adolescents: What level of evidence?","volume":"35","author":"Cabillic","year":"2018","journal-title":"Rev. Mal. Respir."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/resp.12764","article-title":"Physiotherapy for cystic fibrosis in Australia and New Zealand: A clinical practice guideline","volume":"21","author":"Button","year":"2016","journal-title":"Respirology"},{"key":"ref_6","first-page":"CD009595","article-title":"Autogenic drainage for airway clearance in cystic fibrosis","volume":"10","author":"McCormack","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_7","unstructured":"Miossec, M. (2021, September 27). Drainage Autog\u00e8ne (DA) versus Expiration Lente et Totale Glotte Ouverte (ELTGOL) pour le D\u00e9sencombrement Bronchique des Patients Atteints de Mucoviscidose. Available online: https:\/\/dumas.ccsd.cnrs.fr\/dumas-01739642\/document."},{"key":"ref_8","unstructured":"Chevaillier, J. (2021, September 28). Autogenic Drainage (AD) \u201cThe Concept of Flow and Breathing Level Modulation\u201d. Physiotherapy for People with Cystic Fibrosis: From Infant to Adult. Available online: https:\/\/www.ecfs.eu\/sites\/default\/files\/general-content-files\/working-groups\/IPG%20CF_Blue%20Booklet_7th%20edition%202019.pdf."},{"key":"ref_9","first-page":"23","article-title":"A systematic Cochrane Review of autogenic drainage (AD) for airway clearance in cystic fibrosis","volume":"29","author":"McCormack","year":"2019","journal-title":"Paediatr. Respir. Rev."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1002\/ppul.21247","article-title":"Long-Term Comparative Trial of Two Different Physiotherapy Techniques; Postural Drainage with Percussion and Autogenic Drainage, in the treatment of Cystic Fibrosis","volume":"45","author":"McIlwaine","year":"2010","journal-title":"Pediatr. Pulmonol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1378\/chest.114.1.171","article-title":"Sputum rheology changes in cystic fibrosis lung disease following two different types of physiotherapy\u2014Flutter vs autogenic drainage","volume":"114","author":"App","year":"1998","journal-title":"Chest"},{"key":"ref_12","unstructured":"McIlwaine, P., Davidson, A., Wong, L., Pirie, G., and Nakielna, E. (1991, January 18\u201321). In Comparison of positive expiratory pressure and autogenic drainage with conventional percussion and drainage therapy in the treatment of cystic fibrosis. Proceedings of the 17th European Cystic Fibrosis Conference, Copenhagen, Denmark."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1136\/thx.2008.111492","article-title":"Short-term comparative study of high frequency chest wall oscillation and European airway clearance techniques in patients with cystic fibrosis","volume":"65","author":"Osman","year":"2010","journal-title":"Thorax"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1136\/thx.50.2.165","article-title":"Chest physiotherapy in cystic fibrosis: A comparative study of autogenic drainage and the active cycle of breathing techniques with postural drainage","volume":"50","author":"Miller","year":"1995","journal-title":"Thorax"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jcf.2010.01.004","article-title":"Beyond postural drainage and percussion: Airway clearance in people with cystic fibrosis","volume":"9","author":"Pryor","year":"2010","journal-title":"J. Cyst. Fibros."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.4187\/respcare.04008","article-title":"The Short-Term Effect of Breathing Tasks Via an Incentive Spirometer on Lung Function Compared with Autogenic Drainage in Subjects with Cystic Fibrosis","volume":"60","author":"Sokol","year":"2015","journal-title":"Respir. Care"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/BF00177578","article-title":"Self-administered chest physiotherapy in cystic fibrosis: A comparative study of high-pressure PEP and autogenic drainage","volume":"170","author":"Pfleger","year":"1992","journal-title":"Lung"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Wallaert, E., Perez, T., Prevotat, A., Reychler, G., Wallaert, B., and Le Rouzic, O. (2018). The immediate effects of a single autogenic drainage session on ventilatory mechanics in adult subjects with cystic fibrosis. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0195154"},{"key":"ref_19","first-page":"1","article-title":"Application of the SIMEOX airway clearance technology in the treatment of cystic fibrosis pulmonary exacerbation-a case report","volume":"1","author":"Sands","year":"2018","journal-title":"Simeox Clin. Noteb."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/jbm.a.36251","article-title":"Rheological properties of synthetic mucus for airway clearance","volume":"106","author":"Lafforgue","year":"2018","journal-title":"J. Biomed. Mater. Res. A"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"110003","DOI":"10.1063\/1.5016758","article-title":"Rheological Characterization of Macromolecular Colloidal Gels as Simulant of Bronchial Mucus","volume":"1914","author":"Lafforgue","year":"2017","journal-title":"Aip Conf. Proc."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1002\/jbm.a.36161","article-title":"Thermo-physical properties of synthetic mucus for the study of airway clearance","volume":"105","author":"Lafforgue","year":"2017","journal-title":"J. Biomed. Mater. Res. A"},{"key":"ref_23","unstructured":"(2017). MATIO Kwartalnik Fundacji Pomocy Rodzinom i Chorym na Mukowiscydoz\u0119. MATIO, 4, 10\u201314."},{"key":"ref_24","first-page":"283","article-title":"Polish Respiratory Society guidelines for the methodology and interpretation of the 6 minute walk test (6MWT)","volume":"83","author":"Przybylowski","year":"2015","journal-title":"Pneumonol. Alergol. Pol."},{"key":"ref_25","first-page":"790","article-title":"Effect of pre-cooling injection site on pain perception in pediatric dentistry: \u201cA randomized clinical trial\u201d","volume":"10","author":"Ghaderi","year":"2013","journal-title":"Dent. Res. J."},{"key":"ref_26","first-page":"66","article-title":"An Insight to Chronic Obstructive Pulmonary Disorder COPD and its Pharmacotherapy","volume":"1","author":"Abbas","year":"2014","journal-title":"Br. Biomed. Bull."},{"key":"ref_27","first-page":"729","article-title":"The Borg scale is accurate in children and adolescents older than 9 years with cystic fibrosis","volume":"55","author":"Hommerding","year":"2010","journal-title":"Respir. Care"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Moran, C.A., Corso, S.D., Bombig, M.T., Serra, A.J., Pereira, S.A., and Peccin, M.S. (2019). Heart rate agreement between the 20-meter shuttle run test and virtual system in healthy children: A cross-sectional study. BMC Pediatr., 19.","DOI":"10.1186\/s12887-019-1861-4"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.pain.2012.01.006","article-title":"Reliability of the visual analog scale in children with acute pain in the emergency department","volume":"153","author":"Bailey","year":"2012","journal-title":"PAIN\u00ae"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1183\/09031936.05.00035205","article-title":"Interpretative strategies for lung function tests","volume":"26","author":"Pellegrino","year":"2005","journal-title":"Eur. Respir. J."},{"key":"ref_31","first-page":"362","article-title":"Office Spirometry: Indications and Interpretation","volume":"101","author":"Langan","year":"2020","journal-title":"Am. Fam. Physician"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1183\/09031936.00166412","article-title":"Factors associated with FEV1 decline in cystic fibrosis: Analysis of the ECFS Patient Registry","volume":"43","author":"Kerem","year":"2014","journal-title":"Eur. Respir. J."},{"key":"ref_33","unstructured":"(2021, September 27). Cystic Fibrosis Foundation Patient Registry 2019 Annual Data Report Bethesda, Maryland. Available online: https:\/\/www.cff.org\/Research\/Researcher-Resources\/Patient-Registry\/2019-Patient-Registry-Annual-Data-Report.pdf."},{"key":"ref_34","unstructured":"Reynaud-Gaubert, M., Averyanov, A., Kolek, V., Sliwinski, P., Mihaltan, F.D., and Solovic, I. (2021, September 27). Simeox Clinical Notebook. Available online: https:\/\/www.physioassist.com\/wp-content\/uploads\/2019\/07\/clinical_notebook_2_08_web.pdf."},{"key":"ref_35","unstructured":"Sands, D.A. (2018). Mukowiscydoza: Choroba Wielouk\u0142adowa, Termedia sp. z oo."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/ppul.1950150204","article-title":"Pulmonary-Function between 6 and 18 Years of Age","volume":"15","author":"Wang","year":"1993","journal-title":"Pediatr. Pulmonol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1164\/rccm.200705-664OC","article-title":"Cystic fibrosis pulmonary guidelines\u2014Chronic medications for maintenance of lung health","volume":"176","author":"Flume","year":"2007","journal-title":"Am. J. Respir. Crit. Care"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jcf.2012.03.009","article-title":"Risk factors for rate of decline in FEV1 in adults with cystic fibrosis","volume":"11","author":"Konstan","year":"2012","journal-title":"J. Cyst. Fibros."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.jcf.2017.05.011","article-title":"A single bout of maximal exercise improves lung function in patients with cystic fibrosis","volume":"16","author":"Tucker","year":"2017","journal-title":"J. Cyst. Fibros."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"842A","DOI":"10.1378\/chest.1680036","article-title":"FEV3, FEV3\/FVC and 1-FEV3\/FVC in Obstructive Lung Disease","volume":"144","author":"Demir","year":"2013","journal-title":"Chest"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"172","DOI":"10.5603\/ARM.28098","article-title":"Evaluation of some anthropometric and clinical parameters in children with cystic fibrosis","volume":"73","author":"Rubinowicz","year":"2005","journal-title":"Pneumonol. Alergol. Pol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/PEP.0000000000000355","article-title":"Autogenic Drainage in Children with Cystic Fibrosis","volume":"29","author":"Corten","year":"2017","journal-title":"Pediatr. Phys. Ther."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/5\/3822\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:38:15Z","timestamp":1760121495000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/5\/3822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,21]]},"references-count":42,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["ijerph20053822"],"URL":"https:\/\/doi.org\/10.3390\/ijerph20053822","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,21]]}}}