{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T02:22:23Z","timestamp":1769826143846,"version":"3.49.0"},"reference-count":53,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,3,12]],"date-time":"2023-03-12T00:00:00Z","timestamp":1678579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Regional Health Management of the Junta de Castilla y Le\u00f3n","award":["EXP. GRS2020\/A\/19"],"award-info":[{"award-number":["EXP. GRS2020\/A\/19"]}]},{"name":"Regional Health Management of the Junta de Castilla y Le\u00f3n","award":["GRS\/2010\/A\/19"],"award-info":[{"award-number":["GRS\/2010\/A\/19"]}]},{"name":"Regional Health Management of Castilla y Le\u00f3n\u2013Sacyl","award":["EXP. GRS2020\/A\/19"],"award-info":[{"award-number":["EXP. GRS2020\/A\/19"]}]},{"name":"Regional Health Management of Castilla y Le\u00f3n\u2013Sacyl","award":["GRS\/2010\/A\/19"],"award-info":[{"award-number":["GRS\/2010\/A\/19"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Parkinson\u2019s disease (PD) is a chronic, neurodegenerative movement disorder, whose symptoms have a negative impact on quality of life and functionality. Although its main treatment is pharmacological, non-pharmacological aids such as the dynamic elastomeric fabric orthosis (DEFO) merit an evaluation. Our objective is to assess the DEFO in upper limb (UL) functional mobility and in the quality of life of PD patients. A total of 40 patients with PD participated in a randomized controlled crossover study, and were assigned to a control group (CG) and to an experimental group (EG). Both groups used the DEFO for two months, the experimental group the first two months of the study and the control group the last two. Motor variables were measured in the ON and OFF states at the baseline assessment and at two months. Differences from the baseline assessment were observed in some motor items of the Kinesia assessment, such as rest tremor, amplitude, rhythm or alternating movements in the ON and OFF states with and without orthosis. No differences were found in the unified Parkinson\u2019s disease rating scale (UPDRS) or the PD quality-of-life questionnaire. The DEFO improves some motor aspects of the UL in PD patients but this does not translate to the amelioration of the standard of functional and quality-of-life scales.<\/jats:p>","DOI":"10.3390\/ijerph20064995","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T04:35:41Z","timestamp":1678682141000},"page":"4995","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Functionality and Quality of Life with Parkinson\u2019s Disease after Use of a Dynamic Upper Limb Orthosis: A Pilot Study"],"prefix":"10.3390","volume":"20","author":[{"given":"Mar\u00eda","family":"Jim\u00e9nez-Barrios","sequence":"first","affiliation":[{"name":"Department of Health Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7298-9060","authenticated-orcid":false,"given":"Jer\u00f3nimo","family":"Gonz\u00e1lez-Bernal","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Cubo","sequence":"additional","affiliation":[{"name":"Neurology Service, Burgos University Hospital, 09006 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Gabriel-Gal\u00e1n","sequence":"additional","affiliation":[{"name":"Neurology Service, Burgos University Hospital, 09006 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1364-2603","authenticated-orcid":false,"given":"Beatriz","family":"Garc\u00eda-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Neurophysiology Service, Burgos University Hospital, 09006 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0670-5303","authenticated-orcid":false,"given":"Anna","family":"Berardi","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences, University of la Sapienza, 00188 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2071-4513","authenticated-orcid":false,"given":"Marco","family":"Tofani","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences, University of la Sapienza, 00188 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9043-5686","authenticated-orcid":false,"given":"Giovanni","family":"Galeoto","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences, University of la Sapienza, 00188 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2251-9095","authenticated-orcid":false,"given":"Martin J. A.","family":"Matthews","sequence":"additional","affiliation":[{"name":"Faculty of Health, School of Health Professions Peninsula Allied Health Centre, University of Plymouth, Derriford Rd., Plymouth PL6 8BH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4255-7355","authenticated-orcid":false,"given":"Mirian","family":"Santamar\u00eda-Pel\u00e1ez","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josefa","family":"Gonz\u00e1lez-Santos","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.3233\/JPD-181474","article-title":"The Emerging Evidence of the Parkinson Pandemic","volume":"8","author":"Dorsey","year":"2018","journal-title":"J. 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