{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:14:45Z","timestamp":1791587685440,"version":"4.3.4"},"reference-count":45,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T00:00:00Z","timestamp":1681689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Anxiety disorders remain underdiagnosed and undertreated, especially in child and adolescent populations. This study aimed to examine the construct validity of the Generalized Anxiety Disorder Scale 7 (GAD-7) in a sample of French adolescents by combining the Classical Test Theory (CTT) and the Item Response Theory (IRT) and to assess the invariance of items. A total of 284 adolescents enrolled in school in the Lorraine region were randomly selected to participate in a cross-sectional study. A psychometric evaluation was performed using a combination of CTT and IRT analyses. The study of psychometric properties of GAD-7 revealed poor adequation to the sample population, and engendered the deletion of one item (#7) and the merger of two response modalities (#2 and #3). These modifications generated the new GAD-6 scale, which had a good internal consistency reliability (Cronbach \u03b1 = 0.85; PSI = 0.83), acceptable goodness-of-fit indices (\u03c72 = 28.89, df = 9, P = 0.001; RMSEA (90% CI) = 0.088 [0.054; 0.125]; SRMR = 0.063; CFI = 0.857), and an acceptable convergent validity (r = \u20130.62). Only one item (#5) had a consistent Differential Item Functioning (DIF) by gender. This study evaluated the structure of the GAD-7 scale, which was essentially intended at discriminating adolescent patients with high levels of anxiety, and adapted it to a population of adolescents from the general population. The GAD-6 scale presents better psychometric properties in this general population than the original GAD-7 version.<\/jats:p>","DOI":"10.3390\/ijerph20085546","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T02:30:03Z","timestamp":1681785003000},"page":"5546","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Validation of Generalized Anxiety Disorder 6 (GAD-6)\u2014A Modified Structure of Screening for Anxiety in the Adolescent French Population"],"prefix":"10.3390","volume":"20","author":[{"given":"Anja","family":"Todorovi\u0107","sequence":"first","affiliation":[{"name":"UR4360 APEMAC, School of Public Health, Faculty of Medicine, University of Lorraine, 54000 Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9dric","family":"Baumann","sequence":"additional","affiliation":[{"name":"UR4360 APEMAC, School of Public Health, Faculty of Medicine, University of Lorraine, 54000 Nancy, France"},{"name":"Methodology, Data Management and Statistics Unit, University Hospital of Nancy, 54000 Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Blanchin","sequence":"additional","affiliation":[{"name":"SPHERE U1246, University of Nantes, University of Tours, INSERM, 44000 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Bourion-B\u00e9d\u00e8s","sequence":"additional","affiliation":[{"name":"UR4360 APEMAC, School of Public Health, Faculty of Medicine, University of Lorraine, 54000 Nancy, France"},{"name":"Versailles Hospital, University Department of Child and Adolescent Psychiatry, 78157 Versailles-Le-Chesnay, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,17]]},"reference":[{"key":"ref_1","unstructured":"(2021, April 21). World Health Organization Adolescent Mental Health. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/adolescent-mental-health."},{"key":"ref_2","unstructured":"(2013). American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Publishing, Inc.. [5th ed.]."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1097\/00004583-200107000-00019","article-title":"Psychosocial and Risk Behavior Correlates of Youth Suicide Attempts and Suicidal Ideation","volume":"40","author":"King","year":"2001","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1001\/archpsyc.63.9.1017","article-title":"Proximal Psychiatric Risk Factors for Suicidality in Youth: The Great Smoky Mountains Study","volume":"63","author":"Foley","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1192\/bjp.164.1.69","article-title":"The Chartres Study: I. Prevalence of Psychiatric Disorders Among French School-Aged Children","volume":"164","author":"Fombonne","year":"1994","journal-title":"Br. J. Psychiatry"},{"key":"ref_6","first-page":"155","article-title":"Child Anxiety in Primary Care: Prevalent but Untreated. Depress","volume":"20","author":"Chavira","year":"2004","journal-title":"Anxiety"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"113429","DOI":"10.1016\/j.psychres.2020.113429","article-title":"Impact of COVID-19 and Lockdown on Mental Health of Children and Adolescents: A Narrative Review with Recommendations","volume":"293","author":"Singh","year":"2020","journal-title":"Psychiatry Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s00787-020-01541-4","article-title":"Prevalence and Socio-Demographic Correlates of Psychological Health Problems in Chinese Adolescents during the Outbreak of COVID-19","volume":"29","author":"Zhou","year":"2020","journal-title":"Eur. Child Adolesc. Psychiatry"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jad.2021.01.041","article-title":"Stress and Associated Factors among French University Students under the COVID-19 Lockdown: The Results of the PIMS-CoV 19 Study","volume":"283","author":"Tarquinio","year":"2021","journal-title":"J. Affect. Disord."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"113559","DOI":"10.1016\/j.psychres.2020.113559","article-title":"Psychological Impact of the COVID-19 Outbreak on Students in a French Region Severely Affected by the Disease: Results of the PIMS-CoV 19 Study","volume":"295","author":"Tarquinio","year":"2021","journal-title":"Psychiatry Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00787-012-0356-8","article-title":"Anxiety Disorders","volume":"22","author":"Mohr","year":"2013","journal-title":"Eur. Child Adolesc. Psychiatry"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"ref_13","first-page":"227A","article-title":"The Generalized Anxiety Disorder 7-Item Scale in Adolescents with Generalized Anxiety Disorder: Signal Detection and Validation","volume":"29","author":"Mossman","year":"2017","journal-title":"Ann. Clin. Psychiatry"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3109\/02813432.2014.920597","article-title":"Prevalence of Anxiety Disorders among Finnish Primary Care High Utilizers and Validation of Finnish Translation of GAD-7 and GAD-2 Screening Tools","volume":"32","author":"Jokelainen","year":"2014","journal-title":"Scand. J. Prim. Health Care"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.psychres.2018.12.004","article-title":"Psychometric Properties of the 7-Item Generalized Anxiety Disorder Scale (GAD-7) in a Large Representative Sample of Finnish Adolescents","volume":"272","author":"Tiirikainen","year":"2019","journal-title":"Psychiatry Res."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.yebeh.2016.02.015","article-title":"Rapid Detection of Generalized Anxiety Disorder and Major Depression in Epilepsy: Validation of the GAD-7 as a Complementary Tool to the NDDI-E in a French Sample","volume":"57","author":"Lagarde","year":"2016","journal-title":"Epilepsy Behav."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/MLR.0b013e318160d093","article-title":"Validation and Standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the General Population","volume":"46","author":"Decker","year":"2008","journal-title":"Med. Care"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Lovero, K.L., Adam, S.E., Bila, C.E., Canda, E.D., Fernandes, M.E., Rodrigues, T.I.B., Sander, M.C.T., Mellins, C.A., Duarte, C.S., and Dos Santos, P.F. (2022). Validation of Brief Screening Instruments for Internalizing and Externalizing Disorders in Mozambican Adolescents. BMC Psychiatry, 22.","DOI":"10.1186\/s12888-022-04189-3"},{"key":"ref_19","first-page":"241","article-title":"Psychometric Properties of the Generalized Anxiety Disorder\u20147 Item Scale (GAD-7) in Youth: Screening in a Primary Care Sample","volume":"33","author":"Hughes","year":"2021","journal-title":"Ann. Clin. Psychiatry"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1007\/s10802-022-00940-2","article-title":"Depression and Anxiety Symptoms amongst Kenyan Adolescents: Psychometric Properties, Prevalence Rates and Associations with Psychosocial Wellbeing and Sociodemographic Factors","volume":"50","author":"Osborn","year":"2022","journal-title":"Res. Child Adolesc. Psychopathol."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Ip, H., Suen, Y.N., Hui, C.L.M., Wong, S.M.Y., Chan, S.K.W., Lee, E.H.M., Wong, M.T.H., and Chen, E.Y.H. (2022). Assessing Anxiety among Adolescents in Hong Kong: Psychometric Properties and Validity of the Generalised Anxiety Disorder-7 (GAD-7) in an Epidemiological Community Sample. BMC Psychiatry, 22.","DOI":"10.1186\/s12888-022-04329-9"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"458","DOI":"10.4067\/S0034-98872022000400458","article-title":"Propiedades Psicom\u00e9tricas de La Escala Generalized Anxiety Disorder 7-Item (GAD-7) En Una Muestra Comunitaria de Adolescentes En Chile","volume":"150","author":"Crockett","year":"2022","journal-title":"Rev. M\u00e9d. Chile"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1097\/01.mlr.0000245426.10853.30","article-title":"Classical Test Theory","volume":"44","author":"DeVellis","year":"2006","journal-title":"Med. Care"},{"key":"ref_24","first-page":"171","article-title":"Item Response Theory for Measurement Validity","volume":"26","author":"Yang","year":"2014","journal-title":"Shanghai Arch. Psychiatry"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1177\/0013164415576958","article-title":"On the Relationship Between Classical Test Theory and Item Response Theory: From One to the Other and Back","volume":"76","author":"Raykov","year":"2016","journal-title":"Educ. Psychol. Meas."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s11136-014-0772-y","article-title":"Combination of Classical Test Theory (CTT) and Item Response Theory (IRT) Analysis to Study the Psychometric Properties of the French Version of the Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF)","volume":"24","author":"Schwan","year":"2015","journal-title":"Qual. Life Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s40471-019-00194-5","article-title":"Differential Item Functioning and Its Relevance to Epidemiology","volume":"6","author":"Jones","year":"2019","journal-title":"Curr. Epidemiol. Rep."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s12955-015-0365-7","article-title":"Differential Item Functioning (DIF) of SF-12 and Q-LES-Q-SF Items among French Substance Users","volume":"13","author":"Schwan","year":"2015","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1007\/s11136-007-9241-1","article-title":"Testing the Structural and Cross-Cultural Validity of the KIDSCREEN-27 Quality of Life Questionnaire","volume":"16","author":"Robitail","year":"2007","journal-title":"Qual. Life Res."},{"key":"ref_30","unstructured":"(1994). American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Publishing, Inc.. [4th ed.]."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/j.1524-4733.2007.00291.x","article-title":"The KIDSCREEN-52 Quality of Life Measure for Children and Adolescents: Psychometric Results from a Cross-Cultural Survey in 13 European Countries","volume":"11","author":"Gosch","year":"2008","journal-title":"Value Health"},{"key":"ref_32","unstructured":"Ravens-Sieberer, U., and Kidscreen Group Europe (2016). The Kidscreen Questionnaires: Quality of Life Questionnaires for Children and Adolescents: Handbook, Pabst Science Publishers. [3rd ed.]."},{"key":"ref_33","unstructured":"Blanchin, M., and Brisson, P. (2020). ROSALI: Stata Module to Detect of Response Shift at Item-Level between Two Times of Measurement, Boston College Department of Economics."},{"key":"ref_34","first-page":"23","article-title":"Evaluating the Fit of Structural Equation Models: Tests of Significance and Descriptive Goodness-of-Fit Measures","volume":"8","author":"Moosbrugger","year":"2003","journal-title":"Methods Psychol. Res."},{"key":"ref_35","unstructured":"Yu, C.-Y. (2002). Evaluating Cutoff Criteria of Model Fit Indices for Latent Variable Models with Binary and Continuous Outcomes, University of California."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1002\/sim.941","article-title":"Quality of Life. Assessment, Analysis and Interpretation. P. M. Fayers and D. Machin, Wiley, Chichester, 2000. No. of Pages: Xii +404. Price: \u00a360.00. ISBN 0-471-96861-7: BOOK REVIEW","volume":"20","author":"Petersen","year":"2001","journal-title":"Statist. Med."},{"key":"ref_37","unstructured":"Dickes, P. (1994). La Psychom\u00e9trie: Th\u00e9ories et M\u00e9thodes de la Mesure en Psychologie, Presses Universitaires de France. [1st ed.]. Le Psychologue."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Abma, I.L., Rovers, M., and van der Wees, P.J. (2016). Appraising Convergent Validity of Patient-Reported Outcome Measures in Systematic Reviews: Constructing Hypotheses and Interpreting Outcomes. BMC Res. Notes, 9.","DOI":"10.1186\/s13104-016-2034-2"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1477-7525-1-27","article-title":"Classical Test Theory versus Rasch Analysis for Quality of Life Questionnaire Reduction","volume":"1","author":"Prieto","year":"2003","journal-title":"Health Qual Life Outcomes"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"613482","DOI":"10.3389\/fpsyg.2020.613482","article-title":"How to Investigate the Effects of Groups on Changes in Longitudinal Patient-Reported Outcomes and Response Shift Using Rasch Models","volume":"11","author":"Hammas","year":"2020","journal-title":"Front. Psychol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jad.2014.08.004","article-title":"Psychometric Properties of the 7-Item Generalized Anxiety Disorder Scale in Antepartum Women from Ghana and C\u00f4te d\u2019Ivoire","volume":"169","author":"Barthel","year":"2014","journal-title":"J. Affect. Disord."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1177\/0146621616664304","article-title":"After Differential Item Functioning Is Detected: IRT Item Calibration and Scoring in the Presence of DIF","volume":"40","author":"Cho","year":"2016","journal-title":"Appl. Psychol. Meas."},{"key":"ref_43","unstructured":"(2023, March 16). CNIL Donn\u00e9e Sensible|CNIL. Available online: https:\/\/www.cnil.fr\/fr\/definition\/donnee-sensible."},{"key":"ref_44","unstructured":"(2023, March 16). European Commission What Personal Data Is Considered Sensitive?. Available online: https:\/\/commission.europa.eu\/law\/law-topic\/data-protection\/reform\/rules-business-and-organisations\/legal-grounds-processing-data\/sensitive-data\/what-personal-data-considered-sensitive_en."},{"key":"ref_45","unstructured":"(2023, April 03). General Data Protection Regulation (GDPR)\u2014Official Legal Text. Available online: https:\/\/gdpr-info.eu\/."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/8\/5546\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:17:32Z","timestamp":1760123852000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/8\/5546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,17]]},"references-count":45,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["ijerph20085546"],"URL":"https:\/\/doi.org\/10.3390\/ijerph20085546","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,17]]}}}