{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T08:46:52Z","timestamp":1784278012846,"version":"3.55.0"},"reference-count":38,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institute of Health","award":["5D43TW011394-02"],"award-info":[{"award-number":["5D43TW011394-02"]}]},{"name":"National Institute of Health","award":["R01AG064688"],"award-info":[{"award-number":["R01AG064688"]}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging (NIA) of the National Institutes of Health (NIH)","doi-asserted-by":"publisher","award":["5D43TW011394-02"],"award-info":[{"award-number":["5D43TW011394-02"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging (NIA) of the National Institutes of Health (NIH)","doi-asserted-by":"publisher","award":["R01AG064688"],"award-info":[{"award-number":["R01AG064688"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Better understanding of the quality of life among nursing home residents with dementia is important for developing interventions. The objectives of this cross-sectional study were to examine factors associated with poor health-related quality of life in older people with dementia living in nursing homes in Hanoi, Vietnam. In-person interviews were conducted with 140 adults who were 60 years and older with dementia, and information about their quality of life was obtained using the Quality of Life in Alzheimer\u2019s Disease (QOL-AD) scale. The sociodemographic and clinical factors associated with poor health-related quality of life (lowest quartile) were assessed through the results of physical tests, interviews with nursing home staff, and review of medical records. The average age of the study sample was 78.3 years, 65% were women, and their average QOL-AD total score was 27.3 (SD = 4.4). Malnutrition, total dependence in activities of daily living, and urinary incontinence were associated with poor quality of life after controlling for multiple potentially confounding factors. Our findings show that Vietnamese nursing home residents with dementia have a moderate total quality of life score, and interventions based on comprehensive geriatric assessment remain needed to modify risk factors related to poor health-related quality of life.<\/jats:p>","DOI":"10.3390\/ijerph21020135","type":"journal-article","created":{"date-parts":[[2024,1,26]],"date-time":"2024-01-26T04:05:46Z","timestamp":1706241946000},"page":"135","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Health-Related Quality of Life among Older Adults with Dementia Living in Vietnamese Nursing Homes"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9858-9268","authenticated-orcid":false,"given":"Thanh Xuan","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Geriatrics, Hanoi Medical University, Hanoi 100000, Vietnam"},{"name":"National Geriatric Hospital, Hanoi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6804-0154","authenticated-orcid":false,"given":"Anh Huynh Phuong","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huong Thi Thu","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Hanoi Medical University, Hanoi 100000, Vietnam"},{"name":"National Geriatric Hospital, Hanoi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thu Thi Hoai","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Hanoi Medical University, Hanoi 100000, Vietnam"},{"name":"National Geriatric Hospital, Hanoi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4998-8510","authenticated-orcid":false,"given":"Hoa Lan","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert Joel","family":"Goldberg","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janani","family":"Thillainadesan","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Centre for Education and Research on Ageing (CERA), Concord Hospital, Sydney, NSW 2139, Australia"},{"name":"Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasi","family":"Naganathan","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Centre for Education and Research on Ageing (CERA), Concord Hospital, Sydney, NSW 2139, Australia"},{"name":"Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3132-3801","authenticated-orcid":false,"given":"Huyen Thi Thanh","family":"Vu","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Hanoi Medical University, Hanoi 100000, Vietnam"},{"name":"National Geriatric Hospital, Hanoi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc Viet","family":"Tran","sequence":"additional","affiliation":[{"name":"National Geriatric Hospital, Hanoi 100000, Vietnam"},{"name":"Neurology Department, Hanoi Medical University, Hanoi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4938-8582","authenticated-orcid":false,"given":"Anh Trung","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Hanoi Medical University, Hanoi 100000, Vietnam"},{"name":"National Geriatric Hospital, Hanoi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.amjmed.2018.01.022","article-title":"Acar in KR Daffner","volume":"131","author":"Gale","year":"2018","journal-title":"Am. J. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/alz.12635","article-title":"Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals","volume":"19","author":"Chung","year":"2023","journal-title":"Alzheimers Dement."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e007409","DOI":"10.1136\/bmjgh-2021-007409","article-title":"The economic burden of dementia in low- and middle-income countries (LMICs): A systematic review","volume":"7","author":"Mattap","year":"2022","journal-title":"BMJ Glob. Health"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jamda.2013.09.010","article-title":"Quality of life and quality of care for people with dementia receiving long term institutional care\nor professional home care: The European RightTimePlaceCare study","volume":"15","author":"Beerens","year":"2014","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"The Whoqol Group (1998). The World Health Organization Quality of Life Assessment (WHOQOL): Development and general psychometric properties. Soc. Sci. Med., 46, 1569\u20131585.","DOI":"10.1016\/S0277-9536(98)00009-4"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1159\/000515317","article-title":"Quality of Life Assessment in Older Adults with Dementia: A Systematic Review","volume":"50","author":"Burks","year":"2021","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.ijnurstu.2013.02.005","article-title":"Factors associated with quality of life of people with dementia in long-term care facilities: A systematic review","volume":"50","author":"Beerens","year":"2013","journal-title":"Int. J. Nurs. Stud."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Gan, J., Chen, Z., Liu, S., Shi, Z., Liu, Y., Wang, X.-D., Liu, C., and Ji, Y. (2022). The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia. BMC Neurol., 22.","DOI":"10.1186\/s12883-022-02897-7"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/ggi.12217","article-title":"Comprehensive geriatric assessment in elderly patients with dementia","volume":"15","author":"Namioka","year":"2015","journal-title":"Geriatr. Gerontol. Int."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1590\/S1980-57642008DN10300013","article-title":"Comprehensive geriatric assessment in elderly outpatients with dementia","volume":"1","author":"Aliberti","year":"2007","journal-title":"Dement. Neuropsychol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1186\/s12955-020-01554-2","article-title":"Quality of life and factors affecting it in patients with Alzheimer\u2019s disease: A cross-sectional study","volume":"18","author":"Akyol","year":"2020","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3792","DOI":"10.1111\/jan.14199","article-title":"Nursing home care for people with dementia: Update of the design of the Living Arrangements for people with Dementia (LAD)-study","volume":"75","author":"Prins","year":"2019","journal-title":"J. Adv. Nurs."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2055102920954710","DOI":"10.1177\/2055102920954710","article-title":"Quality of life of older adults in nursing homes in Vietnam","volume":"7","author":"Dung","year":"2020","journal-title":"Health Psychol. Open"},{"key":"ref_14","unstructured":"UNFPA (2021, November 20). Market Outlook for Elderly Care Service in Vietnam. Available online: https:\/\/vietnam.unfpa.org\/en\/publications\/market-outlook-elderly-care-services-vietnam."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.cger.2014.04.001","article-title":"Dementia and cognitive impairment: Epidemiology, diagnosis, and treatment","volume":"30","author":"Hugo","year":"2014","journal-title":"Clin. Geriatr. Med."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Urqueta Alfaro, A., Guthrie, D.M., Phillips, N.A., Pichora-Fuller, M.K., Mick, P., McGraw, C., and Wittich, W. (2019). Detection of vision and\/or hearing loss using the interRAI Community Health Assessment aligns well with common behavioral vision\/hearing measurements. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0223123"},{"key":"ref_17","first-page":"82","article-title":"Assessing quality of life in Alzheimer\u2019s disease: Implications for clinical trials","volume":"6","author":"Ye","year":"2017","journal-title":"Alzheimers Dement."},{"key":"ref_18","unstructured":"Varghese, D., Ishida, C., and Koya, H.H. (2023). Polypharmacy, StatPearls."},{"key":"ref_19","unstructured":"Mitchell, A.J. (2017). Cognitive Screening Instruments: A Practical Approach, Springer."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1177\/2150131916659282","article-title":"Timed Up and Go (TUG) Test: Normative Reference Values for Ages 20 to 59 Years and Relationships With Physical and Mental Health Risk Factors","volume":"8","author":"Kear","year":"2017","journal-title":"J. Prim. Care Community Health"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/02701367.1999.10608028","article-title":"A 30-s chair-stand test as a measure of lower body strength in community-residing older adults","volume":"70","author":"Jones","year":"1999","journal-title":"Res. Q. Exerc. Sport."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.rehab.2019.08.003","article-title":"Accuracy of modified 30-s chair-stand test for predicting falls in older adults","volume":"63","author":"Roongbenjawan","year":"2020","journal-title":"Ann. Phys. Rehabil. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"M366","DOI":"10.1093\/gerona\/56.6.M366","article-title":"Screening for undernutrition in geriatric practice: Developing the short-form mini-nutritional assessment (MNA-SF)","volume":"56","author":"Rubenstein","year":"2001","journal-title":"J. Gerontol. Biol. Sci. Med. Sci."},{"key":"ref_24","first-page":"61","article-title":"Functional evaluation: The Barthel Index","volume":"14","author":"Mahoney","year":"1965","journal-title":"Md. State Med. J."},{"key":"ref_25","first-page":"62","article-title":"Advancing your practice: Urinary incontinence","volume":"102","author":"Lam","year":"2021","journal-title":"Aust. J. Pharm."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1054\/cein.2001.0234","article-title":"The Edinburgh Feeding Evaluation in Dementia Scale #2 (EdFED #2): Inter- and intra-rater reliability","volume":"5","author":"Watson","year":"2001","journal-title":"Clin. Eff. Nurs."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1212\/WNL.44.12.2308","article-title":"The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia","volume":"44","author":"Cummings","year":"1994","journal-title":"Neurology"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/ajag.12755","article-title":"Towards the development of Vietnam\u2019s national dementia plan-the first step of action","volume":"39","author":"Nguyen","year":"2020","journal-title":"Australas. J. Ageing"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"de Boer, B., Hamers, J.P., Zwakhalen, S.M., Tan, F.E., and Verbeek, H. (2017). Quality of care and quality of life of people with dementia living at green care farms: A cross-sectional study. BMC Geriatr., 17.","DOI":"10.1186\/s12877-017-0550-0"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s11136-019-02333-3","article-title":"Exploring self-report and proxy-report quality-of-life measures for people living with dementia in care homes","volume":"29","author":"Griffiths","year":"2020","journal-title":"Qual. Life Res."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1192\/bjp.bp.104.007658","article-title":"Quality of life of people with dementia in residential care homes","volume":"188","author":"Hoe","year":"2006","journal-title":"Br. J. Psychiatry"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1046\/j.1532-5415.2003.51471.x","article-title":"Best paper of the 1980s: National Institutes of Health Consensus Development Conference Statement: Geriatric assessment methods for clinical decision-making. 1988","volume":"51","author":"Solomon","year":"2003","journal-title":"J. Am. Geriatr. Soc."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1146899","DOI":"10.3389\/fpubh.2023.1146899","article-title":"Association between multimorbidity and falls and fear of falling among older adults in eastern China: A cross-sectional study","volume":"11","author":"You","year":"2023","journal-title":"Front. Public Health"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.cger.2020.06.002","article-title":"Multimorbidity, Function, and Cognition in Aging","volume":"36","author":"Kadambi","year":"2020","journal-title":"Clin. Geriatr. Med."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"11643","DOI":"10.1038\/s41598-022-15723-4","article-title":"Multimorbidity patterns and hospitalisation occurrence in adults and older adults aged 50 years or over","volume":"12","author":"Rodrigues","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/ageing\/afw044","article-title":"Associations between multimorbidity, healthcare utilisation and health status: Evidence from 16 European countries","volume":"45","author":"Palladino","year":"2016","journal-title":"Age Ageing"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s11136-022-03317-6","article-title":"Chronic physical conditions, physical multimorbidity, and quality of life among adults aged\u2009\u226550 years from six low- and middle-income countries","volume":"32","author":"Olanrewaju","year":"2023","journal-title":"Qual. Life Res."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/2\/135\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:49:30Z","timestamp":1760104170000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/2\/135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,25]]},"references-count":38,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["ijerph21020135"],"URL":"https:\/\/doi.org\/10.3390\/ijerph21020135","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,25]]}}}