{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:46:11Z","timestamp":1787028371244,"version":"build-2736575974"},"reference-count":28,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T00:00:00Z","timestamp":1707868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH","award":["P30ES027792"],"award-info":[{"award-number":["P30ES027792"]}]},{"name":"NIH","award":["U2RTW010122"],"award-info":[{"award-number":["U2RTW010122"]}]},{"name":"NIH","award":["#P30 ES027792"],"award-info":[{"award-number":["#P30 ES027792"]}]},{"name":"University of Chicago Medicine Comprehensive Cancer Center","award":["P30ES027792"],"award-info":[{"award-number":["P30ES027792"]}]},{"name":"University of Chicago Medicine Comprehensive Cancer Center","award":["U2RTW010122"],"award-info":[{"award-number":["U2RTW010122"]}]},{"name":"University of Chicago Medicine Comprehensive Cancer Center","award":["#P30 ES027792"],"award-info":[{"award-number":["#P30 ES027792"]}]},{"name":"NIEHS","award":["P30ES027792"],"award-info":[{"award-number":["P30ES027792"]}]},{"name":"NIEHS","award":["U2RTW010122"],"award-info":[{"award-number":["U2RTW010122"]}]},{"name":"NIEHS","award":["#P30 ES027792"],"award-info":[{"award-number":["#P30 ES027792"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Objectives: To investigate the effect of individual-level, neighborhood, and environmental variables on uterine fibroid (UF) prevalence in a Chicago-based cohort. (2) Methods: Data from the Chicago Multiethnic Prevention and Surveillance Study (COMPASS) were analyzed. Individual-level variables were obtained from questionnaires, neighborhood variables from the Chicago Health Atlas, and environmental variables from NASA satellite ambient air exposure levels. The Shapiro\u2013Wilk test, logistic regression models, and Spearman\u2019s correlations were used to evaluate the association of variables to UF diagnosis. (3) Results: We analyzed 602 participants (mean age: 50.3 \u00b1 12.3) who responded to a question about UF diagnosis. More Black than White participants had a UF diagnosis (OR, 1.32; 95% CI, 0.62\u20132.79). We observed non-significant trends between individual-level and neighborhood variables and UF diagnosis. Ambient air pollutants, PM2.5, and DSLPM were protective against UF diagnosis (OR 0.20, CI: 0.04\u20130.97: OR 0.33, CI: 0.13\u20130.87). (4) Conclusions: Associations observed within a sample in a specific geographic area may not be generalizable and must be interpreted cautiously.<\/jats:p>","DOI":"10.3390\/ijerph21020222","type":"journal-article","created":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T06:59:26Z","timestamp":1707893966000},"page":"222","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Uterine Fibroid Prevalence in a Predominantly Black, Chicago-Based Cohort"],"prefix":"10.3390","volume":"21","author":[{"given":"Sithembinkosi","family":"Ndebele","sequence":"first","affiliation":[{"name":"Department of Public Health Sciences, The University of Chicago, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tecora","family":"Turner","sequence":"additional","affiliation":[{"name":"Pritzker School of Medicine, The University of Chicago, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanhong","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, The University of Chicago, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briseis","family":"Aschebrook-Kilfoy","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, The University of Chicago, Chicago, IL 60637, USA"},{"name":"Institute for Population and Precision Health, The University of Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Randorf","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, The University of Chicago, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habibul","family":"Ahsan","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, The University of Chicago, Chicago, IL 60637, USA"},{"name":"Institute for Population and Precision Health, The University of Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunle","family":"Odunsi","sequence":"additional","affiliation":[{"name":"Comprehensive Cancer Center, The University of Chicago, Chicago IL 60637, USA"},{"name":"Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Obianuju Sandra","family":"Madueke-Laveaux","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1055\/s-0037-1607264","article-title":"Uterine Fibroids: Burden and Unmet Medical Need","volume":"35","author":"Myers","year":"2017","journal-title":"Semin. Reprod. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/AOG.0000000000004224","article-title":"Racial and Ethnic Disparities in Reproductive Health Services and Outcomes, 2020","volume":"137","author":"Sutton","year":"2021","journal-title":"Obstet. Gynecol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1097\/EDE.0b013e3181567e92","article-title":"Perceived Racial Discrimination and Risk of Uterine Leiomyomata","volume":"18","author":"Wise","year":"2007","journal-title":"Epidemiology"},{"key":"ref_4","first-page":"287","article-title":"Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention","volume":"2","author":"Igboeli","year":"2019","journal-title":"Curr. Opin. Gynecol. Obstet."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bpobgyn.2017.09.004","article-title":"Epidemiology and Risk Factors of Uterine Fibroids","volume":"46","author":"Pavone","year":"2018","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1210\/endrev\/bnab039","article-title":"Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment","volume":"43","author":"Yang","year":"2021","journal-title":"Endocr. Rev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12939-020-01327-9","article-title":"Assessing Burden, Risk Factors, and Perceived Impact of Uterine Fibroids on Women\u2019s Lives in Rural Haiti: Implications for Advancing a Health Equity Agenda, a Mixed Methods Study","volume":"20","author":"Millien","year":"2021","journal-title":"Int. J. Equity Health"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.envres.2006.05.007","article-title":"The Riskscape and the Color Line: Examining the Role of Segregation in Environmental Health Disparities","volume":"102","author":"Lopez","year":"2006","journal-title":"Environ. Res."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Tinelli, A., Vinciguerra, M., Malvasi, A., Andji\u0107, M., Babovi\u0107, I., and Spari\u0107, R. (2021). Uterine Fibroids and Diet. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18031066"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1007\/s11606-018-4607-3","article-title":"Experiences of Community Violence among Adults with Chronic Conditions: Qualitative Findings from Chicago","volume":"33","author":"Tung","year":"2018","journal-title":"J. Gen. Intern. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e024772","DOI":"10.1161\/JAHA.121.024772","article-title":"Health Consequences of Segregation and Disenfranchisement","volume":"11","author":"Kalra","year":"2022","journal-title":"J. Am. Heart Assoc."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ijheh.2019.02.004","article-title":"The Effects of Exposure to Air Pollution on the Development of Uterine Fibroids","volume":"222","author":"Lin","year":"2019","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1093\/humrep\/deab095","article-title":"A Prospective Cohort Study of Ambient Air Pollution Exposure and Risk of Uterine Leiomyomata","volume":"36","author":"Wesselink","year":"2021","journal-title":"Hum. Reprod."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1097\/EDE.0000000000000126","article-title":"Air Pollution and Risk of Uterine Leiomyomata","volume":"25","author":"Mahalingaiah","year":"2014","journal-title":"Epidemiology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11111-014-0228-x","article-title":"Chicago Residents\u2019 Perceptions of Air Quality: Objective Pollution, the Built Environment, and Neighborhood Stigma Theory","volume":"37","author":"King","year":"2014","journal-title":"Popul. Environ."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e038481","DOI":"10.1136\/bmjopen-2020-038481","article-title":"Cohort Profile: The ChicagO Multiethnic Prevention and Surveillance Study (COMPASS)","volume":"10","author":"Kibriya","year":"2020","journal-title":"BMJ Open"},{"key":"ref_17","unstructured":"(2023, May 16). Chicago Health Atlas. Available online: https:\/\/chicagohealthatlas.org\/."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s13253-014-0180-3","article-title":"Characterization of Weighted Quantile Sum Regression for Highly Correlated Data in a Risk Analysis Setting","volume":"20","author":"Carrico","year":"2015","journal-title":"J. Agric. Biol. Environ. Stat."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/aje\/kwad015","article-title":"The Impact of Neighborhood Disadvantage on Asthma Prevalence in a Predominantly African-American, Chicago-Based Cohort","volume":"192","author":"Luo","year":"2023","journal-title":"Am. J. Epidemiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3389\/fpubh.2019.00011","article-title":"Social Determinants of Health and Related Inequalities: Confusion and Implications","volume":"7","author":"Islam","year":"2019","journal-title":"Front. Public Health"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/1479-5868-7-68","article-title":"Overestimation of Physical Activity Level Is Associated with Lower BMI: A Cross-Sectional Analysis","volume":"7","author":"Watkinson","year":"2010","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1056\/NEJM199801153380307","article-title":"Protective and Damaging Effects of Stress Mediators","volume":"338","author":"McEwen","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.whi.2009.03.001","article-title":"Racial Differences in Women Who Have a Hysterectomy for Benign Conditions","volume":"19","author":"Weiss","year":"2009","journal-title":"Women\u2019s Health Issues"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1016\/j.fertnstert.2010.03.035","article-title":"Pregnancy-Related Fibroid Reduction","volume":"94","author":"Laughlin","year":"2010","journal-title":"Fertil. Steril."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/bjaed\/mkv034","article-title":"Statistical Analysis: Sample Size and Power Estimations","volume":"16","author":"Columb","year":"2016","journal-title":"BJA Educ."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1586\/14737167.4.2.159","article-title":"Patient Recall and Recall Bias of Health State and Health Status","volume":"4","author":"Schmier","year":"2004","journal-title":"Expert Rev. Pharmacoecon. Outcomes Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0029-7844(97)00534-6","article-title":"Variation in the Incidence of Uterine Leiomyoma among Premenopausal Women by Age and Race","volume":"90","author":"Marshall","year":"1997","journal-title":"Obstet. Gynecol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/01.AOG.0000154161.03418.e3","article-title":"Age-Specific Incidence Rates for Self-Reported Uterine Leiomyomata in the Black Women\u2019s Health Study","volume":"105","author":"Wise","year":"2005","journal-title":"Obstet. Gynecol."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/2\/222\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:59:31Z","timestamp":1760104771000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/2\/222"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,14]]},"references-count":28,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["ijerph21020222"],"URL":"https:\/\/doi.org\/10.3390\/ijerph21020222","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,14]]}}}