{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:13:00Z","timestamp":1780056780361,"version":"3.54.0"},"reference-count":87,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:00:00Z","timestamp":1708300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Due to the high prevalence and persistence of long COVID, it is important to evaluate the safety and efficacy of pulmonary rehabilitation (PR) for patients who experience long-lasting symptoms more than six months after initial COVID-19 onset. Enrolled patients were admitted for a four-week in-patient-PR due to long COVID symptoms (n = 47). The safety of PR was confirmed by the absence of adverse events. Symptom-related outcomes were evaluated pre- and post-PR with significant score changes for: 6 min walking distance (61 [28 to 103] m), quality of life (mental Short Form-12: 10 [6 to 13], and physical: 9 [6 to 12]), Montreal Cognitive Assessment (1 [0 to 3]), fatigue (MFI-20: \u221219 [\u221228 to \u22128]), dyspnea (DYSPNEA-12: \u22127 [\u22129 to \u22122] and mMRC; \u22121 [\u22121 to 0]), Nijmegen questionnaire (\u22128 [\u221211 to \u22125]), anxiety and depression (HADS:\u22124 [\u22125 to \u22122] and \u22122 [\u22124 to \u22121], respectively) and posttraumatic stress disorder checklist scale (\u22128 [\u221212 to \u22124]). At the individual level, the percentage of symptomatic patients for each outcome decreased, with a high response rate, and the number of persistent symptoms per patient was reduced from six at PR initiation to three at the end of the program. Our results show that in-PR is safe and efficient at decreasing long-lasting symptoms experienced by long COVID patients at more than six months after initial disease onset.<\/jats:p>","DOI":"10.3390\/ijerph21020242","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T11:23:57Z","timestamp":1708341837000},"page":"242","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Safety and Efficacy of Pulmonary Rehabilitation for Long COVID Patients Experiencing Long-Lasting Symptoms"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4579-1323","authenticated-orcid":false,"given":"Esp\u00e9rance","family":"Moine","sequence":"first","affiliation":[{"name":"Direction de la Recherche Clinique et de l\u2019Innovation en Sant\u00e9, Clariane, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Molinier","sequence":"additional","affiliation":[{"name":"Direction de la Recherche Clinique et de l\u2019Innovation en Sant\u00e9, Clariane, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Castanyer","sequence":"additional","affiliation":[{"name":"Clinique du Souffle La Solane, Inicea, 66340 Oss\u00e9ja, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandine","family":"Calvat","sequence":"additional","affiliation":[{"name":"Clinique du Souffle La Vallonie, Inicea, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Coste","sequence":"additional","affiliation":[{"name":"Clinique du Souffle La Solane, Inicea, 66340 Oss\u00e9ja, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonin","family":"Vernet","sequence":"additional","affiliation":[{"name":"Clinique du Souffle La Solane, Inicea, 66340 Oss\u00e9ja, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Faug\u00e9","sequence":"additional","affiliation":[{"name":"Clinique du Souffle La Vallonie, Inicea, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perrine","family":"Magrina","sequence":"additional","affiliation":[{"name":"Clinique du Souffle La Vallonie, Inicea, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan Lluis","family":"Aliaga-Parera","sequence":"additional","affiliation":[{"name":"Clinique du Souffle La Solane, Inicea, 66340 Oss\u00e9ja, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Oliver","sequence":"additional","affiliation":[{"name":"Direction de la Recherche Clinique et de l\u2019Innovation en Sant\u00e9, Clariane, 34700 Lod\u00e8ve, France"},{"name":"Clinique du Souffle La Vallonie, Inicea, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Alexandre","sequence":"additional","affiliation":[{"name":"Direction de la Recherche Clinique et de l\u2019Innovation en Sant\u00e9, Clariane, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly","family":"Heraud","sequence":"additional","affiliation":[{"name":"Direction de la Recherche Clinique et de l\u2019Innovation en Sant\u00e9, Clariane, 34700 Lod\u00e8ve, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1016\/S1473-3099(21)00703-9","article-title":"A clinical case definition of post-COVID-19 condition by a Delphi consensus","volume":"22","author":"Soriano","year":"2022","journal-title":"Lancet Infect. 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