{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T18:06:10Z","timestamp":1778177170239,"version":"3.51.4"},"reference-count":40,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Objective: To assess the association between clinical orthodontic indicators and oral-health-related quality of life, adjusted for socio-demographic factors, focusing on 16-year-old patients with cleft lip and\/or palate (CL\/P). Participants: One hundred and twenty-two patients with CL\/P, representing cleft-lip (CL), cleft-palate (CP), unilateral\/bilateral cleft-lip-palate (UCLP\/BCLP), enrolled in the national CLP-Team, Bergen, Norway. Method: A cross-sectional study by two orthodontists assessing the number of teeth, intermaxillary sagittal relation (ANB-angle), dental arch and occlusion of 16-year-old patients with CL\/P. All completed a digital questionnaire including self-reported socio-demographic variables, OHIP-14 questionnaire and dental aesthetics. Cross-tabulations with Pearson\u2019s Chi-square test were used to identify associations between self-reported OHRQoL and socio-demographic and clinical indicators. Multiple variable analyses were conducted with binary logistic regression analysis using the odds ratio (OR) and 95% confidence interval (CI) to assess associations between OHRQoL and clinical indicators adjusted for socio-demographic variables. Ethical approval was granted by the regional ethics committee. Results: Patients with UCLP and BCLP had poorer clinical indicators compared to patients with CL and CP (p &lt; 0.05). A total of 80% of the patients had OHIP-14 &gt; 0. The highest oral impact was reported for psychological domains and articulation and the least for functional domains. Respondents with BCLP and those with poor intermaxillary relationships (ANB &lt; 0\u00b0) reported a high impact on OHRQoL (p &lt; 0.05). No statistically significant associations between other clinical indicators and socio-demographic variables such as gender, educational aspiration, and place of residence were reported. Conclusions: The study revealed an association between severe cleft diagnosis, missing teeth, misaligned teeth, negative overjet, and poor OHRQoL, but a statistically significant association was found only between OHRQoL and poor intermaxillary sagittal relations (unfavorable profile). To improve OHRQoL among patients with clefts, there is a need for an individual follow-up and prioritization of oral healthcare.<\/jats:p>","DOI":"10.3390\/ijerph21050550","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T09:26:02Z","timestamp":1714123562000},"page":"550","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Orthodontic Status and Association with Oral-Health-Related Quality of Life\u2014A Study of 16-Year-Old Norwegians with a Cleft Lip and Palate"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5216-7724","authenticated-orcid":false,"given":"Paul K.","family":"Saele","sequence":"first","affiliation":[{"name":"Oral Health Centre of Expertise\/Western Norway and Department of Clinical Dentistry, University of Bergen, 5009 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manal","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Oral Health Centre of Expertise\/Western Norway and Department of Clinical Dentistry, University of Bergen, 5009 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2707-6115","authenticated-orcid":false,"given":"Anne N.","family":"\u00c5str\u00f8m","sequence":"additional","affiliation":[{"name":"Oral Health Centre of Expertise\/Western Norway and Department of Clinical Dentistry, University of Bergen, 5009 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,26]]},"reference":[{"key":"ref_1","first-page":"216","article-title":"Incidence of cleft lip, cleft palate, and cleft lip and palate among races: A review","volume":"24","author":"Vanderas","year":"1987","journal-title":"Cleft Palate J."},{"key":"ref_2","first-page":"203","article-title":"Incidence and prevalence of cleft lip and palate","volume":"27","author":"Sayetta","year":"1990","journal-title":"Cleft Palate J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/ejo\/cjr074","article-title":"The prevalence of various dental characteristics in the primary and mixed dentition in patients born with non-syndromic unilateral cleft lip with or without cleft palate","volume":"34","author":"Pegelow","year":"2012","journal-title":"Eur. 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