{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T07:28:35Z","timestamp":1782804515978,"version":"3.54.5"},"reference-count":47,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T00:00:00Z","timestamp":1715904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: Parental mental disorders in families are frequently accompanied with other problems. These include family life, the development of children, and the social and economic environment. Mental health services often focus treatments on the individual being referred, with little attention to parenting, the family, child development, and environmental factors. This is despite the fact that there is substantial evidence to suggest that the children of these parents are at increased risk of developing a mental disorder throughout the course of their lives. Young children are particularly vulnerable to environmental influences given the level of dependency in this stage of development. Objective: The main objective of this study was to identify whether there were a complexity of problems and risks in a clinical sample of patients and their young children (0\u20136) in mental health care, and, if so, whether this complexity was reflected in the integrated treatment given. Methods: The data were collected for 26 risk factors, based on the literature, and then subdivided into the parental, child, family, and environmental domains. The data were obtained from the electronic case files of 100 patients at an adult mental health service and the corresponding 100 electronic case files of their infants at a child mental health service. Results: The findings evidenced a notable accumulation of risk factors within families, with a mean number of 8.43 (SD 3.2) risk factors. Almost all of the families had at least four risk factors, more than half of them had between six and ten risk factors, and a quarter of them had between eleven and sixteen risk factors. Furthermore, two-thirds of the families had at least one risk factor in each of the four domains. More than half of the families received support from at least two organizations in addition to the involvement of adult and child mental health services, which is also an indication of the presence of cumulative problems. Conclusion: This study of a clinical sample shows clearly that the mental disorder among most of the patients, who were all parents of young children, was only one of the problems they had to deal with. The cumulation of risk factors\u2014especially in the family domain\u2014increased the risk of the intergenerational transmission of mental disorders. To prevent these parents and their young children being caught up in this intergenerational cycle, a broad assessment is needed. In addition, malleable risk factors should be addressed in treatment and in close collaboration with other services.<\/jats:p>","DOI":"10.3390\/ijerph21050640","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T09:10:22Z","timestamp":1715937022000},"page":"640","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Integrated Family Approach in Mental Health Care Services: A Study of Risk Factors"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8897-312X","authenticated-orcid":false,"given":"Hanna","family":"Stolper","sequence":"first","affiliation":[{"name":"Department of Psychology Education and Child Studies, Erasmus University Rotterdam (EUR), 3062 PA Rotterdam, The Netherlands"},{"name":"Jeugd ggz Dimencegroep, 8017 CA Zwolle, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein","family":"van der Vegt","sequence":"additional","affiliation":[{"name":"Jeugd ggz Dimencegroep, 8017 CA Zwolle, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"van Doesum","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology, Radboud University Nijmegen, 6525 XZ Nijmegen, The Netherlands"},{"name":"Impluz Dimencegroep, 7411 GT Deventer, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majone","family":"Steketee","sequence":"additional","affiliation":[{"name":"Department of Psychology Education and Child Studies, Erasmus University Rotterdam (EUR), 3062 PA Rotterdam, The Netherlands"},{"name":"Verwey-Jonker Instituut, 3522 KE Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/wps.21147","article-title":"Transdiagnostic risk of mental disorders in offspring of affected parents: A meta-analysis of family high-risk and registry studies","volume":"22","author":"Uher","year":"2023","journal-title":"World Psychiatry"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1176\/appi.ajp.2016.15101327","article-title":"Offspring of depressed parents: 30 years later","volume":"173","author":"Weissman","year":"2016","journal-title":"Am. J. Psychiatry"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3389\/fpsyt.2019.00118","article-title":"Developmental trajectories of early life stress and trauma: A narrative review on neurobiological aspects beyond stress system dysregulation","volume":"10","author":"Agorastos","year":"2019","journal-title":"Front. Psychiatry"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.neubiorev.2017.07.003","article-title":"Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy","volume":"117","author":"Lahti","year":"2020","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.5172\/jamh.8.3.250","article-title":"Prevention of emotional problems and psychiatric risks in children of parents with a mental illness in the Netherlands: I. The scientific basis to a comprehensive approach","volume":"8","author":"Hosman","year":"2009","journal-title":"Aust. e-J. Adv. Ment. Health"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1192\/bjp.bp.110.080499","article-title":"Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys","volume":"197","author":"Kessler","year":"2010","journal-title":"Br. J. Psychiatry"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jpsychires.2014.07.014","article-title":"The cumulative effect of different childhood trauma types on self-reported symptoms of adult male depression and PTSD, substance abuse and health-related quality of life in a large active-duty military cohort","volume":"58","author":"Agorastos","year":"2014","journal-title":"J. Psychiatr. Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1192\/bjp.bp.111.092346","article-title":"Relative impact of maternal depression and associated risk factors on offspring psychopathology","volume":"200","author":"Barker","year":"2012","journal-title":"Br. J. Psychiatry"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1037\/a0031808","article-title":"Cumulative risk and child development","volume":"139","author":"Evans","year":"2013","journal-title":"Psychol. Bull."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1017\/S0954579409990289","article-title":"Attachment security and disorganization in maltreating and high-risk families: A series of meta-analyses","volume":"22","author":"Cyr","year":"2010","journal-title":"Dev. Psychopathol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.jaac.2012.05.004","article-title":"Recovering From Early Deprivation: Attachment Mediates Effects of Caregiving on Psychopathology","volume":"51","author":"McGoron","year":"2012","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.chc.2009.03.001","article-title":"Disturbances of Attachment and Parental Psychopathology in Early Childhood","volume":"18","author":"Schechter","year":"2009","journal-title":"Child Adolesc. Psychiatr. Clin. N. Am."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Luthar, S.S. (2003). Resilience and Vulnerability: Adaptation in the Context of Childhood Adversities, Cambridge University Press.","DOI":"10.1017\/CBO9780511615788"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"745800","DOI":"10.3389\/fpsyg.2021.745800","article-title":"How to support parents of infants and young children in mental health care: A narrative review","volume":"12","author":"Stolper","year":"2021","journal-title":"Front. Psychol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.jad.2017.12.050","article-title":"Simultaneous social causation and social drift: Longitudinal analysis of depression and poverty in South Africa","volume":"229","author":"Lund","year":"2018","journal-title":"J. Affect. Disord."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.physbeh.2011.12.008","article-title":"Mismatch or cumulative stress: Toward an integrated hypothesis of programming effects","volume":"106","author":"Nederhof","year":"2012","journal-title":"Physiol. Behav."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1469-7610.2004.00351.x","article-title":"When more is not better: The role of cumulative risk in child behavior outcomes","volume":"46","author":"Appleyard","year":"2005","journal-title":"J. Child Psychol. Psychiatry"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1176\/appi.ajp.160.8.1453","article-title":"Relationship between multiple forms of childhood maltreatment and adult mental health in community respondents: Results from the Adverse Childhood Experiences Study","volume":"160","author":"Edwards","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.amepre.2019.04.001","article-title":"Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) Study","volume":"56","author":"Felitti","year":"2019","journal-title":"Am. J. Prev. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/j.1530-0277.2011.01695.x","article-title":"Impact of multiple types of childhood trauma exposure on risk of psychiatric comorbidity among alcoholic inpatients","volume":"36","author":"Huang","year":"2012","journal-title":"Alcoholism"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s10560-018-0532-x","article-title":"Wellbeing outcomes for children exposed to multiple adverse experiences in early childhood: A systematic review","volume":"35","author":"Liming","year":"2018","journal-title":"Child Adolesc. Soc. Work J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0749-3797(98)00017-8","article-title":"Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults","volume":"14","author":"Felitti","year":"1998","journal-title":"Am. J. Prev. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"101997","DOI":"10.1016\/j.cpr.2021.101997","article-title":"Intergenerational transmission and prevention of adverse childhood experiences (ACEs)","volume":"85","author":"Narayan","year":"2021","journal-title":"Clin. Psychol. Rev."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"104051","DOI":"10.1016\/j.chiabu.2019.104051","article-title":"Self-reported adverse childhood experiences and quality of life among children in the two last grades of Dutch elementary education","volume":"95","author":"Vink","year":"2019","journal-title":"Child Abuse Neglect."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1146\/annurev-clinpsy-081219-120307","article-title":"Resilience in development and psychopathology: Multisystem perspectives","volume":"17","author":"Masten","year":"2021","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1177\/10634266040120040201","article-title":"Diversity of outcomes among adolescent children of mothers with mental illness","volume":"12","author":"Mowbray","year":"2004","journal-title":"J. Emot. Behav. Disord."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1037\/amp0000768","article-title":"All adverse childhood experiences are not equal: The contribution of synergy to adverse childhood experience scores","volume":"76","author":"Briggs","year":"2021","journal-title":"Am. Psychol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1007\/s10995-017-2365-1","article-title":"Adverse Childhood Experiences and Child Health Outcomes: Comparing Cumulative Risk and Latent Class Approaches","volume":"22","author":"Lanier","year":"2018","journal-title":"Matern. Child Health J."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1016\/S0140-6736(14)61277-0","article-title":"Effects of perinatal mental disorders on the fetus and child","volume":"384","author":"Stein","year":"2014","journal-title":"Lancet"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"781556","DOI":"10.3389\/fpsyt.2022.781556","article-title":"Integrated family approach in mental health care by professionals from adult and child mental health services: A qualitative study","volume":"13","author":"Stolper","year":"2022","journal-title":"Front. Psychiatry"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1298268","DOI":"10.3389\/fpsyt.2024.1298268","article-title":"An integrated family approach in the practice of adult and child mental health care","volume":"15","author":"Stolper","year":"2024","journal-title":"Front. Psychiatry"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Furber, G., Segal, L., Leach, M., Turnbull, C., Procter, N., Diamond, M., Miller, S., and McGorry, P. (2015). Preventing mental illness: Closing the evidence-practice gap through workforce and services planning. BMC Health Serv. Res., 15.","DOI":"10.1186\/s12913-015-0954-5"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/inm.12120","article-title":"Standards of practice for the adult mental health workforce: Meeting the needs of families where a parent has a mental illness","volume":"24","author":"Goodyear","year":"2015","journal-title":"Int. J. Ment. Health Nurs."},{"key":"ref_34","first-page":"259","article-title":"Social determinants of mental health: A review of the evidence","volume":"30","author":"Silva","year":"2016","journal-title":"Eur. J. Psychiatry"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/famp.12144","article-title":"Multiproblem families referred to youth mental health: What\u2019s in a name?","volume":"55","author":"Bodden","year":"2016","journal-title":"Fam. Process"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2330880","DOI":"10.1080\/20008066.2024.2330880","article-title":"Childhood adversity in a youth psychiatric population: Prevalence and associated mental health problems","volume":"15","author":"Knipschild","year":"2024","journal-title":"Eur. J. Psychotraumatol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1001\/jamapsychiatry.2023.4900","article-title":"Sociocultural risk and resilience in the context of adverse childhood experiences","volume":"81","author":"VanBronkhorst","year":"2024","journal-title":"JAMA Psychiatry"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s10578-017-0709-0","article-title":"The relations between maternal prenatal anxiety or stress and child\u2019s early negative reactivity or self-regulation: A systematic review","volume":"48","author":"Korja","year":"2017","journal-title":"Child Psychiatry Hum. Dev."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3389\/fpsyt.2019.00391","article-title":"Fetal and infant outcomes in the offspring of parents with perinatal mental disorders: Earliest influences","volume":"10","author":"Aktar","year":"2019","journal-title":"Front. Psychiatry"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Sell, M., Daubmann, A., Zapf, H., Adema, B., Busmann, M., Stiawa, M., Winter, S.M., Lambert, M., Wegscheider, K., and Wiegand-Grefe, S. (2021). Family functioning in families affected by parental mental illness: Parent, child, and clinician ratings. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18157985"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Wiegand-Grefe, S., Sell, M., Filter, B., and Plass-Christl, A. (2019). Family functioning and psychological health of children with mentally ill parents. Int. J. Environ. Res. Public Health, 16.","DOI":"10.3390\/ijerph16071278"},{"key":"ref_42","first-page":"974","article-title":"Ten years of infant mental health in the Netherlands: Who are the clients?","volume":"16","author":"Dekelver","year":"2020","journal-title":"Ment. Health Fam. Med."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/imhj.10061","article-title":"Diagnostic classification: Results from a clinical experience of three years with DC: 0\u20133","volume":"24","author":"Cordeiro","year":"2003","journal-title":"Infant Ment. Health J."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1365-2206.2008.00586.x","article-title":"Fostering family resiliency: A review of the key protective factors","volume":"14","author":"Benzies","year":"2009","journal-title":"Child Fam. Soc. Work"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Boulton, J.G., Allen, P.M., and Bowman, C. (2015). Embracing Complexity: Strategic Perspectives for an Age of Turbulence, Oxford University Press.","DOI":"10.1093\/acprof:oso\/9780199565252.001.0001"},{"key":"ref_46","unstructured":"Sameroff, A.J., McDonough, S.C., and Rosenblum, K.L. (2004). Treating Parent-Infant Relationship Problems: Strategies for Intervention, The Guilford Press."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Stolper, H., van Doesum, K., Henselmans, P., Bijl, A.L., and Steketee, M. (2022). The patient\u2019s voice as a parent in mental health care: A qualitative study. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph192013164"}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/5\/640\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:44:08Z","timestamp":1760107448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/5\/640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,17]]},"references-count":47,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,5]]}},"alternative-id":["ijerph21050640"],"URL":"https:\/\/doi.org\/10.3390\/ijerph21050640","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,17]]}}}