{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:21:27Z","timestamp":1789564887501,"version":"build-2803163510"},"reference-count":15,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>This study investigates the long-term efficacy of carpal tunnel release surgery (CTR) on patient outcomes. We aimed to assess symptom severity, functional limitations, and quality of life in a large cohort (n = 186) at least five years post-surgery via a retrospective cross-sectional design that evaluated participants using the validated Boston Carpal Tunnel Questionnaire (BCTQ) over a phone interview. The BCTQ measures symptom severity, functional limitations, and quality of life specific to carpal tunnel syndrome. Seventy-three percent (73.1%) of patients reported complete resolution of symptoms and functional limitations (BCTQ = 1) with an average follow-up of 11 years. No statistically significant decline in BCTQ scores was observed over time. Univariate analysis revealed a significant association between poorer outcomes and older age at surgery and current unemployment. Carpal tunnel release surgery demonstrates long-term effectiveness in relieving symptoms and improving function in most patients. These findings contribute to the understanding of CTR\u2019s impact on patient well-being beyond short-term outcomes.<\/jats:p>","DOI":"10.3390\/ijerph21091203","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T07:59:46Z","timestamp":1726041586000},"page":"1203","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Long-Term Functional Outcomes and Quality of Life Following Carpal Tunnel Release Surgery"],"prefix":"10.3390","volume":"21","author":[{"given":"Yuval","family":"Krieger","sequence":"first","affiliation":[{"name":"Hand Unit, Plastic and Reconstructive Surgery, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2276-521X","authenticated-orcid":false,"given":"Mai","family":"Ofri","sequence":"additional","affiliation":[{"name":"Soroka Clinical Research Center, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gali","family":"Sagi","sequence":"additional","affiliation":[{"name":"Department of Public Health Epidemiology, Biostatistics and Community Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hila","family":"Moshe-Noach","sequence":"additional","affiliation":[{"name":"Department of Public Health Epidemiology, Biostatistics and Community Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pnina","family":"Raiden","sequence":"additional","affiliation":[{"name":"Department of Public Health Epidemiology, Biostatistics and Community Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6222-5657","authenticated-orcid":false,"given":"Yaron","family":"Shoham","sequence":"additional","affiliation":[{"name":"Hand Unit, Plastic and Reconstructive Surgery, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amiram","family":"Sagi","sequence":"additional","affiliation":[{"name":"Hand Unit, Plastic and Reconstructive Surgery, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8709-3112","authenticated-orcid":false,"given":"Anat","family":"Reiner Benaim","sequence":"additional","affiliation":[{"name":"Department of Public Health Epidemiology, Biostatistics and Community Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eldad","family":"Silberstein","sequence":"additional","affiliation":[{"name":"Hand Unit, Plastic and Reconstructive Surgery, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva P.O. Box 151, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"ref_1","first-page":"e7333","article-title":"Carpal tunnel syndrome: A review of literature","volume":"12","author":"Genova","year":"2020","journal-title":"Cureus"},{"key":"ref_2","unstructured":"(2024, June 14). Carpal Tunnel Syndrome: Treatment and Prognosis. Available online: https:\/\/www-uptodate-com.bengurionu.idm.oclc.org\/contents\/carpal-tunnel-syndrome-treatment-and-prognosis."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S1474-4422(16)30231-9","article-title":"Carpal tunnel syndrome: Clinical features, diagnosis, and management","volume":"15","author":"Padua","year":"2016","journal-title":"Lancet Neurol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"6","DOI":"10.5312\/wjo.v14.i1.6","article-title":"Update on surgical procedures for carpal tunnel syndrome: What is the current evidence and practice? What are the future research directions?","volume":"14","author":"Pace","year":"2023","journal-title":"World J. 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J."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s11552-012-9429-x","article-title":"Long-term outcomes of carpal tunnel release: A critical review of the literature","volume":"7","author":"Louie","year":"2012","journal-title":"Hand"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Conzen, C., Conzen, M., R\u00fcbsamen, N., and Mikolajczyk, R. (2016). Predictors of the patient-centered outcomes of surgical carpal tunnel release\u2013a prospective cohort study. BMC Musculoskelet. Disord., 17.","DOI":"10.1186\/s12891-016-1046-3"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00701-019-03839-y","article-title":"Long-term outcome after carpal tunnel release and identification of prognostic factors","volume":"161","author":"Meulstee","year":"2019","journal-title":"Acta Neurochir."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/j.apmr.2017.04.024","article-title":"Effectiveness of surgical and postsurgical interventions for carpal tunnel syndrome\u2014A systematic review","volume":"99","author":"Huisstede","year":"2018","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Alimohammadi, E., Bagheri, S.R., Hadidi, H., Rizevandi, P., and Abdi, A. (2020). Carpal tunnel surgery: Predictors of clinical outcomes and patients\u2019 satisfaction. BMC Musculoskelet. 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