{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:32:25Z","timestamp":1791401545475,"version":"4.3.3"},"reference-count":37,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior\u2014Brasil (CAPES)","award":["001"],"award-info":[{"award-number":["001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Chronic kidney disease (CKD) can impair activities of daily living (ADL), reducing quality of life. The influence of biopsychosocial factors on ADL limitations among CKD patients remains unclear. This study aims to investigate associations between these factors and ADL limitations among CKD patients in the Brazilian population. We analyzed data from 839 individuals diagnosed with CKD obtained from the National Health Survey. The outcome was the presence or absence of limitations in ADL caused by CKD. Biopsychosocial factors included clinical and health status, self-perceived behavior, contextual social support, lifestyle, and household characteristics. Cox regression was employed to adjust interactions between these factors, with the prevalence ratio used as a measure of effect (\u03b1 \u2264 5%). From the analyzed sample, 373 CKD patients (40.7%; 95% CI: 35.4\u201346.1%) reported experiencing limitations in ADL. These limitations were associated with individual and contextual factors, including lack of private health insurance, residing in a rural area, poorer self-perceived health, presence of depressive symptoms, physical\/mental disabilities, use of medications, and undergoing hemodialysis. Limitations in ADL among individuals with CKD are associated with biopsychosocial factors in the Brazilian population, emphasizing the necessity for public policies that support enhanced therapeutic management and address behavioral health.<\/jats:p>","DOI":"10.3390\/ijerph21121680","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T08:17:00Z","timestamp":1734423420000},"page":"1680","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Biopsychosocial Factors Associated with Activities of Daily Living Limitations in Chronic Kidney Disease Patients: Insights from the Brazilian Population"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4708-1499","authenticated-orcid":false,"given":"Hellen de Carvalho","family":"Lima","sequence":"first","affiliation":[{"name":"Department of Medicine, Federal University of Vale do S\u00e3o Francisco, Paulo Afonso 56304-917, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joubert Vitor de Souto","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Federal University of Rio Grande do Norte, Natal 59078-900, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2967-9486","authenticated-orcid":false,"given":"Adson Arag\u00e3o de Ara\u00fajo","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal University of Vale do S\u00e3o Francisco, Paulo Afonso 56304-917, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Limeira","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Federal University of Rio Grande do Norte, Natal 59078-900, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8829-8141","authenticated-orcid":false,"given":"Adirlene Pontes de Oliveira","family":"Ten\u00f3rio","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal University of Vale do S\u00e3o Francisco, Paulo Afonso 56304-917, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3719-4131","authenticated-orcid":false,"given":"Matheus Rodrigues","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal University of Vale do S\u00e3o Francisco, Paulo Afonso 56304-917, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4092-4115","authenticated-orcid":false,"given":"Thais Sousa Rodrigues","family":"Guedes","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Federal University of Rio Grande do Norte, Natal 59078-900, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achilles de Souza","family":"Andrade","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geronimo Jos\u00e9 Bouzas","family":"Sanchis","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Federal University of Rio Grande do Norte, Natal 59078-900, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7227-1075","authenticated-orcid":false,"given":"Rodrigo","family":"Pegado","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Federal University of Rio Grande do Norte, Natal 59078-900, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9679-5287","authenticated-orcid":false,"given":"Johnnatas Mikael","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal University of Vale do S\u00e3o Francisco, Paulo Afonso 56304-917, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello Barbosa Otoni Gon\u00e7alves","family":"Guedes","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Federal University of Rio Grande do Norte, Natal 59078-900, RN, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,17]]},"reference":[{"key":"ref_1","unstructured":"Kidney Disease: Improving Global Outcomes CKD Work Group (2012). KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. Suppl., 3, S1\u2013S150."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group (2024). KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int., 105, S117\u2013S314.","DOI":"10.1016\/j.kint.2023.10.018"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.kint.2023.05.013","article-title":"Conference Participants. Trends and perspectives for improving quality of chronic kidney disease care: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference","volume":"104","author":"Eckardt","year":"2023","journal-title":"Kidney Int."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Kao, H.Y., Chang, C.C., Chang, C.F., Chen, Y.C., Cheewakriangkrai, C., and Tu, Y.L. (2022). Associations between Sex and Risk Factors for Predicting Chronic Kidney Disease. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19031219"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"382","DOI":"10.23876\/j.krcp.18.0128","article-title":"Impact of chronic kidney disease on mortality: A nationwide cohort study","volume":"38","author":"Kim","year":"2019","journal-title":"Kidney Res. Clin. Pract."},{"key":"ref_6","unstructured":"GBD Chronic Kidney Disease Collaboration (2020). Global, regional, and national burden of chronic kidney disease, 1990\u20132017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet, 395, 709\u2013733."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1159\/000538068","article-title":"Chronic Kidney Disease in Brazil: Current Status and Recommended Improvements","volume":"10","author":"Bauer","year":"2024","journal-title":"Kidney Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e29702","DOI":"10.1097\/MD.0000000000029702","article-title":"Temporal trend of mortality and hospitalization for chronic kidney disease in adults from Northern Brazil","volume":"10","author":"Rodrigues","year":"2022","journal-title":"Medicine"},{"key":"ref_9","first-page":"e2021385","article-title":"Self-report of medical diagnosis of chronic kidney disease: Prevalence and characteristics in the Brazilian adult population, National Health Survey 2013 and 2019","volume":"31","author":"Szwarcwald","year":"2022","journal-title":"Epidemiol. Serv. Saude"},{"key":"ref_10","first-page":"e20230062","article-title":"Brazilian Dialysis Survey 2022","volume":"46","author":"Nerbass","year":"2024","journal-title":"J. Bras. Nefrol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/S0140-6736(16)32064-5","article-title":"Chronic kidney disease","volume":"389","author":"Webster","year":"2017","journal-title":"Lancet"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1136\/jech-2015-205834","article-title":"Chronic kidney disease among adult participants of the ELSA-Brasil cohort: Association with race and socioeconomic position","volume":"70","author":"Barreto","year":"2016","journal-title":"J. Epidemiol. Community Health"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1007\/s40520-023-02510-y","article-title":"Epidemiology of chronic kidney disease in older indigenous peoples of Brazil: Findings from a cross-sectional survey","volume":"35","author":"Gomes","year":"2023","journal-title":"Aging Clin. Exp. Res."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Flythe, J.E., Karlsson, N., Sundgren, A., Cordero, P., Grandinetti, A., Cremisi, H., and Ryd\u00e9n, A. (2021). Development of a preliminary conceptual model of the patient experience of chronic kidney disease: A targeted literature review and analysis. BMC Nephrol., 22.","DOI":"10.1186\/s12882-021-02440-9"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1007\/s11255-020-02559-y","article-title":"Mild chronic kidney disease and its relation to functional disability in Korean elderly population","volume":"52","author":"Park","year":"2020","journal-title":"Int. Urol. Nephrol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"609","DOI":"10.2147\/CIA.S249137","article-title":"Main Risk Factors Related to Activities of Daily Living in Non-Dialysis Patients with Chronic Kidney Disease Stage 3-5: A Case-Control Study","volume":"15","author":"Chang","year":"2020","journal-title":"Clin. Interv. Aging"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5935\/0101-2800.20140001","article-title":"Chronic kidney disease and the aging population","volume":"36","author":"Tonelli","year":"2014","journal-title":"J. Bras. Nefrol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Aune, D., Sun, X., Nie, J., Huang, W., Liao, B., and Wang, Y. (2022). Self-reported chronic kidney disease and the risk of all-cause and cause-specific mortality: Outcome-wide association study of 54 causes of death in the National Health Interview Survey. BMC Nephrol., 23.","DOI":"10.1186\/s12882-022-02771-1"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1590\/1413-81232015203.16182014","article-title":"Differentials in risk factors for chronic non-communicable diseases from the race\/color standpoint","volume":"20","author":"Malta","year":"2015","journal-title":"Cien. Saude Coletiva"},{"key":"ref_20","unstructured":"Lima, J.F. (2012). O Significado da Viv\u00eancia do Tratamento Hemodial\u00edtico para Indiv\u00edduos Provenientes do Contexto Rural. [Master\u2019s Dissertation, Universidade Federal de Pelotas]."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"e00213816","DOI":"10.1590\/0102-311x00213816","article-title":"Desigualdade no acesso \u00e0 sa\u00fade entre as \u00e1reas urbanas e rurais do Brasil: Uma decomposi\u00e7\u00e3o de fatores entre 1998 a 2008","volume":"34","author":"Arruda","year":"2018","journal-title":"Cad. Saude Publica"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1590\/S0101-28002012000200002","article-title":"Ades\u00e3o ao tratamento farmacol\u00f3gico de pacientes em hemodi\u00e1lise","volume":"34","author":"Sgnaolin","year":"2012","journal-title":"J. Bras. Nefrol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1590\/1413-81232018245.04332019","article-title":"Engaging people with chronic kidney disease in their own care: An integrative review","volume":"24","author":"Almeida","year":"2019","journal-title":"Cien. Saude Coletiva"},{"key":"ref_24","first-page":"187","article-title":"As principais complica\u00e7\u00f5es apresentadas pelos pacientes renais cr\u00f4nicos durante as sess\u00f5es de hemodi\u00e1lise","volume":"8","author":"Terra","year":"2010","journal-title":"Rev. Bras. Clin. Med."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1590\/2175-8239-jbn-2018-0152","article-title":"Quality of life of individuals with chronic kidney disease on dialysis","volume":"41","author":"Jesus","year":"2019","journal-title":"J. Bras. Nefrol."},{"key":"ref_26","first-page":"591","article-title":"Changes in occupational performance of individuals with chronic kidney disease undergoing peritoneal dialysis","volume":"6","author":"Moraes","year":"2018","journal-title":"REFACS"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1080\/0886022X.2019.1625788","article-title":"Comparison of peritoneal dialysis with hemodialysis on survival of diabetic patients with end-stage kidney disease: A meta-analysis of cohort studies","volume":"41","author":"Xue","year":"2019","journal-title":"Ren. Fail."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3747\/pdi.2017.00236","article-title":"The Effect of Peritoneal Dialysis on Labor Market Outcomes Compared with Institutional Hemodialysis","volume":"39","author":"Ghani","year":"2019","journal-title":"Perit. Dial. Int."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1177\/1357633X18784417","article-title":"Impact of remote biometric monitoring on cost and hospitalization outcomes in peritoneal dialysis","volume":"25","author":"Lew","year":"2019","journal-title":"J. Telemed. Telecare"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.2215\/CJN.05680518","article-title":"Medicare\u2019s new prospective payment system on facility provision of peritoneal dialysis","volume":"13","author":"Wang","year":"2018","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.genhosppsych.2013.05.006","article-title":"Anxiety and depressive disorders in dialysis patients: Association to health-related quality of life and mortality","volume":"35","author":"Preljevic","year":"2013","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"e023258","DOI":"10.1136\/bmjopen-2018-023258","article-title":"Impact of the great recession on self-perceived health in Spain: A longitudinal study with individual data","volume":"9","author":"Saez","year":"2019","journal-title":"BMJ Open"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Inuzuka, S., Jardim, P.C.V., Abrahams-Gessel, S., Souza, L.G., Rezende, A.C., and Perillo, N.B. (2018). Self-rated health status and illiteracy as death predictors in a Brazilian cohort. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0200501"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"216","DOI":"10.15343\/0104-7809.2013372216220","article-title":"A import\u00e2ncia da Sa\u00fade Suplementar na demanda da presta\u00e7\u00e3o dos servi\u00e7os assistenciais no Brasil","volume":"37","author":"Ziroldo","year":"2013","journal-title":"Mundo Saude"},{"key":"ref_35","first-page":"302","article-title":"Survival in hemodialysis in Brazil according to the source of payment: Public Healthcare System (SUS) versus private insurance","volume":"45","author":"Barra","year":"2023","journal-title":"Braz. J. Nephrol."},{"key":"ref_36","first-page":"519","article-title":"Smoking as risk factor for chronic kidney disease: Systematic review","volume":"36","author":"Elihimas","year":"2014","journal-title":"J. Bras. Nefrol."},{"key":"ref_37","first-page":"e3028","article-title":"Social construction of the experience of living with chronic kidney disease","volume":"26","year":"2018","journal-title":"Rev. Lat. Am. Enfermagem"}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/12\/1680\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:53:57Z","timestamp":1760115237000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/21\/12\/1680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,17]]},"references-count":37,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["ijerph21121680"],"URL":"https:\/\/doi.org\/10.3390\/ijerph21121680","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,17]]}}}