{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T21:31:20Z","timestamp":1779139880532,"version":"3.51.4"},"reference-count":52,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior\u2014Brazil (CAPES)","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Evidence indicates a difference between men and women in oral anticoagulation control, but the results were discrepant. This study investigated the association of sex with oral anticoagulation control in patients on warfarin assisted by anticoagulation clinics (ACs) in Brazil. The cross-sectional study included patients on warfarin recruited at three public ACs in southeast Brazil (2014\u20132015). The quality of oral anticoagulation was estimated by the time in therapeutic range (TTR). Univariable and multivariable linear regression models were built to examine the association of sociodemographic, behavior, clinical, and drug therapy variables with TTR. Overall, 801 participants were studied (455; 56.8% women), with a mean age of 65.0 (13.4) years. The female sex was associated with lower TTR than the male sex (Beta (95% CI) = \u221217.01 (\u221230.25; \u22123.76), p = 0.012), however, this difference decreased with increasing age, becoming null after age 60. Smoking patients had a lower TTR than non-smokers (\u22125.18 (\u221210.02; \u22120.34), p = 0.036). The results showed that the association of sex with oral anticoagulation control is dependent on age. Women have lower TTR than men, but this difference is null in older patients. Knowledge of these factors may be useful for developing strategies to improve care for these patients.<\/jats:p>","DOI":"10.3390\/ijerph22010065","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T09:17:02Z","timestamp":1736155022000},"page":"65","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Quality of Oral Anticoagulation Control with Warfarin According to Sex: A Cross-Sectional Study"],"prefix":"10.3390","volume":"22","author":[{"given":"Catiane Costa","family":"Viana","sequence":"first","affiliation":[{"name":"Faculdade de Farm\u00e1cia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4226-6926","authenticated-orcid":false,"given":"Marcus Fernando da Silva","family":"Praxedes","sequence":"additional","affiliation":[{"name":"Faculdade de Farm\u00e1cia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil"},{"name":"Centro de Ci\u00eancias da Sa\u00fade, Universidade Federal do Rec\u00f4ncavo da Bahia, Santo Ant\u00f4nio de Jesus 44430-622, Bahia, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8794-5725","authenticated-orcid":false,"given":"Mauro Henrique Nogueira Guimar\u00e3es de","family":"Abreu","sequence":"additional","affiliation":[{"name":"Faculdade de Odontologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waleska Jaclyn Freitas Nunes de","family":"Sousa","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil"},{"name":"Hospital das Cl\u00ednicas, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e1ssia Rodrigues Lima","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil"},{"name":"Hospital das Cl\u00ednicas, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Em\u00edlio Itamar de Freitas","family":"Campos","sequence":"additional","affiliation":[{"name":"Faculdade de Farm\u00e1cia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3146-0793","authenticated-orcid":false,"given":"Jos\u00e9 Luiz Padilha da","family":"Silva","sequence":"additional","affiliation":[{"name":"Departamento de Estat\u00edstica, Universidade Federal do Paran\u00e1, Curitiba 81531-980, Paran\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5211-411X","authenticated-orcid":false,"given":"Maria Auxiliadora Parreiras","family":"Martins","sequence":"additional","affiliation":[{"name":"Faculdade de Farm\u00e1cia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil"},{"name":"Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil"},{"name":"Hospital das Cl\u00ednicas, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil"},{"name":"Hospital Risoleta Tolentino Neves, Belo Horizonte 31744-012, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Praxedes, M.F.S., da Silva, J.L.P., da Cruz, A.J.A., Viana, C.C., Barbosa, H.C., Guimar\u00e3es, N.S., and Martins, M.A.P. 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