{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:07:32Z","timestamp":1789578452584,"version":"build-2803163510"},"reference-count":51,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)","award":["313299\/2018-8"],"award-info":[{"award-number":["313299\/2018-8"]}]},{"name":"Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)","award":["310241\/2022-7"],"award-info":[{"award-number":["310241\/2022-7"]}]},{"name":"Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)","award":["202210267000625"],"award-info":[{"award-number":["202210267000625"]}]},{"name":"Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (local acronym CNPq)","award":["313299\/2018-8"],"award-info":[{"award-number":["313299\/2018-8"]}]},{"name":"Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (local acronym CNPq)","award":["310241\/2022-7"],"award-info":[{"award-number":["310241\/2022-7"]}]},{"name":"Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (local acronym CNPq)","award":["202210267000625"],"award-info":[{"award-number":["202210267000625"]}]},{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa do Estado de Goi\u00e1s (FAPEG)","award":["313299\/2018-8"],"award-info":[{"award-number":["313299\/2018-8"]}]},{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa do Estado de Goi\u00e1s (FAPEG)","award":["310241\/2022-7"],"award-info":[{"award-number":["310241\/2022-7"]}]},{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa do Estado de Goi\u00e1s (FAPEG)","award":["202210267000625"],"award-info":[{"award-number":["202210267000625"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: COVID-19 mainly affects the respiratory system, although its manifestations are multisystemic. We are increasingly recognizing complications that present after the acute phase, which are associated with impaired functional status and health-related quality of life (HRQoL). The objective was to assess the functional status and HRQoL of patients with post-COVID-19. Methods: This was a cross-sectional study involving individuals affected by COVID-19 who had persistent symptoms for one month after the acute phase of the disease. Functional status was measured with the six-minute walk test (6MWT), the Fatigue Severity Scale (FSS), the Medical Research Council (MRC) Dyspnea Scale, and the Post-COVID-19 Functional Status Scale (PCFS). HRQoL was confirmed with the Short-Form Health Survey 36 (SF-36). Results: We included 123 patients; 73 (59.35%) were male, with a mean age of 49.17 \u00b1 13.48 years and a body mass index of 31.02 \u00b1 6.56 stratified into three groups: the not-recovered group (NRG = 23), the ward-recovered group (WHG = 60), and the intensive-care-unit group (ICUG = 40). The main symptoms were muscle weakness (74.17%) and dyspnea (68.33%). The predicted distances for the 6MWT were missed by 12.83% by the GNR group, 20.21% by the GNR group, and 28.82% by the UGCI group. The MRC dyspnea scale had a mean value of less than 3, and the FSS scale had a mean value of over 4, indicating considerable fatigue. In the PCFS scale, a significant difference was observed (p &lt; 0.0005), while in the SF-36, all HRQoL domains were compromised. Conclusion: Post-COVID-19 patients involved in this study showed a significant decline in functional status and an impairment of HRQoL.<\/jats:p>","DOI":"10.3390\/ijerph22030338","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T12:01:17Z","timestamp":1740484877000},"page":"338","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5302-1388","authenticated-orcid":false,"given":"Miri\u00e3 C.","family":"Oliveira","sequence":"first","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa R.","family":"Alves","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"},{"name":"Health Sciences Graduate Program, Faculty of Medical Sciences of Santa Casa de S\u00e3o Paulo, S\u00e3o Paulo 01224-001, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1801-8172","authenticated-orcid":false,"given":"Juliana M. P.","family":"Soares","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shayra K. A.","family":"Souza","sequence":"additional","affiliation":[{"name":"Scientific Initiation Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna M. R.","family":"Silva","sequence":"additional","affiliation":[{"name":"Scientific Initiation Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano L.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos H. M.","family":"Silva","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"},{"name":"Health Sciences Graduate Program, Faculty of Medical Sciences of Santa Casa de S\u00e3o Paulo, S\u00e3o Paulo 01224-001, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia S.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6379-1143","authenticated-orcid":false,"given":"Rodolfo P.","family":"Vieira","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deise A. A. P.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irans\u00e9","family":"Oliveira-Silva","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo F.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0110-7710","authenticated-orcid":false,"given":"Luciana M. M.","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Rehabilitation Sciences, Graduate Program, Nove de Julho University (UNINOVE), S\u00e3o Paulo 01504-001, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7804-7517","authenticated-orcid":false,"given":"Vinicius","family":"Maldaner","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9909-4403","authenticated-orcid":false,"given":"Dante B.","family":"Santos","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4799-0385","authenticated-orcid":false,"given":"Renata K.","family":"Palma","sequence":"additional","affiliation":[{"name":"Human Movement and Rehabilitation Graduate Program, Evangelical University of Goi\u00e1s (UniEVANGELICA), An\u00e1polis 75083-515, GO, Brazil"},{"name":"Facultad de Ciencias de la Salud de Manresa, Universitat de Vic-Universitat Central de Catalunya (UVic-UCC), 08242 Manresa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio R.","family":"Nacif","sequence":"additional","affiliation":[{"name":"Health Sciences Graduate Program, Institute of Medical Assistance to State Public Servants (IAMSPE), Av. Ibirapuera, 981, S\u00e3o Paulo 04029-000, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9506-2233","authenticated-orcid":false,"given":"Giuseppe","family":"Insalaco","sequence":"additional","affiliation":[{"name":"Institute of Translational Pharmacology, National Research Council of Italy (CNR), 90146 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3852-9415","authenticated-orcid":false,"given":"Lu\u00eds V. 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