{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T06:55:05Z","timestamp":1784098505273,"version":"3.55.0"},"reference-count":37,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Introduction: One of the global strategies for the elimination of schistosomiasis is by Mass Drug Administration (MDA) of a single oral dose of praziquantel (40 mg\/kg) without a prior individual diagnosis, with a target of &gt;75% treatment coverage among school-aged children. This study was conducted to determine the endemicity of schistosomiasis among school-aged children and adults in Abuja, Nigeria. Methods: A total of 1370 participants were recruited, which consisted of 667 (48.67%) males and 703 (51.31%) females. Urine and stool specimens were collected from each participant and analyzed using standard procedures. Results: The overall prevalence of schistosomiasis was 27.5% in this study with Abuja Municipal having the highest prevalence of 49%, while the least (6.1%) was reported in Bwari LAC. The prevalence of schistosomiasis significantly differs (p &lt; 0.05) between the area councils. The location of communities significantly affected the prevalence of schistosomiasis in Abaji, AMAC, and Gwagwalada LACs (p &lt; 0.005). The Schistosoma recovered in this study were S. haematobium and S. mansoni. The prevalence of schistosomiasis increased from the baseline of 21.1% to 49% in Gwagwalada LAC. Gender significantly affected the prevalence of schistosomiasis as more males were infected (33.1%) than their female counterparts (22.2%) (p &lt; 0.05). The prevalence of schistosomiasis was 31% and 23.9% among SAC and adults, respectively. The participants\u2019 activities in the river significantly affected the prevalence of schistosomiasis in this study (p &lt; 0.05). Conclusions: The clamour for urgent government and non-government intervention through alternate sources of water like boreholes or pipe-borne water, as well as implementing a behavioural change campaign across the communities to prevent the recurrence, are advocated.<\/jats:p>","DOI":"10.3390\/ijerph22050672","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T11:44:52Z","timestamp":1745495092000},"page":"672","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Impact of Praziquantel Mass Drug Administration on Schistosomiasis: A Comparison of Prevalence and Risk Factors Between Treated School Aged Children and Untreated Adults in Abuja, Nigeria"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5392-3819","authenticated-orcid":false,"given":"Solomon M.","family":"Jacob","sequence":"first","affiliation":[{"name":"Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria"},{"name":"Department of Public Health, Federal Ministry of Health, P.M.B. 083, Garki, Abuja 900108, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie Y.","family":"Akinbo","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology Diagnosis, Northwestern Memorial Hospital, Chicago, IL 60611, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinola S.","family":"Oluwole","sequence":"additional","affiliation":[{"name":"Sightsavers Country Office, Abuja 900271, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Temitope","family":"Agbana","sequence":"additional","affiliation":[{"name":"AiDx Medical Bv, 2641 KM Pijnacker, The Netherlands"},{"name":"Sustainable Design Engineering, Delft University of Technology, 2628 CE Delft, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainab","family":"Omoruyi","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Okungbowa","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4007-2282","authenticated-orcid":false,"given":"Jan-Carel","family":"Diehl","sequence":"additional","affiliation":[{"name":"Sustainable Design Engineering, Delft University of Technology, 2628 CE Delft, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrick O.","family":"Akinbo","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41572-018-0013-8","article-title":"Schistosomiasis","volume":"4","author":"McManus","year":"2018","journal-title":"Nat. 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