{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:20:37Z","timestamp":1760059237199,"version":"build-2065373602"},"reference-count":58,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T00:00:00Z","timestamp":1748649600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Research Council (ERC)","award":["647000"],"award-info":[{"award-number":["647000"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Several epidemiological studies have documented associations between air pollution exposure and cardiovascular responses, including adverse effects of air pollutants on blood pressure (BP). However, previous studies only considered the effect of specific air pollutants on resting BP, and did not sufficiently consider the independent effects of various air pollution species as well as their overall mixture effect. We addressed this gap in our MobiliSense sensor-based study among 273 participants living in the Grand Paris region. Participants wore personal monitors to assess personal exposure to particles [black carbon and particulate matter smaller than 2.5 \u03bcm in diameter (PM2.5)] and gaseous pollutants [ozone (O3), nitrogen monoxide (NO), carbon monoxide (CO), and nitrogen dioxide (NO2)] along with noise exposure. Participants were asked to measure their blood pressure (BP) at rest in the mornings and evenings for three days. Multilevel models with a random intercept at the individual level explored the relationship between air pollution exposure (averaged over the day) and change in resting BP from morning to evening. We also used the quantile G-computation method to estimate the joint effect of the mixture of targeted air pollutants on resting BP. Sensitivity analyses examined the associations between air pollution exposure averaged at different temporal scales before evening BP measurements and the outcome. A quantile increase in the mixture of air pollutants (PM2.5, NO2, NO, CO, and O3) over the day did not affect changes in systolic BP [\u22120.33 mmHg (95% CI: \u22123.31, 2.65)] and diastolic BP [\u22120.53 mmHg (95% CI: \u22122.66, 1.60)] from morning to evening. When shorter time exposure windows were considered (from a few minutes to a few hours), both NO and the mixture showed positive associations with the morning-to-evening DBP change in only some of the models. Future studies with sufficient repeated BP measurements for more participants should test the association at varying temporal scales (minutes to days) to better understand how air pollution exposure influences resting BP.<\/jats:p>","DOI":"10.3390\/ijerph22060872","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T03:57:18Z","timestamp":1748923038000},"page":"872","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exposure to Air Pollution and Changes in Resting Blood Pressure from Morning to Evening: The MobiliSense Study"],"prefix":"10.3390","volume":"22","author":[{"given":"Lisa","family":"Sekarimunda","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique IPLESP, Nemesis Team, Facult\u00e9 de M\u00e9decine Saint-Antoine, 27 rue Chaligny, 75012 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clelie","family":"Dureau","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique IPLESP, Nemesis Team, Facult\u00e9 de M\u00e9decine Saint-Antoine, 27 rue Chaligny, 75012 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basile","family":"Chaix","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique IPLESP, Nemesis Team, Facult\u00e9 de M\u00e9decine Saint-Antoine, 27 rue Chaligny, 75012 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8937-7933","authenticated-orcid":false,"given":"Sanjeev","family":"Bista","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique IPLESP, Nemesis Team, Facult\u00e9 de M\u00e9decine Saint-Antoine, 27 rue Chaligny, 75012 Paris, France"},{"name":"Centre de Recherche en Sant\u00e9 Publique, Universit\u00e9 de Montr\u00e9al, 7101 Avenue du Parc, Montreal, QC H3N 1X9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/000331977502600101","article-title":"Role of Blood Pressure in Cardiovascular Disease: The Framingham Study","volume":"26","author":"Kannel","year":"1975","journal-title":"Angiology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0140-6736(23)00733-X","article-title":"Relationship between clinic and ambulatory blood pressure and mortality: An observational cohort study in 59,124 patients","volume":"401","author":"Staplin","year":"2023","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1161\/HYPERTENSIONAHA.108.123877","article-title":"Acute Effects of Ambient Particulate Matter on Blood Pressure: Differential Effects Across Urban Communities","volume":"53","author":"Dvonch","year":"2009","journal-title":"Hypertension"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/S0140-6736(02)11911-8","article-title":"Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies","volume":"360","author":"Lewington","year":"2002","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1093\/eurheartj\/ehy801","article-title":"Reconsidering the cut-off diastolic blood pressure for predicting cardiovascular events: A nationwide population-based study from Korea","volume":"40","author":"Choi","year":"2019","journal-title":"Eur. 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