{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:36:02Z","timestamp":1760060162693,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Background: The COVID-19 pandemic presented unprecedented challenges for people with multiple sclerosis (PwMS) in Oman, necessitating targeted healthcare planning and patient support. This study aimed to investigate the impact of COVID-19 on MS management and disease course, incidence, and outcomes of COVID-19, psychosocial and mental health effects of the pandemic, and demographic and clinical predictors of the effects related to COVID-19 among Omani PwMS. (2) Methods: This cross-sectional study was conducted from January to April 2021. Adult (18\u201360 years) Omani PwMS completed a structured interview along with the Expanded Disability Status Scale (EDSS) and World Health Organization Well-being Index (WHO-5). Clinical data on relapses and disease-modifying therapies and adherence were analyzed. The data was statistically analyzed. (3) Results: Of 104 PwMS (73.1% female), 22.1% contracted COVID-19, with fatigue being the most reported symptom (87%). Female sex (p = 0.042), younger age (18\u201334 vs. 35\u201345 years; p = 0.014), diagnosis of COVID-19 (p = 0.037), and low current mental well-being scores (p = 0.021) predicted greater COVID-19-related effects. (4) Conclusion: These findings highlight the need to study the mental resilience of this subgroup of PwMS and provide them with targeted support during crises.<\/jats:p>","DOI":"10.3390\/ijerph22081236","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T08:09:35Z","timestamp":1754640575000},"page":"1236","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychosocial Impact of the COVID-19 Pandemic Among Omanis with Multiple Sclerosis: Single Tertiary Center Experience"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5376-2316","authenticated-orcid":false,"given":"Jihad Yaqoob Ali","family":"Al Kharbooshi","sequence":"first","affiliation":[{"name":"Department of Clinical Neurological Sciences, Western University, London Health Sciences Center, London, ON N6A 3K7, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2851-8157","authenticated-orcid":false,"given":"Abdullah","family":"Al-Asmi","sequence":"additional","affiliation":[{"name":"Neurology Unit, Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat 123, Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4887-9088","authenticated-orcid":false,"given":"Ronald","family":"Wesonga","sequence":"additional","affiliation":[{"name":"Department of Statistics, College of Science, Sultan Qaboos University, Muscat 123, Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9858-5582","authenticated-orcid":false,"given":"Samir","family":"Al Adawi","sequence":"additional","affiliation":[{"name":"Department of Behavioral Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat 123, Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2636-5596","authenticated-orcid":false,"given":"Amal S. S.","family":"Al-Fahdi","sequence":"additional","affiliation":[{"name":"Psychosocial Unit, Department of Holistic Care, Sultan Qaboos Comprehensive Cancer Care and Research Center, University Medical City, Muscat 123, Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,7]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2020, October 03). Coronavirus Disease (COVID-19). Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/coronavirus-disease-(covid-19)."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"103034","DOI":"10.1016\/j.msard.2021.103034","article-title":"Epidemiology of multiple sclerosis in the Sultanate of Oman: A hospital-based study","volume":"53","author":"Nandhagopal","year":"2021","journal-title":"Mult. Scler. Relat. 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