{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:42:14Z","timestamp":1791996134682,"version":"4.4.0"},"reference-count":38,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior\u2014Brasil","award":["001"],"award-info":[{"award-number":["001"]}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Aging is associated with changes in body composition that lead to low-grade chronic inflammation, compromising the health of the elderly. This condition can be mitigated by resistance training (RT) and vitamin D supplementation, promoting the health of this population. This study aimed to investigate the effects of 12 weeks of RT combined with vitamin D supplementation on body composition, muscle strength, and inflammatory status in older adults. A total of 26 participants were randomly assigned to an Experimental Group (EG: n = 12; 11 Female; 70.6 \u00b1 4.7 years; RT + 2000 IU\/day of vitamin D) and a Control Group (EG: n = 14; 11 Female; 69.6 \u00b1 4.6 years; RT + placebo). Both groups performed the same RT program (8 exercises; 2 sets; 10 RM, twice per week). Before and after the intervention, participants were assessed using DEXA, strength tests (sit-to-stand test and handgrip strength), and serum biomarkers (IL-6, TNF-\u03b1, 25(OH)D). Both groups showed significant strength gains, particularly in the lower limbs (p &lt; 0.05 for all tests and groups), with no between-group differences in body composition or inflammatory markers (p &gt; 0.05 for all tests and groups). A time \u00d7 group interaction was observed for IL-6 (p = 0.03), with a slight reduction in the EG and an increase in the CG, although post-intervention differences were not statistically significant (p = 0.49). No statistically significant between-group difference in 25(OH)D change (p = 0.11). These findings suggest that vitamin D supplementation at the tested dose did not enhance adaptations to resistance training in older adults with normal baseline vitamin D levels. Further studies are warranted to explore potential benefits in deficient populations and with alternative dosing strategies.<\/jats:p>","DOI":"10.3390\/ijerph22111695","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T10:35:31Z","timestamp":1762770931000},"page":"1695","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Resistance Training Combined with Vitamin D Supplementation on Health-Related Variables in the Elderly: Muscle Strength, Body Composition, and Inflammatory Status"],"prefix":"10.3390","volume":"22","author":[{"given":"Lorena Cristina Ribeiro da","family":"Rosa","sequence":"first","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2463-1280","authenticated-orcid":false,"given":"Paulo de Tarso Veras","family":"Farinatti","sequence":"additional","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3134-4271","authenticated-orcid":false,"given":"Maria Izabel Ferreira","family":"Batista","sequence":"additional","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilene Ribeiro Santiago Navarro","family":"Machado","sequence":"additional","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor Hugo Silva de","family":"Jesus","sequence":"additional","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weslen do Nascimento","family":"Dantas","sequence":"additional","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2494-6912","authenticated-orcid":false,"given":"Patr\u00edcia Maria Louren\u00e7o","family":"Dutra","sequence":"additional","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0617-0521","authenticated-orcid":false,"given":"N\u00e1dia Souza Lima da","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Individual Sports, Institute of Physical Education and Sports, Postraduate Program in Exercise and Sport Science, Maracan\u00e3 Campus, State University of Rio de Janeiro., Rio de Janeiro 20550-013, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"ref_1","first-page":"2454","article-title":"Effects of twenty-four weeks of resistance exercise training on body composition, bone mineral density, functional fitness and isokinetic muscle strength in obese older women: A randomized controlled trial","volume":"19","author":"Kim","year":"2022","journal-title":"Int. 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