{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:03:46Z","timestamp":1785405826483,"version":"3.56.0"},"reference-count":48,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Environ. Res. Public Health","IJERPH"],"abstract":"<jats:p>Glyphosate-based herbicides are widely used agricultural chemicals. Concerns regarding carcinogenicity, particularly non-Hodgkin lymphoma (NHL), persist. We conducted a systematic review and meta-analysis to better evaluate glyphosate exposure and NHL risk. MEDLINE and EMBASE were searched for eligible cohort, case\u2013control, and pooled studies. Risk of bias was assessed using recommended criteria. Random- and fixed-effects meta-analyses were performed, with sensitivity analyses addressing overlapping cohorts, hazard ratio inclusion, exposure definitions, and model overfitting. Evidence certainty was graded using GRADE. Ten primary datasets were analyzed. Ever-exposure was associated with an odds ratio of 1.11. Highest-exposure analyses demonstrated a significant association with NHL. Ever-exposure associations were modest, whereas a higher glyphosate exposure was consistently associated with an increased NHL risk. The findings were robust across sensitivity analyses.<\/jats:p>","DOI":"10.3390\/ijerph23081000","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:32:13Z","timestamp":1785403933000},"page":"1000","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Systematic Review and Meta-Analysis of Glyphosate-Based Herbicide Exposure and Risk of Non-Hodgkin Lymphoma"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3162-3935","authenticated-orcid":false,"given":"Joel J.","family":"Gagnier","sequence":"first","affiliation":[{"name":"Department of Epidemiology & Biostatistics, Western University, London, ON N6A 3K7, Canada"},{"name":"Department of Surgery, Western University, London, ON N6A 3K7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3097-6920","authenticated-orcid":false,"given":"John P.","family":"O\u2019Connor","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"ref_1","unstructured":"International Agency for Research on Cancer (2017). 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