{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:37:40Z","timestamp":1790861860549,"version":"4.1.0"},"reference-count":28,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2009,11,12]],"date-time":"2009-11-12T00:00:00Z","timestamp":1257984000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>We assess the influence of co-occurring psychiatric disorders on retention in 189 opioid dependent patients in a methadone maintenance treatment (MMT) and determine the incidence of psychiatric co-morbidity during an 18-month follow-up period. About 68.5 % were retained in the MMT. Neither co-occurring mental disorders (chi-square = 0.303, df = 1, p = 0.622) nor methadone doses [85 (88.9) vs. 79.2 (85) mg\/day, p = 0.672] were related to retention. In the follow-up period 19 new diagnoses were made, mainly major depression and antisocial and borderline personality disorders. Co-occurring psychiatric disorders should be assessed during MMT follow-up.<\/jats:p>","DOI":"10.3390\/ijerph6112822","type":"journal-article","created":{"date-parts":[[2009,11,12]],"date-time":"2009-11-12T10:48:29Z","timestamp":1258022909000},"page":"2822-2832","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Impact of Co-Occurring Psychiatric Disorders on Retention in a Methadone Maintenance Program: An 18-Month Follow-Up Study"],"prefix":"10.3390","volume":"6","author":[{"given":"M\u00f2nica","family":"Astals","sequence":"first","affiliation":[{"name":"Institute of Psychiatry and Addiction (IAPs), Hospital del Mar and Institut Municipal d\u2019Investigaci\u00f3 M\u00e8dica (IMIM), Hospital del Mar, Psg. Mar\u00edtim 25-29, E-08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"D\u00edaz","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry and Addiction (IAPs), Hospital del Mar and Institut Municipal d\u2019Investigaci\u00f3 M\u00e8dica (IMIM), Hospital del Mar, Psg. Mar\u00edtim 25-29, E-08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ant\u00f2nia","family":"Domingo-Salvany","sequence":"additional","affiliation":[{"name":"Research Programme in Epidemiology and Public Health, Institut Municipal d\u2019Investigaci\u00f3 M\u00e8dica (IMIM), Hospital del Mar, Doctor Aiguader 88, E-08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roc\u00edo","family":"Mart\u00edn-Santos","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry and Addiction (IAPs), Hospital del Mar and Institut Municipal d\u2019Investigaci\u00f3 M\u00e8dica (IMIM), Hospital del Mar, Psg. Mar\u00edtim 25-29, E-08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"Bulbena","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry and Addiction (IAPs), Hospital del Mar and Institut Municipal d\u2019Investigaci\u00f3 M\u00e8dica (IMIM), Hospital del Mar, Psg. Mar\u00edtim 25-29, E-08003 Barcelona, Spain"},{"name":"Department of Psychiatry, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Torrens","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry and Addiction (IAPs), Hospital del Mar and Institut Municipal d\u2019Investigaci\u00f3 M\u00e8dica (IMIM), Hospital del Mar, Psg. Mar\u00edtim 25-29, E-08003 Barcelona, Spain"},{"name":"Department of Psychiatry, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2009,11,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1046\/j.1360-0443.1998.9345157.x","article-title":"The efficacy of methadone maintenance interventions in reducing illicit opiate use, HIV risk behavior and criminality: a meta-analysis","volume":"93","author":"Marsch","year":"1998","journal-title":"Addiction"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.jsat.2005.02.007","article-title":"An overview of systematic reviews of the effectiveness of opiate maintenance therapies: available evidence to inform clinical practice and research","volume":"28","author":"Amato","year":"2005","journal-title":"J. Subst. 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