{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:27:06Z","timestamp":1760243226187,"version":"build-2065373602"},"reference-count":32,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T00:00:00Z","timestamp":1397520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Cadmium signifies a severe threat to crop productivity and green gram is  a notably iron sensitive plant which shows considerable variation towards cadmium stress. A gel-based proteomics analysis was performed with the roots of green gram exposed to iron and cadmium combined treatments. The resulting data show that twenty three proteins were down-regulated in iron-deprived roots either in the absence (\u2212Fe\/\u2212Cd) or presence  (\u2212Fe\/+Cd) of cadmium. These down-regulated proteins were however well expressed  in roots under iron sufficient conditions, even in the presence of cadmium (+Fe\/+Cd).  The functional classification of these proteins determined that 21% of the proteins are associated with nutrient metabolism. The other proteins in higher quantities are involved in either transcription or translation regulation, and the rest are involved in biosynthesis metabolism, antioxidant pathways, molecular chaperones and stress response. On the other hand, several protein spots were also absent in roots in response to iron deprivation either in absence (\u2212Fe\/\u2212Cd) or presence (\u2212Fe\/+Cd) of cadmium but were well expressed in the presence of iron (+Fe\/+Cd). Results suggest that green gram plants exposed to cadmium stress are able to change the nutrient metabolic balance in roots, but in the mean time regulate cadmium toxicity through iron supplements.<\/jats:p>","DOI":"10.3390\/ijms15046343","type":"journal-article","created":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T13:23:16Z","timestamp":1397568196000},"page":"6343-6355","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Cadmium Toxicity Induced Alterations in the Root Proteome of Green Gram in Contrasting Response towards Iron Supplement"],"prefix":"10.3390","volume":"15","author":[{"given":"Sowbiya","family":"Muneer","sequence":"first","affiliation":[{"name":"Department of Horticulture, College of Agricultural Life Sciences, Chonnam National University, 300 Young Bong-Dong Buk-Gu, Gwangju 500-757, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"Hakeem","sequence":"additional","affiliation":[{"name":"Faculty of Forestry, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rozi","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Faculty of Forestry, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Horticulture, College of Agricultural Life Sciences, Chonnam National University, 300 Young Bong-Dong Buk-Gu, Gwangju 500-757, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2014,4,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1104\/pp.111.190983","article-title":"Co-over expression FIT with AtbHLH38 or AtbHLH39 in Arabidopsis-Enhanced Cadmium Tolerance via Increased Cadmium Sequestration in Roots and Improved Iron Homeostasis of Shoots","volume":"158","author":"Wu","year":"2012","journal-title":"Plant Physiol"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1104\/pp.106.094474","article-title":"Iron Acquisition by phytosiderophores contributes to cadmium tolerance","volume":"143","author":"Meda","year":"2007","journal-title":"Plant Physiol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1016\/j.foodres.2013.06.024","article-title":"Transcriptomics analysis of iron deficiency related genes the legumes","volume":"54","author":"Santos","year":"2013","journal-title":"Food Res. 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