{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:36:07Z","timestamp":1790750167653,"version":"4.1.0"},"reference-count":27,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2018,11,28]],"date-time":"2018-11-28T00:00:00Z","timestamp":1543363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["16-14-10364"],"award-info":[{"award-number":["16-14-10364"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003443","name":"Ministry of Education and Science of the Russian Federation","doi-asserted-by":"publisher","award":["RFMEFI62117X0018"],"award-info":[{"award-number":["RFMEFI62117X0018"]}],"id":[{"id":"10.13039\/501100003443","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Fluorogens are an attractive type of dye for imaging applications, eliminating time-consuming washout steps from staining protocols. With just a handful of reported fluorogen-protein pairs, mostly in the green region of spectra, there is a need for the expansion of their spectral range. Still, the origins of solvatochromic and fluorogenic properties of the chromophores suitable for live-cell imaging are poorly understood. Here we report on the synthesis and labeling applications of novel red-shifted fluorogenic cell-permeable green fluorescent protein (GFP) chromophore analogs.<\/jats:p>","DOI":"10.3390\/ijms19123778","type":"journal-article","created":{"date-parts":[[2018,11,28]],"date-time":"2018-11-28T11:43:44Z","timestamp":1543405424000},"page":"3778","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Red-Shifted Aminated Derivatives of GFP Chromophore for Live-Cell Protein Labeling with Lipocalins"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2164-5698","authenticated-orcid":false,"given":"Nina G.","family":"Bozhanova","sequence":"first","affiliation":[{"name":"Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16\/10, 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9339-7603","authenticated-orcid":false,"given":"Mikhail S.","family":"Baranov","sequence":"additional","affiliation":[{"name":"Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16\/10, 117997 Moscow, Russia"},{"name":"Pirogov Russian National Research Medical University, Ostrovitianov 1, 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadezhda S.","family":"Baleeva","sequence":"additional","affiliation":[{"name":"Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16\/10, 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey S.","family":"Gavrikov","sequence":"additional","affiliation":[{"name":"Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16\/10, 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4935-7030","authenticated-orcid":false,"given":"Alexander S.","family":"Mishin","sequence":"additional","affiliation":[{"name":"Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16\/10, 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,11,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1126\/science.1207339","article-title":"RNA mimics of green fluorescent protein","volume":"333","author":"Paige","year":"2011","journal-title":"Science"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nbt1368","article-title":"Fluorogen-activating single-chain antibodies for imaging cell surface proteins","volume":"26","author":"Schmidt","year":"2008","journal-title":"Nat. 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