{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:29:24Z","timestamp":1791664164743,"version":"4.3.4"},"reference-count":85,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T00:00:00Z","timestamp":1574294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012550","name":"Nemzeti Kutat\u00e1si, Fejleszt\u00e9si \u00e9s Innovaci\u00f3s Alap","doi-asserted-by":"publisher","award":["OTKA PD112855"],"award-info":[{"award-number":["OTKA PD112855"]}],"id":[{"id":"10.13039\/501100012550","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012550","name":"Nemzeti Kutat\u00e1si, Fejleszt\u00e9si \u00e9s Innovaci\u00f3s Alap","doi-asserted-by":"publisher","award":["NKFIH FK 124871"],"award-info":[{"award-number":["NKFIH FK 124871"]}],"id":[{"id":"10.13039\/501100012550","id-type":"DOI","asserted-by":"publisher"}]},{"name":"New National Excellence Program of the Ministry of Human Capacities","award":["UNKP-18-3-I-SZTE-17 and UNKP-19-4-SZTE-86"],"award-info":[{"award-number":["UNKP-18-3-I-SZTE-17 and UNKP-19-4-SZTE-86"]}]},{"name":"J\u00e1nos Bolyai Research Scholarship of the Hungarian Academy of Sciences","award":["BO\/00743\/19\/8"],"award-info":[{"award-number":["BO\/00743\/19\/8"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Different abiotic and biotic stresses lead to the accumulation of unfolded and misfolded proteins in the endoplasmic reticulum (ER), resulting in ER stress. In response to ER stress, cells activate various cytoprotective responses, enhancing chaperon synthesis, protein folding capacity, and degradation of misfolded proteins. These responses of plants are called the unfolded protein response (UPR). ER stress signaling and UPR can be regulated by salicylic acid (SA), but the mode of its action is not known in full detail. In this review, the current knowledge on the multifaceted role of SA in ER stress and UPR is summarized in model plants and crops to gain a better understanding of SA-regulated processes at the physiological, biochemical, and molecular levels.<\/jats:p>","DOI":"10.3390\/ijms20235842","type":"journal-article","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T02:49:27Z","timestamp":1574390967000},"page":"5842","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["The Multifaceted Roles of Plant Hormone Salicylic Acid in Endoplasmic Reticulum Stress and Unfolded Protein Response"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4539-6358","authenticated-orcid":false,"given":"P\u00e9ter","family":"Po\u00f3r","sequence":"first","affiliation":[{"name":"Department of Plant Biology, University of Szeged, K\u00f6z\u00e9p fasor 52, H-6726 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zal\u00e1n","family":"Cz\u00e9kus","sequence":"additional","affiliation":[{"name":"Department of Plant Biology, University of Szeged, K\u00f6z\u00e9p fasor 52, H-6726 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma","family":"Tari","sequence":"additional","affiliation":[{"name":"Department of Plant Biology, University of Szeged, K\u00f6z\u00e9p fasor 52, H-6726 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"\u00d6rd\u00f6g","sequence":"additional","affiliation":[{"name":"Department of Plant Biology, University of Szeged, K\u00f6z\u00e9p fasor 52, H-6726 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,11,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1105\/tpc.007609","article-title":"Genomic analysis of the unfolded protein response in Arabidopsis shows its connection to important cellular processes","volume":"15","author":"Chrispeels","year":"2003","journal-title":"Plant Cell"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1172\/JCI26373","article-title":"Endoplasmic reticulum stress: Cell life and death decisions","volume":"115","author":"Xu","year":"2005","journal-title":"J. Clin. Invest."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1111\/j.1600-0854.2008.00780.x","article-title":"Endoplasmic reticulum quality control and the unfolded protein response: Insights from plants","volume":"9","author":"Vitale","year":"2008","journal-title":"Traffic"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.1038\/emboj.2009.263","article-title":"Receptor quality control in the endoplasmic reticulum for plant innate immunity","volume":"28","author":"Saijo","year":"2009","journal-title":"EMBO J."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s10709-010-9544-y","article-title":"The evolutionary history of calreticulin and calnexin genes in green plants","volume":"139","year":"2011","journal-title":"Genetica"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"232","DOI":"10.4161\/psb.6.2.15490","article-title":"Chaperones and foldases in endoplasmic reticulum stress signaling in plants","volume":"6","author":"Gupta","year":"2011","journal-title":"Plant Signaling Behav."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.1105\/tpc.110.078154","article-title":"Endoplasmic reticulum protein quality control and its relationship to environmental stress responses in plants","volume":"22","author":"Liu","year":"2010","journal-title":"Plant Cell"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"26582","DOI":"10.3390\/ijms161125964","article-title":"Endoplasmic reticulum stress signaling in plant immunity\u2014at the crossroad of life and death","volume":"16","author":"Du","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"ref_9","first-page":"74","article-title":"How does the stressed out ER find relief during virus infection?","volume":"17","author":"Verchot","year":"2016","journal-title":"Curr. Opin. Plant. Biol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"214","DOI":"10.3389\/fpls.2018.00214","article-title":"Activation of the transducers of unfolded protein response in plants","volume":"9","author":"Nawkar","year":"2018","journal-title":"Front. Plant Sci."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3389\/fpls.2014.00162","article-title":"Endoplasmic reticulum-mediated protein quality control in Arabidopsis","volume":"5","author":"Liu","year":"2014","journal-title":"Front. Plant Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s13765-016-0167-6","article-title":"Comparison and contrast of plant, yeast, and mammalian ER stress and UPR","volume":"59","author":"Chakraborty","year":"2016","journal-title":"Appl. Biol. Chem."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1093\/jxb\/ery040","article-title":"Interplay between the unfolded protein response and reactive oxygen species: A dynamic duo","volume":"69","author":"Ozgur","year":"2018","journal-title":"J. Exp. Bot."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3389\/fpls.2012.00200","article-title":"The endoplasmic reticulum in plant immunity and cell death","volume":"3","author":"Eichmann","year":"2012","journal-title":"Front. Plant Sci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e24297","DOI":"10.4161\/psb.24297","article-title":"Links between ER stress and autophagy in plants","volume":"8","author":"Pu","year":"2013","journal-title":"Plant Signal. Behav."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3389\/fpls.2014.00041","article-title":"Endoplasmic reticulum stress-induced PCD and caspase-like activities involved","volume":"5","author":"Cai","year":"2014","journal-title":"Front. Plant Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00709-015-0842-1","article-title":"Endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in plants","volume":"253","author":"Wan","year":"2016","journal-title":"Protoplasma"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1146\/annurev-arplant-050312-120053","article-title":"Endoplasmic reticulum stress responses in plants","volume":"64","author":"Howell","year":"2013","journal-title":"Annu. Rev. Plant Biol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.3389\/fpls.2019.01032","article-title":"Arabidopsis GAAP1 to GAAP3 Play Redundant Role in Cell Death Inhibition by Suppressing the Upregulation of Salicylic Acid Pathway Under Endoplasmic Reticulum Stress","volume":"10","author":"Wang","year":"2019","journal-title":"Front. Plant Sci."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.tplants.2012.06.014","article-title":"Plant transducers of the endoplasmic reticulum unfolded protein response","volume":"17","author":"Iwata","year":"2012","journal-title":"Trends Plant Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/nph.13915","article-title":"Managing the protein folding demands in the endoplasmic reticulum of plants","volume":"211","author":"Liu","year":"2016","journal-title":"New Phytol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1104\/pp.010636","article-title":"Molecular characterization of two Arabidopsis Ire1 homologs, endoplasmic reticulum-located transmembrane protein kinases","volume":"127","author":"Koizumi","year":"2001","journal-title":"Plant Physiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"5713","DOI":"10.1073\/pnas.1219047110","article-title":"Defects in IRE1 enhance cell death and fail to degrade mRNAs encoding secretory pathway proteins in the Arabidopsis unfolded protein response","volume":"110","author":"Mishiba","year":"2013","journal-title":"PNAS"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"e1005164","DOI":"10.1371\/journal.pgen.1005164","article-title":"The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast","volume":"11","author":"Zhang","year":"2015","journal-title":"PLoS Genetics"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"27362","DOI":"10.1038\/srep27362","article-title":"Divergence and conservation of the major UPR branch IRE1-bZIP signaling pathway across eukaryotes","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.1105\/tpc.106.050021","article-title":"An endoplasmic reticulum stress response in Arabidopsis is mediated by proteolytic processing and nuclear relocation of a membrane-associated transcription factor, bZIP28","volume":"19","author":"Liu","year":"2007","journal-title":"Plant Cell"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1365-313X.2012.04943.x","article-title":"Elements proximal to and within the transmembrane domain mediate the organelle-to-organelle movement of bZIP28 under ER stress conditions","volume":"70","author":"Srivastava","year":"2012","journal-title":"Plant J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1105\/tpc.113.110684","article-title":"BINDING PROTEIN is a master regulator of the endoplasmic reticulum stress sensor\/transducer bZIP28 in Arabidopsis","volume":"25","author":"Srivastava","year":"2013","journal-title":"Plant Cell"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fpls.2014.00059","article-title":"Stress sensing in plants by an ER stress sensor\/transducer, bZIP28","volume":"5","author":"Srivastava","year":"2014","journal-title":"Front. Plant Sci."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/tpj.13572","article-title":"Activation of the Arabidopsis membrane-bound transcription factor bZIP 28 is mediated by site-2 protease, but not site-1 protease","volume":"91","author":"Iwata","year":"2017","journal-title":"Plant J."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/nph.14388","article-title":"Arabidopsis B-cell lymphoma2 (Bcl-2)-associated athanogene 7 (BAG7)-mediated heat tolerance requires translocation, sumoylation and binding to WRKY29","volume":"214","author":"Li","year":"2017","journal-title":"New Phytol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/tpj.12604","article-title":"A plasma membrane-tethered transcription factor, NAC 062\/ANAC 062\/NTL 6, mediates the unfolded protein response in Arabidopsis","volume":"79","author":"Yang","year":"2014","journal-title":"Plant J."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"e1004243","DOI":"10.1371\/journal.pgen.1004243","article-title":"The membrane-associated transcription factor NAC089 controls ER-stress-induced programmed cell death in plants","volume":"10","author":"Yang","year":"2014","journal-title":"PLoS Genetics"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.tplants.2012.02.004","article-title":"NAC proteins: Regulation and role in stress tolerance","volume":"17","author":"Puranik","year":"2012","journal-title":"Trends Plant Sci."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/tpj.12287","article-title":"The plant-specific transcription factor gene NAC 103 is induced by b ZIP 60 through a new cis-regulatory element to modulate the unfolded protein response in Arabidopsis","volume":"76","author":"Sun","year":"2013","journal-title":"Plant J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.pbi.2007.08.008","article-title":"Salicylic acid in plant defence\u2014the players and protagonists","volume":"10","author":"Loake","year":"2007","journal-title":"Curr. Opin. Plant. Biol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.envexpbot.2009.08.005","article-title":"Effect of exogenous salicylic acid under changing environment: A review","volume":"68","author":"Hayat","year":"2010","journal-title":"Environ. Exp. Bot."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1146\/annurev.phyto.050908.135202","article-title":"Salicylic acid, a multifaceted hormone to combat disease","volume":"47","author":"Vlot","year":"2009","journal-title":"Annu. Rev. Phytopathol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1105\/tpc.11.10.1935","article-title":"Anticipating endoplasmic reticulum stress: A novel early response before pathogenesis-related gene induction","volume":"11","author":"Vidal","year":"1999","journal-title":"Plant Cell"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1126\/science.1108791","article-title":"Induction of protein secretory pathway is required for systemic acquired resistance","volume":"308","author":"Wang","year":"2005","journal-title":"Science"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"399","DOI":"10.3389\/fpls.2019.00399","article-title":"Endoplasmic reticulum plays a critical role in integrating signals generated by both biotic and abiotic stress in plants","volume":"10","author":"Park","year":"2019","journal-title":"Front. Plant Sci."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1093\/jxb\/err031","article-title":"Salicylic acid beyond defence: Its role in plant growth and development","volume":"62","author":"Plasencia","year":"2011","journal-title":"J. Exp. Bot."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1146\/annurev-cellbio-092910-154055","article-title":"Hormonal modulation of plant immunity","volume":"28","author":"Pieterse","year":"2012","journal-title":"Annu. Rev. Cell Dev. Bi."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/mpp.12035","article-title":"Salicylic acid: An old hormone up to new tricks","volume":"14","author":"Boatwright","year":"2013","journal-title":"Mol. Plant Pathol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S0092-8674(03)00429-X","article-title":"Inducers of plant systemic acquired resistance regulate NPR1 function through redox changes","volume":"113","author":"Mou","year":"2003","journal-title":"Cell"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.cub.2011.12.015","article-title":"The HSF-like transcription factor TBF1 is a major molecular switch for plant growth-to-defense transition","volume":"22","author":"Wang","year":"2012","journal-title":"Current Biology"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1094\/MPMI-09-11-0256","article-title":"Arabidopsis clade I TGA transcription factors regulate plant defenses in an NPR1-independent fashion","volume":"25","author":"Shearer","year":"2012","journal-title":"Mol. Plant Microbe Interact."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e77378","DOI":"10.1371\/journal.pone.0077378","article-title":"Arabidopsis clade I TGA factors regulate apoplastic defences against the bacterial pathogen Pseudomonas syringae through endoplasmic reticulum-based processes","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS ONE"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1093\/pcp\/pcu108","article-title":"Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis","volume":"55","author":"Nagashima","year":"2014","journal-title":"Plant Cell Physiol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1104\/pp.111.187773","article-title":"The extent to which methyl salicylate is required for signaling systemic acquired resistance is dependent on exposure to light after infection","volume":"157","author":"Liu","year":"2011","journal-title":"Plant Physiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.freeradbiomed.2017.12.024","article-title":"Redox and the circadian clock in plant immunity: A balancing act","volume":"119","author":"Karapetyan","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e0122936","DOI":"10.1371\/journal.pone.0122936","article-title":"The dynamic of the splicing of bZIP60 and the proteins encoded by the spliced and unspliced mRNAs reveals some unique features during the activation of UPR in Arabidopsis thaliana","volume":"10","author":"Moreno","year":"2015","journal-title":"PLoS ONE"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"E5203","DOI":"10.1073\/pnas.1802254115","article-title":"Salicylic acid-independent role of NPR1 is required for protection from proteotoxic stress in the plant endoplasmic reticulum","volume":"115","author":"Lai","year":"2018","journal-title":"PNAS"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1093\/aob\/mcv072","article-title":"The effects of induced production of reactive oxygen species in organelles on endoplasmic reticulum stress and on the unfolded protein response in Arabidopsis","volume":"116","author":"Ozgur","year":"2015","journal-title":"Ann. Bot."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1111\/tpj.14091","article-title":"NADPH oxidase activity is required for ER stress survival in plants","volume":"96","author":"Angelos","year":"2018","journal-title":"Plant J."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jplph.2017.03.013","article-title":"Prolonged dark period modulates the oxidative burst and enzymatic antioxidant systems in the leaves of salicylic acid-treated tomato","volume":"213","author":"Bela","year":"2017","journal-title":"J. Plant Physiol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s10265-019-01085-y","article-title":"Salicylic acid-induced ROS production by mitochondrial electron transport chain depends on the activity of mitochondrial hexokinases in tomato (Solanum lycopersicum L.)","volume":"132","author":"Patyi","year":"2019","journal-title":"J. Plant Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"367","DOI":"10.32615\/ps.2019.040","article-title":"Effects of salicylic acid on photosynthetic activity and chloroplast morphology under light and prolonged darkness","volume":"57","year":"2019","journal-title":"Photosynthetica"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1111\/tpj.13397","article-title":"CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses","volume":"89","author":"Meng","year":"2017","journal-title":"Plant J."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Moreno, A.A., Mukhtar, M.S., Blanco, F., Boatwright, J.L., Moreno, I., Jordan, M.R., and Pajerowska-Mukhtar, K.M. (2012). IRE1\/bZIP60-mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0031944"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/mp\/ssr115","article-title":"Conservation of IRE1-regulated bZIP74 mRNA unconventional splicing in rice (Oryza sativa L.) involved in ER stress responses","volume":"5","author":"Lu","year":"2012","journal-title":"Mol. Plant"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/srep00670","article-title":"Functional integration between defence and IRE1-mediated ER stress response in rice","volume":"2","author":"Hayashi","year":"2012","journal-title":"Sci. Rep."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/j.1365-313X.2004.02267.x","article-title":"Endogenous salicylic acid protects rice plants from oxidative damage caused by aging as well as biotic and abiotic stress","volume":"40","author":"Yang","year":"2004","journal-title":"Plant J."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1105\/tpc.106.046250","article-title":"Rice WRKY45 plays a crucial role in benzothiadiazole-inducible blast resistance","volume":"19","author":"Shimono","year":"2007","journal-title":"Plant Cell"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1111\/j.1365-313X.2011.04844.x","article-title":"Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice","volume":"69","author":"Hayashi","year":"2012","journal-title":"Plant J."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jplph.2015.03.008","article-title":"Visualization of endoplasmic reticulum stressed cells for forward genetic studies in plants","volume":"180","author":"Hayashi","year":"2015","journal-title":"J. Plant Physiol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1365-313X.2009.04091.x","article-title":"Cold activation of a plasma membrane-tethered NAC transcription factor induces a pathogen resistance response in Arabidopsis","volume":"61","author":"Seo","year":"2010","journal-title":"Plant J."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"323","DOI":"10.5423\/PPJ.RW.08.2015.0150","article-title":"Heat shock proteins: A review of the molecular chaperones for plant immunity","volume":"31","author":"Park","year":"2015","journal-title":"Plant Pathol. J."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1104\/pp.113.231928","article-title":"The endoplasmic reticulum binding protein BiP displays dual function in modulating cell death events","volume":"164","author":"Carvalho","year":"2014","journal-title":"Plant Physiol."},{"key":"ref_70","first-page":"391","article-title":"The tobacco homolog of mammalian calreticulin is present in protein complexes in vivo","volume":"7","author":"Denecke","year":"1995","journal-title":"Plant Cell"},{"key":"ref_71","first-page":"611","article-title":"Making sense of hormone-mediated defense networking: From rice to Arabidopsis","volume":"5","author":"Xu","year":"2014","journal-title":"Front. Plant Sci."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00709-012-0408-4","article-title":"Ethylene signaling in salt stress-and salicylic acid-induced programmed cell death in tomato suspension cells","volume":"250","author":"Tari","year":"2013","journal-title":"Protoplasma"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"781","DOI":"10.3389\/fpls.2015.00781","article-title":"Chloroplast signaling within, between and beyond cells","volume":"6","author":"Bobik","year":"2015","journal-title":"Front. Plant Sci."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1006\/pmpp.2000.0271","article-title":"Inhibitors of N-linked glycosylation induce systemic acquired resistance in cucumber","volume":"56","author":"Sticher","year":"2000","journal-title":"Physiol. Mol. Plant P."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Yu, X., Wang, T., Zhu, M., Zhang, L., Zhang, F., Jing, E., and Lin, T. (2019). Transcriptome and physiological analyses for revealing genes involved in wheat response to endoplasmic reticulum stress. BMC Plant Biol., 19.","DOI":"10.1186\/s12870-019-1798-7"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1105\/tpc.111.093260","article-title":"The mutualistic fungus Piriformospora indica colonizes Arabidopsis roots by inducing an endoplasmic reticulum stress\u2013triggered caspase-dependent cell death","volume":"24","author":"Qiang","year":"2012","journal-title":"Plant Cell"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1556\/018.67.2016.2.3","article-title":"Salicylic acid induced cysteine protease activity during programmed cell death in tomato plants","volume":"67","author":"Szepesi","year":"2016","journal-title":"Acta Biol. Hung."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.1074\/jbc.M706659200","article-title":"BAX inhibitor-1 modulates endoplasmic reticulum stress-mediated programmed cell death in Arabidopsis","volume":"283","author":"Watanabe","year":"2008","journal-title":"J. Biol. Chem."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.3390\/ijms10073149","article-title":"Bax inhibitor-1, a conserved cell death suppressor, is a key molecular switch downstream from a variety of biotic and abiotic stress signals in plants","volume":"10","author":"Watanabe","year":"2009","journal-title":"Int. J. Mol. Sci."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1104\/pp.107.100842","article-title":"Phosphatidylinositol 4-kinase activation is an early response to salicylic acid in Arabidopsis suspension cells","volume":"144","author":"Krinke","year":"2007","journal-title":"Plant Physiol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"687","DOI":"10.3389\/fpls.2015.00687","article-title":"The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis","volume":"6","author":"Sagor","year":"2015","journal-title":"Front. Plant Sci."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.plaphy.2016.07.020","article-title":"Comparison of polyamine metabolism in tomato plants exposed to different concentrations of salicylic acid under light or dark conditions","volume":"108","author":"Tari","year":"2016","journal-title":"Plant Physiol. Biochem."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"15973","DOI":"10.1073\/pnas.0905532106","article-title":"Specific ER quality control components required for biogenesis of the plant innate immune receptor EFR","volume":"106","author":"Li","year":"2009","journal-title":"PNAS"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/j.1365-313X.2011.04807.x","article-title":"A dual regulatory role of Arabidopsis calreticulin-2 in plant innate immunity","volume":"69","author":"Qiu","year":"2012","journal-title":"Plant J."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1094\/MPMI-12-12-0301-R","article-title":"Nicotiana benthamiana calreticulin 3a is required for the ethylene-mediated production of phytoalexins and disease resistance against oomycete pathogen Phytophthora infestans","volume":"26","author":"Matsukawa","year":"2013","journal-title":"Mol. Plant Microbe Interact."}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/20\/23\/5842\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:36:20Z","timestamp":1760189780000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/20\/23\/5842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,21]]},"references-count":85,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2019,12]]}},"alternative-id":["ijms20235842"],"URL":"https:\/\/doi.org\/10.3390\/ijms20235842","relation":{},"ISSN":["1422-0067"],"issn-type":[{"value":"1422-0067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,21]]}}}