{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:29:31Z","timestamp":1791664171526,"version":"4.3.4"},"reference-count":53,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T00:00:00Z","timestamp":1576540800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["17-05151S"],"award-info":[{"award-number":["17-05151S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003335","name":"MEYS","doi-asserted-by":"publisher","award":["LM2018100"],"award-info":[{"award-number":["LM2018100"]}],"id":[{"id":"10.13039\/501100003335","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Czech Academy of Sciences,","award":["PPPLZ, TK 919220"],"award-info":[{"award-number":["PPPLZ, TK 919220"]}]},{"DOI":"10.13039\/100012825","name":"International Visegrad Fund","doi-asserted-by":"publisher","award":["51810647"],"award-info":[{"award-number":["51810647"]}],"id":[{"id":"10.13039\/100012825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Charles University in Prague","doi-asserted-by":"publisher","award":["Student grant, GAUK_992416"],"award-info":[{"award-number":["Student grant, GAUK_992416"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["CZ.02.1.01\/0.0\/0.0\/16_019\/0000738"],"award-info":[{"award-number":["CZ.02.1.01\/0.0\/0.0\/16_019\/0000738"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The phytohormone salicylic acid (SA) has a crucial role in plant physiology. Its role is best described in the context of plant response to pathogen attack. During infection, SA is rapidly accumulated throughout the green tissues and is important for both local and systemic defences. However, some genetic\/metabolic variations can also result in SA overaccumulation in plants, even in basal conditions. To date, more than forty Arabidopsis thaliana mutants have been described as having enhanced endogenous SA levels or constitutively activated SA signalling pathways. In this study, we established a collection of mutants containing different SA levels due to diverse genetic modifications and distinct gene functions. We chose prototypic SA-overaccumulators (SA-OAs), such as bon1-1, but also \u201cnon-typical\u201d ones such as exo70b1-1; the selection of OA is accompanied by their crosses with SA-deficient lines. Here, we extensively studied the plant development and SA level\/signalling under various growth conditions in soil and in vitro, and showed a strong negative correlation between rosette size, SA content and PR1\/ICS1 transcript signature. SA-OAs (namely cpr5, acd6, bon1-1, fah1\/fah2 and pi4k\u03b21\u03b22) had bigger rosettes under high light conditions, whereas WT plants did not. Our data provide new insights clarifying a link between SA and plant behaviour under environmental stresses. The presented SA mutant collection is thus a suitable tool to shed light on the mechanisms underlying trade-offs between growth and defence in plants.<\/jats:p>","DOI":"10.3390\/ijms20246365","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T03:19:36Z","timestamp":1576811976000},"page":"6365","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["\u201cSalicylic Acid Mutant Collection\u201d as a Tool to Explore the Role of Salicylic Acid in Regulation of Plant Growth under a Changing Environment"],"prefix":"10.3390","volume":"20","author":[{"given":"Kamila","family":"Pluha\u0159ov\u00e1","sequence":"first","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"},{"name":"Department of Biochemistry and Microbiology, University of Chemistry and Technology, 16628 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Leontovy\u010dov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"},{"name":"Department of Biochemistry and Microbiology, University of Chemistry and Technology, 16628 Prague, Czech Republic"},{"name":"Department of Biochemistry, Faculty of Science, Charles University in Prague, 11000 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u011bra","family":"Stoudkov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"},{"name":"Department of Biochemistry and Microbiology, University of Chemistry and Technology, 16628 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romana","family":"Posp\u00edchalov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Mar\u0161\u00edk","sequence":"additional","affiliation":[{"name":"Department of Food Science, The Faculty of Agrobiology, Food and Natural Resources, The Czech University of Life Sciences Prague, 16500 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Klou\u010dek","sequence":"additional","affiliation":[{"name":"Department of Food Science, The Faculty of Agrobiology, Food and Natural Resources, The Czech University of Life Sciences Prague, 16500 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasiia","family":"Starodubtseva","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"},{"name":"Department of Biochemistry and Microbiology, University of Chemistry and Technology, 16628 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oksana","family":"Iakovenko","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"},{"name":"Department of Biochemistry and Microbiology, University of Chemistry and Technology, 16628 Prague, Czech Republic"},{"name":"V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 02094 Kyiv, Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuzana","family":"Kr\u010dkov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1145-0045","authenticated-orcid":false,"given":"Olga","family":"Valentov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology, University of Chemistry and Technology, 16628 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Burketov\u00e1","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4521-0533","authenticated-orcid":false,"given":"Martin","family":"Janda","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"},{"name":"Department of Biochemistry and Microbiology, University of Chemistry and Technology, 16628 Prague, Czech Republic"},{"name":"Genetics, Faculty of Biology, Ludwig-Maximilians-University of Munich (LMU), D-82152 Martinsried, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2843-5482","authenticated-orcid":false,"given":"Tetiana","family":"Kalachova","sequence":"additional","affiliation":[{"name":"Institute of Experimental Botany of the Czech Academy of Sciences, 16502 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,12,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1104\/pp.106.082057","article-title":"Proteomic Investigation of the Effect of Salicylic Acid on Arabidopsis Seed Germination and Establishment of Early Defense Mechanisms","volume":"141","author":"Rajjou","year":"2006","journal-title":"Plant Physiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1046\/j.1365-313X.2001.01158.x","article-title":"A role for salicylic acid and NPR1 in regulating cell growth in Arabidopsis","volume":"28","author":"Vanacker","year":"2001","journal-title":"Plant J. Cell Mol. Biol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1046\/j.1365-313X.2003.01954.x","article-title":"Salicylic acid regulates flowering time and links defence responses and reproductive development","volume":"37","author":"Pons","year":"2004","journal-title":"Plant J. Cell Mol. Biol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1093\/jxb\/ert085","article-title":"Salicylic acid improves salinity tolerance in Arabidopsis by restoring membrane potential and preventing salt-induced K+ loss via a GORK channel","volume":"64","author":"Jayakannan","year":"2013","journal-title":"J. Exp. Bot."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e1581560","DOI":"10.1080\/15592324.2019.1581560","article-title":"Ultraviolet radiation enhances salicylic acid-mediated defense signaling and resistance to Pseudomonas syringae DC3000 in a jasmonic acid-deficient tomato mutant","volume":"14","author":"Bravo","year":"2019","journal-title":"Plant Signal. Behav."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1094\/MPMI-03-18-0067-CR","article-title":"Systemic Acquired Resistance and Salicylic Acid: Past, Present, and Future","volume":"31","author":"Klessig","year":"2018","journal-title":"Mol. Plant Microbe Interact. MPMI"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.pbi.2019.02.004","article-title":"Salicylic acid: Biosynthesis, perception, and contributions to plant immunity","volume":"50","author":"Zhang","year":"2019","journal-title":"Curr. Opin. Plant Biol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/35107108","article-title":"Isochorismate synthase is required to synthesize salicylic acid for plant defence","volume":"414","author":"Wildermuth","year":"2001","journal-title":"Nature"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1126\/science.266.5188.1247","article-title":"A central role of salicylic Acid in plant disease resistance","volume":"266","author":"Delaney","year":"1994","journal-title":"Science"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1016\/j.febslet.2011.04.039","article-title":"Salicylic acid and its location in response to biotic and abiotic stress","volume":"585","author":"Serrano","year":"2011","journal-title":"FEBS Lett."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1146\/annurev.phyto.43.040204.135923","article-title":"Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens","volume":"43","author":"Glazebrook","year":"2005","journal-title":"Annu. Rev. Phytopathol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1111\/j.1365-3040.2010.02194.x","article-title":"Structure-function analysis of npr1 alleles in Arabidopsis reveals a role for its paralogs in the perception of salicylic acid","volume":"33","author":"Canet","year":"2010","journal-title":"Plant Cell Environ."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3389\/fpls.2014.00763","article-title":"A large-scale genetic screen for mutants with altered salicylic acid accumulation in Arabidopsis","volume":"5","author":"Ding","year":"2015","journal-title":"Front. Plant Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1093\/jxb\/err031","article-title":"Salicylic acid beyond defence: Its role in plant growth and development","volume":"62","author":"Plasencia","year":"2011","journal-title":"J. Exp. Bot."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1094\/MPMI-20-11-1449","article-title":"The TIR-NB-LRR Gene SNC1 Is Regulated at the Transcript Level by Multiple Factors","volume":"20","author":"Li","year":"2007","journal-title":"Mol. Plant. Microbe Interact."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e100303","DOI":"10.15252\/embj.2018100303","article-title":"A dual role for cell plate-associated PI4K\u03b2 in endocytosis and phragmoplast dynamics during plant somatic cytokinesis","volume":"38","author":"Lin","year":"2019","journal-title":"EMBO J."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Kalachova, T., Janda, M., \u0160a\u0161ek, V., Ortmannov\u00e1, J., Nov\u00e1kov\u00e1, P., Dobrev, I.P., Kravets, V., Guivarc\u2019h, A., Moura, D., and Burketov\u00e1, L. (2019). Identification of salicylic acid-independent responses in an Arabidopsis phosphatidylinositol 4-kinase beta double mutant. Ann. Bot.","DOI":"10.1093\/aob\/mcz112"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1111\/tra.12101","article-title":"Arabidopsis Exocyst Subcomplex Containing Subunit EXO70B1 Is Involved in Autophagy-Related Transport to the Vacuole","volume":"14","author":"Kulich","year":"2013","journal-title":"Traffic"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1111\/j.1469-8137.2012.04351.x","article-title":"Arabidopsis mutants of sphingolipid fatty acid \u03b1-hydroxylases accumulate ceramides and salicylates","volume":"196","author":"Feussner","year":"2012","journal-title":"New Phytol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1046\/j.0960-7412.2001.01228.x","article-title":"Identification of a novel gene HYS1\/CPR5 that has a repressive role in the induction of leaf senescence and pathogen-defence responses in Arabidopsis thaliana","volume":"29","author":"Yoshida","year":"2002","journal-title":"Plant J."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1105\/tpc.11.9.1695","article-title":"The Gain-of-Function Arabidopsis acd6 Mutant Reveals Novel Regulation and Function of the Salicylic Acid Signaling Pathway in Controlling Cell Death, Defenses, and Cell Growth","volume":"11","author":"Rate","year":"1999","journal-title":"Plant Cell"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1083\/jcb.200508116","article-title":"A role for the RabA4b effector protein PI-4Kbeta1 in polarized expansion of root hair cells in Arabidopsis thaliana","volume":"172","author":"Preuss","year":"2006","journal-title":"J. Cell Biol."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Vorwerk, S., Schiff, C., Santamaria, M., Koh, S., Nishimura, M., Vogel, J., Somerville, C., and Somerville, S. (2007). EDR2 negatively regulates salicylic acid-based defenses and cell death during powdery mildew infections of Arabidopsis thaliana. BMC Plant Biol., 7.","DOI":"10.1186\/1471-2229-7-35"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1126\/science.1086716","article-title":"Loss of a callose synthase results in salicylic acid-dependent disease resistance","volume":"301","author":"Nishimura","year":"2003","journal-title":"Science"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1111\/nph.12822","article-title":"Constitutive salicylic acid accumulation in pi4kIII\u03b21\u03b22 Arabidopsis plants stunts rosette but not root growth","volume":"203","author":"Janda","year":"2014","journal-title":"New Phytol."},{"key":"ref_26","first-page":"1393","article-title":"Salicylic Acid Induction\u2014Deficient Mutants of Arabidopsis Express PR-2 and PR-5 and Accumulate High Levels of Camalexin after Pathogen Inoculation","volume":"11","author":"Nawrath","year":"1999","journal-title":"Plant Cell"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1093\/jexbot\/51.345.659","article-title":"Chlorophyll fluorescence\u2014A practical guide","volume":"51","author":"Maxwell","year":"2000","journal-title":"J. Exp. Bot."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1023\/B:PRES.0000040446.87305.f4","article-title":"A Simple Alternative Approach to Assessing the Fate of Absorbed Light Energy Using Chlorophyll Fluorescence","volume":"82","author":"Hendrickson","year":"2004","journal-title":"Photosynth. Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.4161\/psb.6.10.18165","article-title":"Illumination of Arabidopsis roots induces immediate burst of ROS production","volume":"6","author":"Yokawa","year":"2011","journal-title":"Plant Signal. Behav."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/tpj.12998","article-title":"D-Root: A system for cultivating plants with the roots in darkness or under different light conditions","volume":"84","author":"Manzano","year":"2015","journal-title":"Plant J."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.envexpbot.2014.07.003","article-title":"Magical mystery tour: Salicylic acid signalling","volume":"114","author":"Janda","year":"2015","journal-title":"Environ. Exp. Bot."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jgg.2011.03.001","article-title":"Suppression of edr2-mediated powdery mildew resistance, cell death and ethylene-induced senescence by mutations in ALD1 in Arabidopsis","volume":"38","author":"Nie","year":"2011","journal-title":"J. Genet. Genom. Yi Chuan Xue Bao"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Smith, L.M., Bomblies, K., and Weigel, D. (2011). Complex evolutionary events at a tandem cluster of Arabidopsis thaliana genes resulting in a single-locus genetic incompatibility. PLoS Genet., 7.","DOI":"10.1371\/journal.pgen.1002164"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Zhu, W., Zaidem, M., Van de Weyer, A.L., Gutaker, R.M., Chae, E., Kim, S.T., Bemm, F., Li, L., Todesco, M., and Schwab, R. (2018). Modulation of ACD6 dependent hyperimmunity by natural alleles of an Arabidopsis thaliana NLR resistance gene. PLOS Genet., 14.","DOI":"10.1101\/300798"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/pcp\/pcp171","article-title":"SIZ1 controls cell growth and plant development in Arabidopsis through salicylic acid","volume":"51","author":"Miura","year":"2010","journal-title":"Plant Cell Physiol."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Todesco, M., Kim, S.T., Chae, E., Bomblies, K., Zaidem, M., Smith, L.M., Weigel, D., and Laitinen, R.A.E. (2014). Activation of the Arabidopsis thaliana Immune System by Combinations of Common ACD6 Alleles. PLoS Genet., 10.","DOI":"10.1371\/journal.pgen.1004459"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1104\/pp.112.211011","article-title":"Elevated Early Callose Deposition Results in Complete Penetration Resistance to Powdery Mildew in Arabidopsis","volume":"161","author":"Ellinger","year":"2013","journal-title":"Plant Physiol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1104\/pp.100.3.1541","article-title":"Role of Salicylic Acid and Benzoic Acid in Flowering of a Photoperiod-Insensitive Strain, Lemna paucicostata LP6 1","volume":"100","author":"Khurana","year":"1992","journal-title":"Plant Physiol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"e1345404","DOI":"10.1080\/15592324.2017.1345404","article-title":"Impact of salicylic acid- and jasmonic acid-regulated defences on root colonization by Trichoderma harzianum T-78","volume":"12","author":"Appels","year":"2017","journal-title":"Plant Signal. Behav."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1469-8137.2008.02458.x","article-title":"Transcriptome analysis of Arabidopsis roots treated with signaling compounds: A focus on signal transduction, metabolic regulation and secretion","volume":"179","author":"Badri","year":"2008","journal-title":"New Phytol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1104\/pp.19.00130","article-title":"Salicylic Acid Affects Root Meristem Patterning via Auxin Distribution in a Concentration-Dependent Manner","volume":"180","author":"Pasternak","year":"2019","journal-title":"Plant Physiol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1093\/jxb\/ert133","article-title":"A wheat PI4K gene whose product possesses threonine autophophorylation activity confers tolerance to drought and salt in Arabidopsis","volume":"64","author":"Liu","year":"2013","journal-title":"J. Exp. Bot."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Borghi, M., Rus, A., and Salt, D.E. (2011). Loss-of-Function of Constitutive Expresser of Pathogenesis Related Genes5 Affects Potassium Homeostasis in Arabidopsis thaliana. PLoS ONE, 6.","DOI":"10.1371\/journal.pone.0026360"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Gao, G., Zhang, S., Wang, C., Yang, X., Wang, Y., Su, X., Du, J., and Yang, C. (2011). Arabidopsis CPR5 independently regulates seed germination and postgermination arrest of development through LOX pathway and ABA signaling. PLoS ONE, 6.","DOI":"10.1371\/journal.pone.0019406"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Okuma, E., Nozawa, R., Murata, Y., and Miura, K. (2014). Accumulation of endogenous salicylic acid confers drought tolerance to Arabidopsis. Plant Signal. Behav., 9.","DOI":"10.4161\/psb.28085"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3239","DOI":"10.1093\/jxb\/erm169","article-title":"Distinct modulations of the hexokinase1-mediated glucose response and hexokinase1-independent processes by HYS1\/CPR5 in Arabidopsis","volume":"58","author":"Aki","year":"2007","journal-title":"J. Exp. Bot."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1093\/aob\/mcw284","article-title":"Plant immunity: Unravelling the complexity of plant responses to biotic stresses","volume":"119","author":"Miller","year":"2017","journal-title":"Ann. Bot."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.chom.2014.03.014","article-title":"At the intersection of plant growth and immunity","volume":"15","author":"Wang","year":"2014","journal-title":"Cell Host Microbe"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1105\/tpc.16.00931","article-title":"Mechanisms to Mitigate the Trade-Off between Growth and Defense","volume":"29","author":"Karasov","year":"2017","journal-title":"Plant Cell"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: An open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"103867","DOI":"10.1016\/j.envexpbot.2019.103867","article-title":"Interplay between phosphoinositides and actin cytoskeleton in the regulation of immunity related responses in Arabidopsis thaliana seedlings","volume":"167","author":"Kalachova","year":"2019","journal-title":"Environ. Exp. Bot."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1104\/pp.110.157370","article-title":"Functional Analysis of the Arabidopsis PAL Gene Family in Plant Growth, Development, and Response to Environmental Stress","volume":"153","author":"Huang","year":"2010","journal-title":"Plant Physiol."},{"key":"ref_53","unstructured":"Simko, W. (2018, August 02). R Package \u201cCorrplot\u201d: Visualization of a Correlation Matrix (Version 0.84). Available online: https:\/\/github.com\/taiyun\/corrplot."}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/20\/24\/6365\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:43:08Z","timestamp":1760190188000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/20\/24\/6365"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,17]]},"references-count":53,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2019,12]]}},"alternative-id":["ijms20246365"],"URL":"https:\/\/doi.org\/10.3390\/ijms20246365","relation":{},"ISSN":["1422-0067"],"issn-type":[{"value":"1422-0067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,17]]}}}