{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T17:27:54Z","timestamp":1788629274653,"version":"build-2803163510"},"reference-count":66,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T00:00:00Z","timestamp":1583452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Nature Science Foundation of China","award":["31425017"],"award-info":[{"award-number":["31425017"]}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2017YFD0300410"],"award-info":[{"award-number":["2017YFD0300410"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Modified gibberellin (GA) signaling leads to semi-dwarfism with low nitrogen (N) use efficiency (NUE) in crops. An understanding of GA-mediated N uptake is essential for the development of crops with improved NUE. The function of GA in modulating N uptake capacity and nitrate (NO3\u2212) transporters (NRTs) was analyzed in the GA synthesis-deficient mutant zmga3ox grown under low (LN) and sufficient (SN) N conditions. LN significantly suppressed the production of GA1, GA3, and GA4, and the zmga3ox plants showed more sensitivity in shoots as well as LN stress. Moreover, the higher anthocyanin accumulation and the decrease of chlorophyll content were also recorded. The net NO3\u2212 fluxes and 15N content were decreased in zmga3ox plants under both LN and SN conditions. Exogenous GA3 could restore the NO3\u2212 uptake in zmga3ox plants, but uniconazole repressed NO3\u2212 uptake. Moreover, the transcript levels of ZmNRT2.1\/2.2 were downregulated in zmga3ox plants, while the GA3 application enhanced the expression level. Furthermore, the RNA-seq analyses identified several transcription factors that are involved in the GA-mediated transcriptional operation of NRTs related genes. These findings revealed that GAs influenced N uptake involved in the transcriptional regulation of NRTs and physiological responses in maize responding to nitrogen supply.<\/jats:p>","DOI":"10.3390\/ijms21051824","type":"journal-article","created":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T09:26:41Z","timestamp":1583486801000},"page":"1824","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["The Role of Gibberellins in Regulation of Nitrogen Uptake and Physiological Traits in Maize Responding to Nitrogen Availability"],"prefix":"10.3390","volume":"21","author":[{"given":"Yubin","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Yao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1552-6796","authenticated-orcid":false,"given":"Yushi","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuexia","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiapeng","family":"Xing","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benzhou","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohua","family":"Mi","sequence":"additional","affiliation":[{"name":"College of Resources and Environmental Science, Department of Plant Nutrition, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohu","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"},{"name":"Center for Crop Functional Genomics and Molecular Breeding, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingcai","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Physiology and Biochemistry, Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,6]]},"reference":[{"key":"ref_1","first-page":"225","article-title":"Gibberellin metabolism and its regulation","volume":"59","author":"Yamaguchi","year":"2008","journal-title":"J. Plant Growth Regul."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1242\/jeb.089938","article-title":"The role of gibberellin signalling in plant responses to abiotic stress","volume":"217","author":"Colebrook","year":"2014","journal-title":"J. Exp. Biol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1104\/pp.114.247486","article-title":"The maize DWARF1 encodes a Gibberellin 3-Oxidase and is dual localized to the nucleus and cytosol","volume":"166","author":"Chen","year":"2014","journal-title":"Plant Physiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1105\/tpc.111.095109","article-title":"Analysis of the developmental roles of the Arabidopsis gibberellin 20-oxidases demonstrates that GA20ox1, -2, and-3 are the dominant paralogs","volume":"24","author":"Plackett","year":"2012","journal-title":"Plant Cell"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1105\/tpc.109.066969","article-title":"The angiosperm Gibberellin-GID1-DELLA growth regulatory mechanism: How an \u201cinhibitor of an inhibitor\u201d enables flexible response to fluctuating environments","volume":"21","author":"Harberd","year":"2009","journal-title":"Plant Cell"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/nbt0803-873","article-title":"Constructing dwarf rice","volume":"21","author":"Hedden","year":"2003","journal-title":"Nat. Biotechnol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/22307","article-title":"\u2018Green revolution\u2019 genes encode mutant gibberellin response modulators","volume":"400","author":"Peng","year":"1999","journal-title":"Nature"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1105\/tpc.010319","article-title":"The gibberellin signaling pathway is regulated by the appearance and disappearance of SLENDER RICE1 in nuclei","volume":"14","author":"Itoh","year":"2002","journal-title":"Plant Cell"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"11034","DOI":"10.1073\/pnas.1019490108","article-title":"Artificial selection for a green revolution gene during japonica rice domestication","volume":"108","author":"Asano","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1038\/s41586-018-0415-5","article-title":"Modulating plant growth-metabolism coordination for sustainable agriculture","volume":"560","author":"Li","year":"2018","journal-title":"Nature"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1104\/pp.107.103788","article-title":"Phosphate starvation root architecture and anthocyanin accumulation responses are modulated by the Gibberellin-DELLA signaling pathway in Arabidopsis","volume":"145","author":"Jiang","year":"2007","journal-title":"Plant Physiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jplph.2019.02.007","article-title":"Gibberellins play dual roles in response to phosphate starvation of tomato seedlings, negatively in shoots but positively in roots","volume":"234","author":"Zhang","year":"2019","journal-title":"J. Plant Physiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1080\/15592324.2017.1366396","article-title":"How DELLAs contribute to control potassium uptake under conditions of potassium scarcity? hypotheses and uncertainties","volume":"12","author":"Oliferuk","year":"2017","journal-title":"Plant Signal. Behav."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00299-017-2102-7","article-title":"GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation","volume":"36","author":"Zhang","year":"2017","journal-title":"Plant Cell Rep."},{"key":"ref_15","first-page":"145","article-title":"Effect of gibberellic acid on carbonic anhydrase, photosynthesis, growth and yield of mustard","volume":"38","author":"Khan","year":"1996","journal-title":"Biol. Plant."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1046\/j.1365-3040.2002.00871.x","article-title":"Changes in the acquisition and partitioning of carbon and nitrogen in the gibberellin-deficient mutants A70 and W335 of tomato (Solanum lycopersicum L.)","volume":"25","author":"Nagel","year":"2002","journal-title":"Plant Cell Environ."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Bai, L.Q., Deng, H.Q., Zhang, X.C., Yu, X.C., and Li, Y.S. (2016). Gibberellin is involved in inhibition of cucumber growth and nitrogen uptake at suboptimal root-zone temperatures. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0156188"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1017\/S0021859611000414","article-title":"Effect of wheat dwarfing genes on nitrogen-use efficiency","volume":"150","author":"Gooding","year":"2012","journal-title":"J. Agric. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev-arplant-042811-105532","article-title":"Plant nitrogen assimilation and use efficiency","volume":"63","author":"Xu","year":"2012","journal-title":"Annu. Rev. Plant Biol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"12302","DOI":"10.1073\/pnas.0912953109","article-title":"Green Revolution: Impacts, limits, and the path ahead","volume":"109","author":"Pingali","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.copbio.2014.11.015","article-title":"Regulation of plant root system architecture: Implications for crop advancement","volume":"32","author":"Rogers","year":"2015","journal-title":"Curr. Opin. Biotechnol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"105011","DOI":"10.1088\/1748-9326\/9\/10\/105011","article-title":"50 year trends in nitrogen use efficiency of world cropping systems: The relationship between yield and nitrogen input to cropland","volume":"9","author":"Lassaletta","year":"2014","journal-title":"Environ. Res. Lett."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1093\/jxb\/erm097","article-title":"The challenge of improving nitrogen use efficiency in crop plants: Towards a more central role for genetic variability and quantitative genetics within integrated approaches","volume":"58","author":"Hirel","year":"2007","journal-title":"J. Exp. Bot."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1104\/pp.117.1.283","article-title":"Drought-induced effects on nitrate reductase activity and mRNA and on the coordination of nitrogen and carbon metabolism in maize leaves","volume":"1","author":"Foyer","year":"1998","journal-title":"Plant Physiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1016\/j.febslet.2007.04.047","article-title":"Nitrate transporters and peptide transporters","volume":"581","author":"Tsay","year":"2007","journal-title":"FEBS Lett."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.tplants.2013.08.008","article-title":"A unified nomenclature of NITRATE TRANSPORTER 1\/PEPTIDE TRANSPORTER family members in plants","volume":"19","author":"Leran","year":"2014","journal-title":"Trends Plant Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1093\/jxb\/erq410","article-title":"Hormonal control of nitrogen acquisition: Roles of auxin, abscisic acid, and cytokinin","volume":"62","author":"Kiba","year":"2011","journal-title":"J. Exp. Bot."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.envexpbot.2018.03.012","article-title":"Gibberellins synthesis is involved in the reduction of cell flux and elemental growth rate in maize leaf under low nitrogen supply","volume":"150","author":"Mu","year":"2018","journal-title":"Environ. Exp. Bot."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Xing, H.L., Dong, L., Wang, Z.P., Zhang, H.Y., Han, C.Y., Liu, B., Wang, X.C., and Chen, Q.J. (2014). A CRISPR\/Cas9 toolkit for multiplex genome editing in plants. BMC Plant Biol., 14.","DOI":"10.1186\/s12870-014-0327-y"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Zhao, L.F., Liu, F., Crawford, N.M., and Yong, W. (2018). Molecular regulation of nitrate response in plants. Int. J. Mol. Sci., 19.","DOI":"10.3390\/ijms19072039"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Naing, A.H., Park, K.I., Ai, T.N., Chung, M.Y., Han, J.S., Kang, Y.W., Lim, K.B., and Kim, C.K. (2017). Overexpression of snapdragon Delila (Del) gene in tobacco enhances anthocyanin accumulation and abiotic stress tolerance. BMC Plant Biol., 17.","DOI":"10.1186\/s12870-017-1015-5"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.4014\/jmb.1307.07024","article-title":"Enhanced salt stress tolerance in transgenic potato plants expressing IbMYB1, a sweet potato transcription factor","volume":"23","author":"Cheng","year":"2013","journal-title":"J. Microbiol. Biotechnol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.pbi.2017.05.010","article-title":"Plant nitrogen nutrition: Sensing and signaling","volume":"39","author":"Xuan","year":"2017","journal-title":"Curr. Biol. Plant Biol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1105\/tpc.16.00724","article-title":"Maize NPF6 proteins are homologs of Arabidopsis CHL1 that are selective for both nitrate and chloride","volume":"29","author":"Wen","year":"2017","journal-title":"Plant Cell"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1105\/tpc.17.00809","article-title":"Expression of the nitrate transporter gene OsNRT1.1A\/OsNPF6.3 confers high yield and early maturation in rice","volume":"30","author":"Wang","year":"2018","journal-title":"Plant Cell"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.cell.2009.07.004","article-title":"CHL1 functions as a nitrate sensor in plants","volume":"138","author":"Ho","year":"2009","journal-title":"Cell"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/nph.14396","article-title":"Nitrogen Limitation Adaptation (NLA) is involved in source-to-sink remobilization of nitrate by mediating the degradation of NRT1.7 in Arabidopsis","volume":"214","author":"Liu","year":"2017","journal-title":"New Physiol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1104\/pp.106.091223","article-title":"Dissection of the AtNRT2.1:AtNRT2.2 inducible high-affinity nitrate transporter gene cluster","volume":"143","author":"Li","year":"2007","journal-title":"Plant Physiol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3389\/fpls.2018.00722","article-title":"Knock-Down of CsNRT2.1, a Cucumber Nitrate Transporter, Reduces Nitrate Uptake, Root length, and Lateral Root Number at Low External Nitrate Concentration","volume":"9","author":"Li","year":"2018","journal-title":"Front. Plant Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1111\/j.1365-3040.2011.02335.x","article-title":"Rice OsNAR2.1 interacts with OsNRT2.1, OsNRT2.2 and OsNRT2.3a nitrate transporters to provide uptake over high and low concentration ranges","volume":"34","author":"Yan","year":"2011","journal-title":"Plant Cell Environ."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/nph.12166","article-title":"The response of the maize nitrate transport system to nitrogen demand and supply across the lifecycle","volume":"198","author":"Garnett","year":"2013","journal-title":"New Phytol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s004250050372","article-title":"Regulation of GmNRT2 expression and nitrate transport activity in roots of soybean (Glycine max)","volume":"206","author":"Amarasinghe","year":"1998","journal-title":"Planta"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1104\/pp.123.1.307","article-title":"Regulation of high-affinity nitrate transporter genes and high-affinity nitrate influx by nitrogen pools in roots of barley","volume":"123","author":"Vidmar","year":"2000","journal-title":"Plant Physiol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1093\/jexbot\/53.370.825","article-title":"Nitrate transport in plants: Which gene and which control?","volume":"53","author":"Orsel","year":"2002","journal-title":"J. Exp. Bot."},{"key":"ref_45","unstructured":"Zhou, X., Liu, M.Y., Wu, W.H., and Wang, Y. (2019). Phosphorylation at Ser28 stabilizes the Arabidopsis nitrate transporter NRT2.1 in response to nitrate limitation. J. Integr. Plant Biol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1046\/j.1365-313X.1999.00396.x","article-title":"Regulation of a putative high-affinity nitrate transporter (Nrt2;1At) in roots of Arabidopsis thaliana","volume":"17","author":"Zhuo","year":"1999","journal-title":"Plant J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1105\/tpc.013516","article-title":"Regulation of root ion transporters by photosynthesis: Functional importance and relation with hexokinase","volume":"15","author":"Lejay","year":"2003","journal-title":"Plant Cell"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.devcel.2016.03.022","article-title":"Tissue-specific regulation of gibberellin signaling article tissue-specific regulation of gibberellin signaling fine-tunes Arabidopsis iron-deficiency responses","volume":"37","author":"Wild","year":"2016","journal-title":"Dev. Cell"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.cub.2014.07.012","article-title":"Report class I TCP-DELLA interactions in inflorescence shoot apex determine plant height","volume":"24","author":"Daviere","year":"2014","journal-title":"Curr. Biol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1104\/pp.71.3.618","article-title":"Nitrate reductase activity in shoots and roots of maize seedlings as affected by the form of nitrogen nutrition and the pH of the nutrient solution","volume":"71","author":"Mengel","year":"1983","journal-title":"Plant Physiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s00425-012-1807-7","article-title":"Net fluxes of ammonium and nitrate in association with H+ fluxes in fine roots of Populus popularis","volume":"237","author":"Luo","year":"2013","journal-title":"Planta"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s11104-006-9051-1","article-title":"Physiological and molecular responses of nitrogen-starved rice plants to re-supply of different nitrogen sources","volume":"287","author":"Li","year":"2006","journal-title":"Plant Soil"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/tpj.13712","article-title":"The K+ channel KZM2 is involved in stomatal movement by modulating inward K+ currents in maize guard cells","volume":"92","author":"Gao","year":"2017","journal-title":"Plant J."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"R36","DOI":"10.1186\/gb-2013-14-4-r36","article-title":"TopHat2 accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions","volume":"14","author":"Kim","year":"2013","journal-title":"Genome Biol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: A bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"W64","DOI":"10.1093\/nar\/gkq310","article-title":"agriGO: A GO analysis toolkit for the agricultural community","volume":"38","author":"Du","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"W720","DOI":"10.1093\/nar\/gkl167","article-title":"KOBAS server: A web-based platform for automated annotation and pathway identification","volume":"34","author":"Wu","year":"2006","journal-title":"Nucleic Acids Res."},{"key":"ref_59","first-page":"1544","article-title":"A general framework for weighted gene co-expression network analysis","volume":"4","author":"Zhang","year":"2005","journal-title":"Genet. Mol. Biol."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Langfelder, P., and Horvath, S. (2008). WGCNA: An R package for weighted correlation network analysis. BMC Bioinform., 9.","DOI":"10.1186\/1471-2105-9-559"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/nmeth.2212","article-title":"A travel guide to Cytoscape plugins","volume":"9","author":"Saito","year":"2012","journal-title":"Nat. Methods"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"D1040","DOI":"10.1093\/nar\/gkw982","article-title":"PlantTFDB 4.0: Toward a central hub for transcription factors and regulatory interactions in plants","volume":"45","author":"Jin","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Ma, X.D., Ma, J., Zhai, H.H., Xin, P.Y., Chu, J.F., Qiao, Y.L., and Han, L.Z. (2015). CHR729 is a CHD3 protein that controls seedling development in rice. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0138934"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/pce.13451","article-title":"The roles of jasmonate signalling in nitrogen uptake and allocation in rice (Oryza sativa L.)","volume":"42","author":"Wu","year":"2018","journal-title":"Plant Cell Environ."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-313X.2006.02973.x","article-title":"HY5 is a point of convergence between cryptochrome and cytokinin signalling pathways in Arabidopsis thaliana","volume":"49","author":"Vandenbussche","year":"2007","journal-title":"Plant J."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s10535-015-0564-4","article-title":"Effect of salicylic acid on the antioxidant system and photosystem II in wheat seedlings","volume":"60","author":"Chen","year":"2016","journal-title":"Biol. Plant."}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/21\/5\/1824\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:04:48Z","timestamp":1760173488000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/21\/5\/1824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,6]]},"references-count":66,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,3]]}},"alternative-id":["ijms21051824"],"URL":"https:\/\/doi.org\/10.3390\/ijms21051824","relation":{},"ISSN":["1422-0067"],"issn-type":[{"value":"1422-0067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,6]]}}}