{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T20:08:56Z","timestamp":1778184536888,"version":"3.51.4"},"reference-count":141,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T00:00:00Z","timestamp":1631491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.<\/jats:p>","DOI":"10.3390\/ijms22189861","type":"journal-article","created":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T21:37:12Z","timestamp":1631569032000},"page":"9861","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches"],"prefix":"10.3390","volume":"22","author":[{"given":"Boriss","family":"Strumfs","sequence":"first","affiliation":[{"name":"Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, Latvia"},{"name":"Department of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romans","family":"Uljanovs","sequence":"additional","affiliation":[{"name":"Department of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirils","family":"Velikijs","sequence":"additional","affiliation":[{"name":"Department of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peteris","family":"Trapencieris","sequence":"additional","affiliation":[{"name":"Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7393-9524","authenticated-orcid":false,"given":"Ilze","family":"Strumfa","sequence":"additional","affiliation":[{"name":"Department of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1002\/anie.199405991","article-title":"Chiral Aziridines\u2014Their Synthesis and Use in Stereoselective Transformations","volume":"33","author":"Tanner","year":"1994","journal-title":"Angew. 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