{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:01:48Z","timestamp":1785772908153,"version":"3.56.0"},"reference-count":125,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T00:00:00Z","timestamp":1634169600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Endometriosis is a chronic, estrogen-dependent, inflammatory condition that is defined as the presence of endometrial glands and stroma outside the uterine cavity. Despite the progress in research into the mechanisms leading to the development of endometriosis, its cause has not yet been established. It seems to be possible that the formation of oxidative stress may be one of the main causes of the development of endometriosis. There is much research that studies the potential role of trace elements in the appearance of endometrial-like lesions. Most studies focus on assessing the content of selected trace elements in the blood, urine, or peritoneal fluid in women with endometriosis. Meanwhile, little is known about the content of these elements in endometrial-like implants, which may be helpful in developing the theory of endometriosis. Investigations that are more comprehensive are needed to confirm a hypothesis that some trace elements play a role in the pathomechanism of endometriosis.<\/jats:p>","DOI":"10.3390\/ijms222011098","type":"journal-article","created":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T22:42:18Z","timestamp":1634251338000},"page":"11098","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Brief Review of Endometriosis and the Role of Trace Elements"],"prefix":"10.3390","volume":"22","author":[{"given":"Ida","family":"Osuchowska-Grochowska","sequence":"first","affiliation":[{"name":"Department of Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"Blicharska","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Medical University of Lublin, Chod\u017aki 4a, 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Gogacz","sequence":"additional","affiliation":[{"name":"2nd Department of Gynecology, Lublin Medical University, 20-954 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Nogalska","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabela","family":"Winkler","sequence":"additional","affiliation":[{"name":"2nd Department of Gynecology, St John\u2019s Center Oncology, 20-090 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6351-4047","authenticated-orcid":false,"given":"Agnieszka","family":"Szopa","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany, Jagielonian University, Collegium Medicum, 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halina","family":"Ekiert","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany, Jagielonian University, Collegium Medicum, 30-688 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Tymczyna-Borowicz","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry with Endodontics, Medical University of Lublin, 20-439 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5622-7330","authenticated-orcid":false,"given":"Mansur","family":"Rahnama-Hezavah","sequence":"additional","affiliation":[{"name":"Department of Dental Surgery Medical University of Lublin, 20-081 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2938-885X","authenticated-orcid":false,"given":"Cezary","family":"Grochowski","sequence":"additional","affiliation":[{"name":"Laboratory of Virtual Man, Medical University of Lublin, 20-439 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,14]]},"reference":[{"key":"ref_1","first-page":"10","article-title":"How old is endometriosis? 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